{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T01:46:42Z","timestamp":1774921602542,"version":"3.50.1"},"reference-count":28,"publisher":"BMJ","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorax"],"published-print":{"date-parts":[[1990,8,1]]},"DOI":"10.1136\/thx.45.8.591","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T03:22:59Z","timestamp":1229138579000},"page":"591-596","source":"Crossref","is-referenced-by-count":41,"title":["Bronchoalveolar lavage in patients with mild and severe rheumatoid lung disease."],"prefix":"10.1136","volume":"45","author":[{"given":"D M","family":"Gilligan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C M","family":"O'Connor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Ward","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D","family":"Moloney","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B","family":"Bresnihan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M X","family":"FitzGerald","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"471","article-title":"State of the art: Pulmonary involvement in the collagen vascular diseases","volume":"119","author":"Hunninghake, G.W.; Fauci, A.S.","year":"1979","unstructured":"Hunninghake GW, Fauci AS. State of the art: Pulmonary involvement in the collagen vascular diseases. Am Rev Respir Dis 1979;119:471-503.","journal-title":"Am Rev Respir Dis"},{"key":"ref_2","first-page":"237","article-title":"Chronic interstitial lung disease","volume-title":"Current pulmonology","author":"Keogh, B.A.; Crystal, R.G.","year":"1981","unstructured":"Keogh BA, Crystal RG. Chronic interstitial lung disease. In: Simmons DH, ed. Current pulmonology. Chichester: Wiley, 1981:237-340."},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1378\/chest.63.1.27","article-title":"Pulmonary dysfunction in rheumatoid disease","volume":"63","author":"Frank, T.; Weg, J.G.; Harkleroad, L.E.; Fitch, R.F.","year":"1973","unstructured":"Frank T, Weg JG, Harkleroad LE, Fitch RF. Pulmonary dysfunction in rheumatoid disease. Chest 1973;63:27-33.","journal-title":"Chest"},{"key":"ref_4","first-page":"243","article-title":"Interstitial rheumatoid lung disease","volume":"63","author":"Popper, M.S.; Bogdenoff, M.L.; Hughes, R.L.","year":"1972","unstructured":"Popper MS, Bogdenoff ML, Hughes RL. Interstitial rheumatoid lung disease. Chest 1972;63:243-9.","journal-title":"Chest"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"368","DOI":"10.3109\/03009748609098205","article-title":"Diffuse interstitial lung disease in Rheumatoid Arthritis","volume":"15","author":"Hakala, M.; Ruuska, P.; Hameenkorpi, R.; Tiilikainen, A.; Ilonen, J.; Makitalo, R.","year":"1986","unstructured":"Hakala M, Ruuska P, Hameenkorpi R, Tiilikainen A, Ilonen J, Makitalo R. Diffuse interstitial lung disease in Rheumatoid Arthritis. Scand J Rheumatol 1986;15: 368-76.","journal-title":"Scand J Rheumatol"},{"key":"ref_6","first-page":"395","article-title":"A systematic controlled study of pulmonary abnormalities in Rheumatoid arthritis","volume":"10","author":"Hyland, R.H.; Gordon, R.A.; Broder, I.","year":"1983","unstructured":"Hyland RH, Gordon RA, Broder I. A systematic controlled study of pulmonary abnormalities in Rheumatoid arthritis. J Rheumatol 1983;10:395-406.","journal-title":"J Rheumatol"},{"key":"ref_7","first-page":"1","article-title":"Cryptogenic fibrosing alveolitis: relationships ofpulmonary physiology and bronchoalveolar lavage to response to treatment and prognosis","volume":"124","author":"Rudd, R.M.; Haslam, P.L.; Turner-Warwick, M.","year":"1981","unstructured":"Rudd RM, Haslam PL, Turner-Warwick M. Cryptogenic fibrosing alveolitis: relationships ofpulmonary physiology and bronchoalveolar lavage to response to treatment and prognosis. Am Rev Respir Dis 1981;124:1-8.","journal-title":"Am Rev Respir Dis"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1378\/chest.92.1.51","article-title":"Prognostic role of eosinophils in pulmonary fibrosis","volume":"92","author":"Peterson, M.W.; Monick, M.; Hunninghake, G.W.","year":"1987","unstructured":"Peterson MW, Monick M, Hunninghake GW. Prognostic role of eosinophils in pulmonary fibrosis. Chest 1987;92: 51-6.","journal-title":"Chest"},{"key":"ref_9","first-page":"450","article-title":"Bronchoalveolar lavage fluid evaluation in rheumatoid arthritis","volume":"133","author":"Garcia, J.G.N.; Parhami, N.; Killam, D.; Garcia, P.L.; Keogh, B.A.","year":"1986","unstructured":"Garcia JGN, Parhami N, Killam D, Garcia PL, Keogh BA. Bronchoalveolar lavage fluid evaluation in rheumatoid arthritis. Am Rev Respir Dis 1986;133:450-4.","journal-title":"Am Rev Respir