{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T04:57:11Z","timestamp":1773291431773,"version":"3.50.1"},"reference-count":23,"publisher":"BMJ","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Thorax"],"published-print":{"date-parts":[[1996,4,1]]},"DOI":"10.1136\/thx.51.4.389","type":"journal-article","created":{"date-parts":[[2008,12,13]],"date-time":"2008-12-13T03:22:59Z","timestamp":1229138579000},"page":"389-396","source":"Crossref","is-referenced-by-count":17,"title":["Inhibition of the alveolar macrophage oxidative burst by a diffusible component from the surface of the spores of the fungus Aspergillus fumigatus."],"prefix":"10.1136","volume":"51","author":[{"given":"J","family":"Slight","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W J","family":"Nicholson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C G","family":"Mitchell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N","family":"Pouilly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P H","family":"Beswick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A","family":"Seaton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K","family":"Donaldson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","reference":[{"key":"ref_1","first-page":"893","article-title":"Aspergillus, asthma and amoebae","year":"1989","unstructured":"Seaton A, Robertson MD. Aspergillus, asthma and amoebae. Lancet 1989;893-894.","journal-title":"Lancet"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/0954-6111(94)90035-3","article-title":"A new look at the natural history of aspergillus hypersensitivity in asthmatics","volume":"88","author":"Bateman, E.D.","year":"1994","unstructured":"Bateman ED. A new look at the natural history of aspergillus hypersensitivity in asthmatics. Respir Med 1994;88:325-7.","journal-title":"Respir Med"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1111\/j.1365-2222.1976.tb01899.x","article-title":"Sources and incidence of airborne Aspergillusfumigatus","volume":"6","author":"Mullins, J.; Harvey, R.; Seaton, A.","year":"1976","unstructured":"Mullins J, Harvey R, Seaton A. Sources and incidence of airborne Aspergillusfumigatus. Clin Allergy 1976;6:209-17.","journal-title":"Clin Allergy"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"752","DOI":"10.1093\/infdis\/150.5.752","article-title":"In vivo bronchoalveolar macrophage defence against Rhizopus oryzae and Aspergillus fumigatus. J'","volume":"150","author":"Waldorf, A.R.; Lentz, S.M.; Diamond, R.D.","year":"1984","unstructured":"Waldorf AR, Lentz SM, Diamond RD. In vivo bronchoalveolar macrophage defence against Rhizopus oryzae and Aspergillus fumigatus. J' Infect Dis 1984;150:752-60.","journal-title":"Infect Dis"},{"key":"ref_5","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1136\/thx.42.6.466","article-title":"Resistance of spores of Aspergillus fumigatus to ingestion by phagocytic cells","volume":"42","author":"Robertson, M.D.; Seaton, A.; Milne, L.J.R.; Raeburn, J.A.","year":"1987","unstructured":"Robertson MD, Seaton A, Milne LJR, Raeburn JA. Resistance of spores of Aspergillus fumigatus to ingestion by phagocytic cells. Thorax 1987;42:466-72.","journal-title":"Thorax"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1136\/thx.42.1.19","article-title":"Suppression of host defences by Aspergillus fumigatus","volume":"42","author":"Robertson, M.D.; Seaton, A.; Milne, L.J.R.; Raeburn, J.A.","year":"1987","unstructured":"Robertson MD, Seaton A, Milne LJR, Raeburn JA. Suppression of host defences by Aspergillus fumigatus. Thorax 1987;42:19-25.","journal-title":"Thorax"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1080\/02681218780000471","article-title":"Inhibition of phagocyte migration and spreading by spore diffusates of Aspergillus funzigatus","volume":"25","author":"Robertson, M.D.; Seaton, A.; Raebum, J.A.; Milne, L.J.R.","year":"1987","unstructured":"Robertson MD, Seaton A, Raebum JA, Milne LJR. Inhibition of phagocyte migration and spreading by spore diffusates of Aspergillus funzigatus. _7 Med Vet Mycol 1987; 25:389-96.","journal-title":"_7 Med Vet Mycol"},{"key":"ref_8","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/S0091-6749(05)80176-9","article-title":"Allergens as proteases: Aspergillus fumigattis protease directly induces human epithelial cell detachment","volume":"86","author":"Robinson, B.W.S.; Venaille, T.J.; Mende, A.H.W.; McAleer, R.","year":"1990","unstructured":"Robinson BWS, Venaille TJ, Mende AHW, McAleer R. Allergens as proteases: Aspergillus fumigattis protease directly induces human epithelial cell detachment. 