{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,3]],"date-time":"2026-10-03T18:06:33Z","timestamp":1791050793075,"version":"4.1.0"},"reference-count":19,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorax"],"published-print":{"date-parts":[[1995,4,1]]},"DOI":"10.1136\/thx.50.4.387","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T03:22:59Z","timestamp":1229138579000},"page":"387-391","source":"Crossref","is-referenced-by-count":33,"title":["Attenuation of ischaemia reperfusion injury by human thioredoxin."],"prefix":"10.1136","volume":"50","author":[{"given":"T","family":"Fukuse","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Hirata","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Yokomise","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K","family":"Inui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A","family":"Mitsui","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T","family":"Hirakawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S","family":"Hitomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J","family":"Yodoi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H","family":"Wada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"262","article-title":"Inhibition of surgically induced ischemia\/reperfusion injury by oxygen free radical scavengers","volume":"83","author":"Stewart, JR, Blackwell; WH, Crute; SL, Loughlin; V, Greenfield; U, Hess; M.L.","year":"1983","unstructured":"Stewart JR, Blackwell WH, Crute SL, Loughlin V, Greenfield U, Hess ML. Inhibition of surgically induced ischemia\/reperfusion injury by oxygen free radical scavengers. J Thorac Cardiovasc Surg 1983;83:262-72.","journal-title":"J Thorac Cardiovasc Surg"},{"key":"ref_2","first-page":"22","article-title":"Super oxide radicals","volume-title":"feline intestinal ischemia. Gastroenterology 1981; 81","author":"Granger, D.N.; Rutili, G.; McCord, J.M.","unstructured":"Granger DN, Rutili G, McCord JM. Super oxide radicals in feline intestinal ischemia. Gastroenterology 1981;81:22-9."},{"key":"ref_3","first-page":"428","article-title":"Role of oxygen free radicals in shock, ischemia, and organ preservation","volume":"94","author":"Parks, D.A.; Bulkley, G.B.; Granger, N.","year":"1983","unstructured":"Parks DA, Bulkley GB, Granger N. Role of oxygen free radicals in shock, ischemia, and organ preservation. Surgery 1983;94:428-32.","journal-title":"Surgery"},{"key":"ref_4","first-page":"30","article-title":"Pulmonary reimplantation response","volume":"177","author":"Siegelman, S.S.; Sinha, S.B.P.; Veith, F.J.","year":"1973","unstructured":"Siegelman SS, Sinha SBP, Veith FJ. Pulmonary reimplantation response. Ann Surg 1973;177:30-6."},{"key":"ref_5","first-page":"17","article-title":"Adult T leukemia cells produce a lymphokine that augments interleukin 2 receptor expression","volume":"2","author":"Teshigawara, K.; Maeda, M.; Nishino, K.; Nikaido, T.; Uchiyama, T.; Tsudo, M.","year":"1985","unstructured":"Teshigawara K, Maeda M, Nishino K, Nikaido T, Uchiyama T, Tsudo M, et al. Adult T leukemia cells produce a lymphokine that augments interleukin 2 receptor expression. Mol Cell Biol 1985;2:17-26. _J","journal-title":"Mol Cell Biol"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1146\/annurev.bi.54.070185.001321","volume":"54","author":"Thioredoxin, Holmgren A.","year":"1985","unstructured":"Holmgren A. Thioredoxin. Ann Rev Biochem 1985;54:237-71.","journal-title":"Ann Rev Biochem"},{"key":"ref_7","first-page":"127989","article-title":"Role of ATL-derived factor (ADF) in the normal and abnormal cellular activation: involvement of dithiol related reduction","volume":"27","author":"Tagaya, Y.; Wakasugi, H.; Masutani, H.; Nakamura, H.; Iwata, S.; Mitsui, A.","year":"1990","unstructured":"Tagaya Y, Wakasugi H, Masutani H, Nakamura H, Iwata S, Mitsui A, et al. Role of ATL-derived factor (ADF) in the normal and abnormal cellular activation: involvement of dithiol related reduction. Mol Immunol 1990;27:127989.","journal-title":"Mol Immunol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"4984","DOI":"10.1016\/S0021-9258(18)68884-2","article-title":"The effect ofH202 upon thioredoxinenriched lens epithelial cells","volume":"263","author":"Spector, A.; Yan, G.Z.; Huang, R.R.C.; McDermott, M.J.; Gascoyne, P.R.C.; Pigiet, V.","year":"1988","unstructured":"Spector A, Yan GZ, Huang RRC, McDermott MJ, Gascoyne PRC, Pigiet V. The effect ofH202 upon thioredoxinenriched lens epithelial cells. JBiol Chem 1988;263:4984-90.","journal-title":"JBiol Chem"},{"key":"ref_9","first-page":"3837","article-title":"Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells","volume":"147","author":"Matsuda, M.; Masutani, H.; Nakamura, H.; Miyajima, S.; Yamauchi, A.; Yonehara, S.","year":"1991","unstructured":"Matsuda M, Masutani H, Nakamura H, Miyajima S, Yamauchi A, Yonehara S, et al. Protective activity of adult T cell leukemia-derived factor (ADF) against tumor necrosis factor-dependent cytotoxicity