{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T03:42:15Z","timestamp":1771299735990,"version":"3.50.1"},"reference-count":47,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2025,1,18]],"date-time":"2025-01-18T00:00:00Z","timestamp":1737158400000},"content-version":"unspecified","delay-in-days":17,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/100006093","name":"Patient-Centered Outcomes Research Institute","doi-asserted-by":"publisher","award":["IHS-2017C1-6151"],"award-info":[{"award-number":["IHS-2017C1-6151"]}],"id":[{"id":"10.13039\/100006093","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Trauma Surg Acute Care Open"],"accepted":{"date-parts":[[2024,12,21]]},"published-print":{"date-parts":[[2025,1]]},"abstract":"\n Objectives<\/jats:title>\n The goal of the current study was to assess the effectiveness of a peer integrated collaborative care intervention for postinjury outcomes.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n Injury survivors \u226518 years of age were screened for post-traumatic stress disorder (PTSD) symptoms and severe postinjury concerns; screen-positive patients were randomized to the intervention versus enhanced usual care control conditions. The collaborative care intervention included peer support and care management. The intervention also included evidence-based pharmacotherapy and psychotherapeutic elements targeting PTSD. The COVID-19 pandemic interrupted recruitment between March and June 2020; in response to the COVID-19 pandemic, the peer component of the intervention went from in-person to virtual delivery. The primary outcomes were PTSD symptoms assessed with the Diagnostic and Statistical Manual of Mental Disorders fourth edition PTSD checklist, any severe postinjury concerns, and emergency department\/inpatient utilization followed over the 12 months postinjury. Secondary outcomes included patient satisfaction with emotional healthcare.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n A total of 450 patients were randomized to the intervention (n=225) and control (n=225) conditions; 124 patients (28%) were recruited and completed all study assessments prior to the onset of the COVID-19 pandemic, while 326 patients (72%) were recruited after and\/or had one or more study follow-ups occur postpandemic onset. Mixed model regression revealed no statistically significant comparisons for any of the primary outcomes. In exploratory models that examined the impact of COVID-19, significantly improved PTSD symptoms were present at 3 months pre-COVID-19 relative to post-COVID-19. Intervention patients consistently demonstrated higher satisfaction with emotional aspects of healthcare (F(5,1652)=2.87, p=0.01).<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The intervention demonstrated no significant improvements in primary outcomes in the intent-to-treat sample. The peer integrated collaborative care intervention contributed to higher patient satisfaction with the emotional aspects of healthcare.<\/jats:p>\n <\/jats:sec>\n \n Level of evidence<\/jats:title>\n Level II, randomized clinical trial.<\/jats:p>\n <\/jats:sec>\n \n Trial registration number<\/jats:title>\n \n NCT03569878<\/jats:ext-link>.<\/jats:p>\n <\/jats:sec>","DOI":"10.1136\/tsaco-2024-001657","type":"journal-article","created":{"date-parts":[[2025,1,20]],"date-time":"2025-01-20T01:45:20Z","timestamp":1737337520000},"page":"e001657","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Randomized clinical trial of peer integrated collaborative care intervention after physical 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Psychometric review of ptsd checklist (pcl-c, pcl-s. pcl-m, pcl-pr). In: Stamm B , ed. Measurement of stress, trauma, and adaptation. 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SF-36 health survey: manual and interpretation guide. Boston, MA: The Health Institute, New England Medical Center, 1993."},{"key":"2025082410205981000_10.1.e001657.36","unstructured":"The Johns Hopkins Health Services Research and Development Center . Determining injury severity from hospital sischarges: A program to map ICD-9DM diagnoses into AIS, and ISS severity scores; 1989, Baltimore, MD."},{"key":"2025082410205981000_10.1.e001657.37","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.clinpsy.032408.153550"},{"key":"2025082410205981000_10.1.e001657.38","unstructured":"Agency for Healthcare Research & Quality . Psychological and pharmacological treatments for adults with posttraumatic stress disorder (ptsd); 2013, Rockville, MD."},{"key":"2025082410205981000_10.1.e001657.39","article-title":"Multiple session early psychological interventions for the prevention of post-traumatic stress disorder","volume":"2019","author":"Roberts","year":"2009","journal-title":"Cochrane Database Syst Rev"},{"key":"2025082410205981000_10.1.e001657.40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpr.2018.05.001"},{"key":"2025082410205981000_10.1.e001657.41","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1097\/TA.0000000000002371","article-title":"The role of psychological support interventions in trauma patients on mental health outcomes: A systematic review and meta-analysis","volume":"87","author":"Pham","year":"2019","journal-title":"J Trauma Acute Care Surg"},{"key":"2025082410205981000_10.1.e001657.42","doi-asserted-by":"crossref","first-page":"957","DOI":"10.1016\/j.biopsych.2012.06.002","article-title":"Early intervention may prevent the development of posttraumatic stress disorder: a randomized pilot civilian study with modified prolonged exposure","volume":"72","author":"Rothbaum","year":"2012","journal-title":"Biol Psychiatry"},{"key":"2025082410205981000_10.1.e001657.43","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1097\/TA.0000000000003592","article-title":"Does patient preference for online or telephone follow-up impact on response rates and data completeness following injury?","volume":"93","author":"Gabbe","year":"2022","journal-title":"J Trauma Acute Care Surg"},{"key":"2025082410205981000_10.1.e001657.44","doi-asserted-by":"crossref","unstructured":"Palinkas L . 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