Dis"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"628","DOI":"10.1152\/jappl.1987.62.2.628","article-title":"Neutrophil collagenase in rheumatoid interstitial lung disease","volume":"62","author":"Weiland, J.E.; Garcia, J.G.N.; Davis, W.B.; Gadek, J.E.","year":"1987","unstructured":"Weiland JE, Garcia JGN, Davis WB, Gadek JE. Neutrophil collagenase in rheumatoid interstitial lung disease. J Appl Physiol 1987;62:628-33.","journal-title":"J Appl Physiol"},{"key":"ref_11","first-page":"547","article-title":"Bronchoalveolar lavage-a sensitive tool for early diagnosis of pulmonary involvement in rheumatoid arthritis","volume":"13","author":"Tishler, M.; Grief, J.; Fireman, E.; Yanow, M.; Topilsky, M.","year":"1986","unstructured":"Tishler M, Grief J, Fireman E, Yanow M, Topilsky M. Bronchoalveolar lavage-a sensitive tool for early diagnosis of pulmonary involvement in rheumatoid arthritis. J Rheumatol 1986;13:547-50.","journal-title":"J Rheumatol"},{"key":"ref_12","first-page":"574","article-title":"Subclinical pulmonary involvement in collagen vascular diseases assessed by bronchoalveolar lavage. Relationship between alveolitis and subsequent changes in lung function","volume":"133","author":"Wallaert, B.; Hatron, P.Y.; Grosbois, J.M.; Tonnel, A.B.; Devulder, B.; Voisin, C.","year":"1986","unstructured":"Wallaert B, Hatron PY, Grosbois JM, Tonnel AB, Devulder B, Voisin C. Subclinical pulmonary involvement in collagen vascular diseases assessed by bronchoalveolar lavage. Relationship between alveolitis and subsequent changes in lung function. Am Rev Respir Dis 1986;133: 574-80.","journal-title":"Am Rev Respir Dis"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1056\/NEJM197910043011401","article-title":"Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis","volume":"301","author":"Gadek, J.E.; Kelman, J.A.; Fells, G.","year":"1979","unstructured":"Gadek JE, Kelman JA, Fells G, et al. Collagenase in the lower respiratory tract of patients with idiopathic pulmonary fibrosis. N Engl J Med 1979;301:737-42.","journal-title":"N Engl J Med"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1136\/thx.43.5.393","article-title":"Collagenase and fibronectin in bronchoalveolar lavage fluid in patients with sarcoidosis","volume":"43","author":"O'Connor, C.; Odlum, C.; van Breda, A.; Power, C.; FitzGerald, M.X.","year":"1988","unstructured":"O'Connor C, Odlum C, van Breda A, Power C, FitzGerald MX. Collagenase and fibronectin in bronchoalveolar lavage fluid in patients with sarcoidosis. Thorax 1988;43: 393-400.","journal-title":"Thorax"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1164\/ajrccm\/137.3.572","article-title":"Increased procollagen III amino terminal peptide-related antigens and fibroblast growth signals in the lungs of patients with idiopathic pulmonary fibrosis","volume":"137","author":"Cantin, A.M.; Boileau, R.; Begin, R.","year":"1988","unstructured":"Cantin AM, Boileau R, Begin R. Increased procollagen III amino terminal peptide-related antigens and fibroblast growth signals in the lungs of patients with idiopathic pulmonary fibrosis. Am Rev Respir Dis 1988;137:572-8.","journal-title":"Am Rev Respir Dis"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"741","DOI":"10.1001\/jama.1964.03070210047009","article-title":"Primer on the rheumatic diseases","volume":"190","author":"Decker, J.L.","year":"1964","unstructured":"Decker JL. Primer on the rheumatic diseases. JAMA 1964; 190:741-51.","journal-title":"JAMA"},{"key":"ref_17","article-title":"Guidelines for the use of ILO international classification of radiographs ofpneumoconiosis","author":"Office, International Labour","year":"1983","unstructured":"International Labour Office. Guidelines for the use of ILO international classification of radiographs ofpneumoconiosis. Geneva: ILO, 1983."},{"key":"ref_18","first-page":"329","article-title":"Lung function: assessment and application in medicine","author":"Cotes, J.E.","year":"1979","unstructured":"Cotes JE. Lung function: assessment and application in medicine. Oxford: Blackwell, 1979:329-87."},{"key":"ref_19","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1378\/chest.96.2.339","article-title":"Type III procollagen peptide in bronchoalveolar lavage fluid: poor indicator of course and prognosis in sarcoidosis","volume":"96","author":"O'Connor, C.; Ward, K.; van Breda, A.; McIlgorm, A.; FitzGerald, M.X.","year":"1989","unstructured":"O'Connor C, Ward K, van Breda A, McIlgorm A, FitzGerald MX. Type III procollagen peptide in bronchoalveolar lavage fluid: poor indicator of course and prognosis in sarcoidosis. Chest 1989;96:339-44.","journal-title":"Chest"},{"key":"ref_20","first-page":"250","article-title":"Bronchoalveolar lavage","volume":"135","author":"Reynolds, H.Y.","year":"1987","unstructured":"Reynolds HY. Bronchoalveolar lavage. Am Rev Respir Dis 1987;135:250-63.","journal-title":"Am Rev Respir Dis"},{"key":"ref_21","article-title":"Statistical methods","author":"Snedecor, G.W.; Cochran, W.G.","year":"1967","unstructured":"Snedecor GW, Cochran WG. Statistical methods. 