{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:38:06Z","timestamp":1773283086348,"version":"3.50.1"},"reference-count":35,"publisher":"Wiley","issue":"8","license":[{"start":{"date-parts":[[2014,8,30]],"date-time":"2014-08-30T00:00:00Z","timestamp":1409356800000},"content-version":"vor","delay-in-days":29,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2014,8]]},"abstract":"<jats:p>\n                    The aim of this study was to assess the prevalence and risk factors for faecal carriage of extended\u2010spectrum \u03b2\u2010lactamase (ESBL) and plasmidic AmpC \u03b2\u2010lactamase (pAmpC)\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    producers in dogs. A three\u2010month cross\u2010sectional study was conducted and 151 rectal swabs were obtained from healthy dogs. ESBL and pAmpC genes were detected by PCR and were sequenced. Logistic regression models were used to investigate risk factors for the carriage of ESBL and pAmpC\u2010producing\n                    <jats:italic>E. coli<\/jats:italic>\n                    . About 15 per cent of the isolates carried ESBL genes (\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX\u2010M\u201032<\/jats:sub>\n                    n=8,\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX\u2010M\u201015<\/jats:sub>\n                    n=5,\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX\u2010M\u20101<\/jats:sub>\n                    n=3,\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CTX\u2010M\u20109\u2010like<\/jats:sub>\n                    n=4) and 20 per cent carried pAmpC genes (\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>CMY\u20102<\/jats:sub>\n                    n=23, bla\n                    <jats:sub>CMY\u20102\u2010like<\/jats:sub>\n                    n=2). Thirteen dogs carried an\n                    <jats:italic>E. coli<\/jats:italic>\n                    isolate with both an ESBL and a pAmpC gene. One\n                    <jats:italic>E. coli<\/jats:italic>\n                    isolate harboured the human\n                    <jats:italic>bla<\/jats:italic>\n                    <jats:sub>DHA\u20101<\/jats:sub>\n                    pAmpC gene, which has not been previously reported in companion animals in Europe. Dogs with a history of antimicrobial therapy in the past year had a higher risk of being carriers of ESBL\u2010producing (P=0.003, OR =7.85) and pAmpC\u2010producing (P=0.005, OR=6.28)\n                    <jats:italic>E. coli<\/jats:italic>\n                    . Dogs from shelter\/breeders were approximately three times more likely to have an ESBL\u2010 or a pAmpC\u2010producing\n                    <jats:italic>E. coli<\/jats:italic>\n                    than dogs from private owners. Males have a reduced risk of carrying a pAmpC\u2010producing\n                    <jats:italic>E. coli<\/jats:italic>\n                    than females (P=0.017, OR =0.28). The knowledge of potential risk factors may help to limit the impact of resistance through implementation of effective control measures and judicious antimicrobial therapy.\n                  <\/jats:p>","DOI":"10.1136\/vr.101978","type":"journal-article","created":{"date-parts":[[2014,6,19]],"date-time":"2014-06-19T01:08:14Z","timestamp":1403140094000},"page":"202-202","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":43,"title":["Risk factors for faecal colonisation with\n                    <i>Escherichia coli<\/i>\n                    producing extended\u2010spectrum and plasmid\u2010mediated AmpC \u03b2\u2010lactamases in dogs"],"prefix":"10.1002","volume":"175","author":[{"given":"A.","family":"Belas","sequence":"first","affiliation":[{"name":"Laboratory of Antimicrobial and Biocide Resistance, Interdisciplinary Centre of Research in Animal Health, Faculdade de Medicina Veterin\u00e1ria Universidade de Lisboa (FMV\u2010UL) Av. da Universidade T\u00e9cnica \u2013 Polo Universit\u00e1rio Alto da Ajuda 1300\u2010477 Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. S.","family":"Salazar","sequence":"additional","affiliation":[{"name":"Laboratory of Antimicrobial and Biocide Resistance, Interdisciplinary Centre of Research in Animal Health, Faculdade de Medicina Veterin\u00e1ria Universidade de Lisboa (FMV\u2010UL) Av. da Universidade T\u00e9cnica \u2013 Polo Universit\u00e1rio Alto da Ajuda 1300\u2010477 Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. T. da","family":"Gama","sequence":"additional","affiliation":[{"name":"Laboratory of Antimicrobial and Biocide Resistance, Interdisciplinary Centre of Research in Animal Health, Faculdade de Medicina Veterin\u00e1ria Universidade de Lisboa (FMV\u2010UL) Av. da Universidade T\u00e9cnica \u2013 Polo Universit\u00e1rio Alto da Ajuda 1300\u2010477 Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Couto","sequence":"additional","affiliation":[{"name":"Laboratory of Antimicrobial and Biocide Resistance, Interdisciplinary Centre of Research in Animal Health, Faculdade de Medicina Veterin\u00e1ria Universidade de Lisboa (FMV\u2010UL) Av. da Universidade T\u00e9cnica \u2013 Polo Universit\u00e1rio Alto da Ajuda 1300\u2010477 Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Pomba","sequence":"additional","affiliation":[{"name":"Laboratory of Antimicrobial and Biocide Resistance, Interdisciplinary Centre of Research in Animal Health, Faculdade de Medicina Veterin\u00e1ria Universidade de Lisboa (FMV\u2010UL) Av. da Universidade T\u00e9cnica \u2013 Polo Universit\u00e1rio Alto da Ajuda 1300\u2010477 Lisboa Portugal"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,30]]},"reference":[{"key":"e_1_2_7_2_1","unstructured":"AGISAR 2011"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.1.1-14.2004"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01361-09"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/1751-0473-3-17"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.2.833-835.2005"},{"key":"e_1_2_7_7_1","volume-title":"Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals. 3rd edn. 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