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Building on the previous year\u2019s minimum viable product, this conference progressed from conceptualization to design phase, focusing on creating scalable, sustainable solutions for trauma clinical guidance. Participants explored innovative approaches addressing critical challenges in trauma care, including interorganizational collaboration, resource-adaptable guidance, and patient-centered design. The conference highlighted the integration of artificial intelligence (AI) to enhance guidance development and maintain clinical expertise and ethical standards. A key advancement was the refinement of a central repository containing 258 guidance documents in the form of an app with improved accessibility features. Discussions emphasized the importance of implementation science principles, advocating for leadership engagement, maintaining academic recognition for guidance contributions, and continuous outcome tracking. The proposed 12-step guidance development process integrates AI capabilities and preserving clinician expertise. Patient voices and lived experiences were emphasized as essential elements in developing trauma-informed systems, with powerful testimonials from trauma survivors illustrating the critical need for comprehensive support services. Participants agreed that practical guidance must be contextually relevant, properly vetted, and integrate seamlessly with electronic health records. The conference concluded with plans to secure sustainable funding, formalize partnerships, and engage broader communities. 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