7 Allergy Clitz Imnunol 1990;86:726-31.","journal-title":"7 Allergy Clitz Imnunol"},{"key":"ref_9","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1099\/00222615-33-4-243","article-title":"Purification and characterisation of an extracellular serine protease from Aspergillus funzigatus and its detection in tissue","volume":"33","author":"Reichard, V.Buthner S.Eiffert H.Ruchel R.","year":"1990","unstructured":"Reichard, V. Buthner S. Eiffert H. Ruchel R. Purification and characterisation of an extracellular serine protease from Aspergillus funzigatus and its detection in tissue. Med Microbiol 1990;33:243-51.","journal-title":"Med Microbiol"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1084\/jem.148.1.115","article-title":"Increased superoxide by immunologically activated and chemically elicited macrophages","volume":"148","author":"Johnson, R.B.; Godzik, C.A.; Cohn, Z.A.","year":"1978","unstructured":"Johnson RB, Godzik CA, Cohn ZA. Increased superoxide by immunologically activated and chemically elicited macrophages. 7 Exp Med 1978;148:115-27.","journal-title":"7 Exp Med"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"350","DOI":"10.1021\/ac60111a017","article-title":"Colorimetric method for determination of sugars and related substances","volume":"28","author":"Dubois, M.; Gillies, K.A.; Hamilton, J.K.; Rebers, P.A.; Smith, F.","year":"1956","unstructured":"Dubois M, Gillies KA, Hamilton JK, Rebers PA, Smith F. Colorimetric method for determination of sugars and related substances. Anal Chern 1956;28:350-6.","journal-title":"Anal Chern"},{"key":"ref_12","doi-asserted-by":"crossref","first-page":"229","DOI":"10.3109\/08820138409025464","article-title":"An improved macrophage spreading assay - a simple and effective measure of activation","volume":"13","author":"Donaldson, K.; Bolton, R.E.; Brown, D.M.; Douglas, A.","year":"1984","unstructured":"Donaldson K, Bolton RE, Brown DM, Douglas A. An improved macrophage spreading assay - a simple and effective measure of activation. Inmnmunol Commun 1984; 13:229-44.","journal-title":"Inmnmunol Commun"},{"key":"ref_13","doi-asserted-by":"crossref","first-page":"676","DOI":"10.1136\/thx.49.7.676","article-title":"Characterisation of an oxidative response inhibitor produced by Streptococciis pneunioniae","volume":"49","author":"Perry, F.E.; Elson, C.J.; Mitchell, T.J.; Andrew, P.W.; Catterall, JR","year":"1994","unstructured":"Perry FE, Elson CJ, Mitchell TJ, Andrew PW, Catterall JR. Characterisation of an oxidative response inhibitor produced by Streptococciis pneunioniae. Thorax 1994;49: 676-83.","journal-title":"Thorax"},{"key":"ref_14","first-page":"3354","article-title":"Selective expression of a major allergen and cytotoxin, Asp f I in Aspergillus fumigatus: implications for the immunopathogenesis of aspergillus-related diseases","volume":"10","year":"1992","unstructured":"Arruda KL, Mann BJ, Chapman MD. Selective expression of a major allergen and cytotoxin, Asp f I in Aspergillus fumigatus: implications for the immunopathogenesis of aspergillus-related diseases. _7 Inmmunol 1992;10:3354-9."},{"key":"ref_15","first-page":"1913","article-title":"Interactions between conidia of Aspergillus fumigatus and human complement component C3","volume":"60","author":"Sturtevant, J.E.; Latge, J.