on U937 cells. Immunol 1991;147:3837-44.","journal-title":"Immunol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1016\/S0006-291X(05)81536-0","article-title":"Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemiaderived factor(ADF)\/human thioredoxin","volume":"186","author":"Mitsui, A.; Hirakawa, T.; Yodoi, J.","year":"1992","unstructured":"Mitsui A, Hirakawa T, Yodoi J. Reactive oxygen-reducing and protein-refolding activities of adult T cell leukemiaderived factor(ADF)\/human thioredoxin. Biochem Biophys Res Commun 1992;186:1220-6.","journal-title":"Biochem Biophys Res Commun"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"304","DOI":"10.1055\/s-2007-1013877","article-title":"Preparation of in-vivo rat lung model for ischemiareperfusion injury","volume":"41","author":"Ohno, N.; Yokomise, H.; Fukuse, T.; Hirata, T.; Hitomi, S.; Wada, H.","year":"1993","unstructured":"Ohno N, Yokomise H, Fukuse T, Hirata T, Hitomi S, Wada H. Preparation of in-vivo rat lung model for ischemiareperfusion injury. Thorac Cardiovasc Surg 1993;41:304-7.","journal-title":"Thorac Cardiovasc Surg"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1159\/000196315","article-title":"Effect of recombinant human adult T cell leukemia-derived factor on rat lung reperfusion injury","volume":"61","author":"Yokomise, H.; Fukuse, T.; Hirata, T.; Ohkubo, K.; Go, T.; Muro, K.","year":"1994","unstructured":"Yokomise H, Fukuse T, Hirata T, Ohkubo K, Go T, Muro K, et al. Effect of recombinant human adult T cell leukemia-derived factor on rat lung reperfusion injury. Respiration 1994;61:99-104.","journal-title":"Respiration"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa, H.; Ohishi, N.; Yagi, K.","year":"1979","unstructured":"Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-8.","journal-title":"Anal Biochem"},{"key":"ref_14","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/S0076-6879(84)05015-1","article-title":"Assays of glutathione peroxidase","volume":"105","author":"Flohe, L.; Gunzler, W.A.","year":"1984","unstructured":"Flohe L, Gunzler WA. Assays of glutathione peroxidase. Methods Enzymol 1984;105:114-21.","journal-title":"Methods Enzymol"},{"key":"ref_15","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0076-6879(84)05013-8","article-title":"Superoxide dismutase assays","volume":"105","author":"Flohe, L.; Otting, F.","year":"1984","unstructured":"Flohe L, Otting F. Superoxide dismutase assays. Methods Enzymol 1984;105:93-104.","journal-title":"Methods Enzymol"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1152\/jappl.1990.68.1.374","article-title":"Neutrophils are not necessary for induction of ischemia-reperfusion lung injury","volume":"68","author":"Deeb, G.M.; Grum, C.M.; Lynch, M.J.; Guynn, T.P.; Gallagher, K.P.; Ljungman, A.G.","year":"1990","unstructured":"Deeb GM, Grum CM, Lynch MJ, Guynn TP, Gallagher KP, Ljungman AG, et al. Neutrophils are not necessary for induction of ischemia-reperfusion lung injury. Appl Physiol 1990;68:374-81.","journal-title":"Appl Physiol"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1002\/j.1460-2075.1989.tb03436.x","article-title":"ATL-derived factor (ADF), an IL-2 receptor\/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction","volume":"8","author":"Tagaya, Y.; Okada, M.; Sugie, K.; Kasahara, T.; Kondo, N.; Hamuro, J.","year":"1989","unstructured":"Tagaya Y, Okada M, Sugie K, Kasahara T, Kondo N, Hamuro J, et al. ATL-derived factor (ADF), an IL-2 receptor\/Tac inducer homologous to thioredoxin; possible involvement of dithiol-reduction in the IL-2 receptor induction. EMBOJ 1989;8:757-64.","journal-title":"EMBOJ"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/0003-4975(90)90735-O","article-title":"Oxygen free radical scavengers decrease reperfusion injury in the lung transplantation","volume":"50","author":"Detterbeck, F.C.; Keagy, B.A.; Paull, D.E.; Wilcox, B.R.","year":"1990","unstructured":"Detterbeck FC, Keagy BA, Paull DE, Wilcox BR. Oxygen free radical scavengers decrease reperfusion injury in the lung transplantation. Ann Thorac Surg 1990;50:204-10.","journal-title":"Ann Thorac Surg"},{"key":"ref_19","first-page":"9","volume":"548","author":"Oxygen, Weiss S.J.; ischemia; inflammation","year":"1986","unstructured":"Weiss SJ. Oxygen, ischemia and inflammation. Acta Physiol Scand 1986;548(Suppl):9-37.","journal-title":"Acta Physiol Scand"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thx.50.4.387","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,9,27]],"date-time":"2021-09-27T19:16:47Z","timestamp":1632770207000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thx.50.4.387"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,4,1]]},"references-count":19,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1995,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/thx.50.4.387","relation":{},"ISSN":["0040-6376"],"issn-type":[{"value":"0040-6376","type":"print"}],"subject":[],"published":{"date-parts":[[1995,4,1]]}}}