{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T15:50:26Z","timestamp":1770220226091,"version":"3.49.0"},"reference-count":25,"publisher":"Wiley","issue":"19","license":[{"start":{"date-parts":[[2015,5,9]],"date-time":"2015-05-09T00:00:00Z","timestamp":1431129600000},"content-version":"vor","delay-in-days":8,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2015,5]]},"abstract":"\n Hypohosphataemia is a frequent finding in early lactating and anorectic dairy cows. Sodium phosphate is commonly used for oral phosphorus (P) supplementation, although other phosphate salts may present useful treatment alternatives. Objectives of this study were to compare the efficacy of monopotassium phosphate (KH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n ) and monocalcium phosphate (Ca(H\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n )\n 2<\/jats:sub>\n ) to monosodium phosphate (NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n ) in P\u2010depleted cows. Furthermore, the effect of concentrated NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n on the reticular groove reflex was studied. Six healthy but P\u2010depleted dairy cows underwent four treatments in randomised order. Treatments consisted of intraruminal administration of NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n , KH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n and Ca(H\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n )\n 2<\/jats:sub>\n providing the equivalent of 60 g P. A fourth treatment consisting of concentrated NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n combined with acetaminophen as a marker substance was administered orally to determine whether the reticular groove reflex could be induced. Intraruminal administration of NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n and KH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n resulted in similar increases in plasma Pi concentrations ([Pi]) while intraruminal Ca(H\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n )\n 2<\/jats:sub>\n resulted in lower increases in plasma [Pi]. Oral and intraruminal administration of NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n resulted in similar times to peak plasma [Pi] and acetaminophen concentration, indicating that concentrated NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n administered orally did not trigger the reticular groove reflex. These results suggest that oral administration of KH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n is equally effective as NaH\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n . Oral administration of Ca(H\n 2<\/jats:sub>\n PO\n 4<\/jats:sub>\n )\n 2<\/jats:sub>\n in contrast has a less pronounced effect on the plasma [Pi].\n <\/jats:p>","DOI":"10.1136\/vr.102847","type":"journal-article","created":{"date-parts":[[2015,2,26]],"date-time":"2015-02-26T22:29:10Z","timestamp":1424989750000},"page":"494-494","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["Enteral administration of monosodium phosphate, monopotassium phosphate and monocalcium phosphate for the treatment of hypophosphataemia in lactating dairy cattle"],"prefix":"10.1002","volume":"176","author":[{"given":"M. J.","family":"Idink","sequence":"first","affiliation":[{"name":"Department of Farm Animal Health Utrecht University Utrecht 3507 TD the Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Gr\u00fcnberg","sequence":"additional","affiliation":[{"name":"Department of Farm Animal Health Utrecht University Utrecht 3507 TD the Netherlands"},{"name":"Clinic for Cattle, University of Veterinary Medicine Hannover, Foundation Hanover Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,5,9]]},"reference":[{"key":"e_1_2_6_2_1","first-page":"A85","article-title":"Magnesium ammonium phosphate precipitation and its significance in sheep","volume":"41","author":"AXFORD R. F. 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C.","year":"1979","journal-title":"Journal of Comparative Pathology"},{"key":"e_1_2_6_10_1","unstructured":"FIELDING C. L.&MAGDESIAN K. G.(2011)Review of packed cell volume and total protein for use in equine practice.Proceedings of the 57th Annual Convention of the American Association of Equine Practitioners San Antonio Texas USA 18\u201322\u00a0November 2011 pp318\u2013321"},{"key":"e_1_2_6_11_1","first-page":"694","article-title":"Testing the P\u2010PILL\u00aephosphorus pill in dairy cows","volume":"91","author":"GEISHAUSER T.","year":"2010","journal-title":"Praktische Tierarzt"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0720(15)30167-5"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.2527\/jas1983.5651214x"},{"key":"e_1_2_6_14_1","unstructured":"GR\u00dcNBERG W.(2008)Phosphorus homeostasis in dairy cattle: some answers more questions.Proceedings of the 17th Annual Tri\u2010State Dairy Nutrition Conference Fort Wayne Indiana USA 22\u201323 April 2008 pp29\u201335"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cvfa.2014.03.002"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0007114513000160"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tvjl.2007.02.023"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.3168\/jds.S0022-0302(86)80445-3"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.2005.66.364"},{"key":"e_1_2_6_20_1","volume-title":"Nutrient Requirements of Dairy Cattle","author":"NRC","year":"2001"},{"key":"e_1_2_6_21_1","doi-asserted-by":"crossref","unstructured":"SATTER L. 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