-P.","year":"1992","unstructured":"Sturtevant JE, Latge J-P. Interactions between conidia of Aspergillus fumigatus and human complement component C3. Infect Inimnun 1992;60:1913-8.","journal-title":"Infect Inimnun"},{"key":"ref_16","doi-asserted-by":"crossref","first-page":"735","DOI":"10.1016\/S0040-4039(00)84087-3","article-title":"The isolation and identification of a new metabolite from Aspergillus fiunigatus related to gliotoxin","volume":"27","author":"Waring, P.; Eichner, R.D.; Tiwari-Palni, U.; Mullbacher, A.","year":"1986","unstructured":"Waring P, Eichner RD, Tiwari-Palni U, Mullbacher A. The isolation and identification of a new metabolite from Aspergillus fiunigatus related to gliotoxin. Tetrahedroni Lett 1986;27:735-8.","journal-title":"Tetrahedroni Lett"},{"key":"ref_17","doi-asserted-by":"crossref","first-page":"3835","DOI":"10.1073\/pnas.81.12.3835","article-title":"Immunosuppression in vitro by a metabolite of a human pathogenic fungus","volume":"81","author":"Miillbacher, A.; Eichner, R.D.","year":"1984","unstructured":"Miillbacher A, Eichner RD. Immunosuppression in vitro by a metabolite of a human pathogenic fungus. PNAS 1984;81:3835-7.","journal-title":"PNAS"},{"key":"ref_18","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1099\/00221287-131-5-1251","article-title":"Identification of an agent in cultures of Aspergillus fumigatus displaying antiphagocytic and immunomodulating activity in vitro","volume":"13","author":"Mullbacher, A.; Waring, P.; Eichner, R.D.","year":"1985","unstructured":"Mullbacher A, Waring P, Eichner RD. Identification of an agent in cultures of Aspergillus fumigatus displaying antiphagocytic and immunomodulating activity in vitro. Gen Microbiol 1985;13:1251-8.","journal-title":"Gen Microbiol"},{"key":"ref_19","first-page":"789","article-title":"The effect of gliotoxin upon macrophage function","volume":"8","author":"Eichner, R.D.; AlSalami, M.; Wood, P.R.; Mullbacher, A.","year":"1986","unstructured":"Eichner RD, AlSalami M, Wood PR, Mullbacher A. The effect of gliotoxin upon macrophage function. Ilot 7 Immnzunopharmiacol 1986;8:789-97."},{"key":"ref_20","first-page":"547","article-title":"Monoclonal antibodies bind identically to both spores and hyphae ofAspergillisfuwnigatus. Clin Exp Allergy","volume":"22","author":"Reijula, K.E.","year":"1992","unstructured":"Reijula KE. Monoclonal antibodies bind identically to both spores and hyphae ofAspergillisfuwnigatus. Clin Exp Allergy 1992;22:547-53."},{"key":"ref_21","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1016\/0891-5849(90)90147-B","article-title":"Inhibitors of the leukocyte superoxide generating system","volume":"8","author":"Cross, A.","year":"1990","unstructured":"Cross A. Inhibitors of the leukocyte superoxide generating system. Free Radical Biol Med 1990;8:71-93.","journal-title":"Free Radical Biol Med"},{"key":"ref_22","first-page":"131","article-title":"Assembly and regulation of NADPH oxidase and NO synthase","volume":"6","author":"Bastian, N.R.; Hibbs, J.B.","year":"1994","unstructured":"Bastian NR, Hibbs JB. Assembly and regulation of NADPH oxidase and NO synthase. Curr Opin Biol 1994;6: 131-3.","journal-title":"Curr Opin Biol"},{"key":"ref_23","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1126\/science.7878466","article-title":"Control of IKB-alpha proteolysis by site-specific, signal induced phosphorylation","volume":"267","author":"Brown, K.; Gerstberger, S.; Carlson, L.; Franzoso, G.; Siebenlist, U.","year":"1995","unstructured":"Brown K, Gerstberger S, Carlson L, Franzoso G, Siebenlist U. Control of IKB-alpha proteolysis by site-specific, signal induced phosphorylation. Science 1995;267:1485-9.","journal-title":"Science"}],"container-title":["Thorax"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/thx.51.4.389","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,26]],"date-time":"2020-09-26T09:24:28Z","timestamp":1601112268000},"score":1,"resource":{"primary":{"URL":"https:\/\/thorax.bmj.com\/lookup\/doi\/10.1136\/thx.51.4.389"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,4,1]]},"references-count":23,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1996,4,1]]}},"URL":"https:\/\/doi.org\/10.1136\/thx.51.4.389","relation":{},"ISSN":["0040-6376"],"issn-type":[{"value":"0040-6376","type":"print"}],"subject":[],"published":{"date-parts":[[1996,4,1]]}}}