6th ed. Iowa State University Press, 1967.","edition":"6th ed"},{"key":"ref_22","first-page":"897","article-title":"Granulocyte collagenase: selective digestion of type I relative to","volume-title":"type III collagen. Proc Natl Acad Sci USA","volume":"74","author":"Horwitz, A.L.; Hance, A.J.; Crystal, R.G.","year":"1977","unstructured":"Horwitz AL, Hance AJ, Crystal RG. Granulocyte collagenase: selective digestion of type I relative to type III collagen. Proc Natl Acad Sci USA 1977;74:897-901."},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/0002-9343(81)90577-5","article-title":"Interstitial lung disease: current concepts of pathogenesis, staging and therapy","volume":"70","author":"Crystal, R.G.; Gadek, J.E.; Ferrens, V.J.; Fulmer, J.D.; Line, B.R.; Hunninghake, G.W.","year":"1981","unstructured":"Crystal RG, Gadek JE, Ferrens VJ, Fulmer JD, Line BR, Hunninghake GW. Interstitial lung disease: current concepts of pathogenesis, staging and therapy. Am J Med 1981;70:542-68.","journal-title":"Am J Med"},{"key":"ref_24","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1164\/ajrccm\/136.4.811","article-title":"Lower respiratory tract abnormalities in rheumatoid interstitial lung disease. Potential role of neutrophils in lung injury","volume":"136","author":"Garcia, J.G.N.; James, H.L.; Zinkgraf, S.; Perlman, M.B.; Keogh, B.A.","year":"1987","unstructured":"Garcia JGN, James HL, Zinkgraf S, Perlman MB, Keogh BA. Lower respiratory tract abnormalities in rheumatoid interstitial lung disease. Potential role of neutrophils in lung injury. Am Rev Respir Dis 1987;136:811-7.","journal-title":"Am Rev Respir Dis"},{"key":"ref_25","first-page":"755","article-title":"Lavage type III procollagen N-terminal peptides in human pulmonary fibrosis and sarcoidosis","volume":"48","author":"Low, R.B.; Cutroneo, K.R.; Davis, G.S.; Granala, M.S.","year":"1983","unstructured":"Low RB, Cutroneo KR, Davis GS, Granala MS. Lavage type III procollagen N-terminal peptides in human pulmonary fibrosis and sarcoidosis. Lab Invest 1983;48: 755-9.","journal-title":"Lab Invest"},{"key":"ref_26","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1136\/thx.38.2.93","article-title":"Cryptogenic fibrosing alveolitis: prediction of fibrogenic activity from immunohistochemical studies of collagen types in lung biopsy specimens","volume":"38","author":"Bateman, E.D.; Turner-Warwick, M.; Haslam, P.; AdelmanGrill, B.C.","year":"1983","unstructured":"Bateman ED, Turner-Warwick M, Haslam P, AdelmanGrill BC. Cryptogenic fibrosing alveolitis: prediction of fibrogenic activity from immunohistochemical studies of collagen types in lung biopsy specimens. Thorax 1983;38: 93-101.","journal-title":"Thorax"},{"key":"ref_27","first-page":"26","article-title":"The value of serial bronchoalveolar lavage in assessing the clinical progress of patients with cryptogenic fibrosing alveolitis","volume":"135","author":"Turner-Warwick, M.; Haslam, P.L.","year":"1987","unstructured":"Turner-Warwick M, Haslam PL. The value of serial bronchoalveolar lavage in assessing the clinical progress of patients with cryptogenic fibrosing alveolitis. Am Rev Respir Dis 1987;135:26-34.","journal-title":"Am Rev Respir Dis"},{"key":"ref_28","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1136\/thx.35.1.9","article-title":"Bronchoalveolar lavage in pulmonary fibrosis: comparison of cells obtained with lung biopsy and clinical features","volume":"35","author":"Haslam, P.L.; Turton, C.W.G.; Heard, B.","year":"1980","unstructured":"Haslam PL, Turton CWG, Heard B, et al. Bronchoalveolar lavage in pulmonary fibrosis: comparison of cells obtained with lung biopsy and clinical features. Thorax 1980;35: 9-18.","journal-title":"Thorax"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thx.45.8.591","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T09:10:52Z","timestamp":1601111452000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thx.45.8.591"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,8,1]]},"references-count":28,"journal-issue":{"issue":"8","published-print":{"date-parts":[[1990,8,1]]}},"URL":"https:\/\/doi.org\/10.1136\/thx.45.8.591","relation":{},"ISSN":["0040-6376"],"issn-type":[{"value":"0040-6376","type":"print"}],"subject":[],"published":{"date-parts":[[1990,8,1]]}}}