{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T03:39:57Z","timestamp":1790912397018,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"23","license":[{"start":{"date-parts":[[2015,12,12]],"date-time":"2015-12-12T00:00:00Z","timestamp":1449878400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2015,12]]},"abstract":"<jats:p>\n                    The purpose of this population\u2010based cohort study was to assess current prevalence of antibodies to canine parvovirus (CPV) in adult, healthy dogs, including risk factors associated with lack of antibodies, and reaction to revaccination with a modified live vaccine (MLV). One hundred dogs routinely presented for vaccination were included in the study and vaccinated with a single dose of a combined MLV. Information was collected on signalment, origin, environment, vaccination history and side effects. Prevaccination and postvaccination antibodies were detected by\n                    <jats:italic>haemagglutination<\/jats:italic>\n                    inhibition. Univariate analysis, followed by multivariate logistic regression, was used to investigate association between different variables and presence of antibodies as well as titre increase. Protective CPV antibodies were present in 86.0 per cent of dogs. Intervals of more than four years since the last vaccination and rare contacts with other dogs were determined as main risk factors for the absence of antibodies. An increase in titres only occurred in 17.0 per cent of dogs. Dogs without protective titres before vaccination or with bodyweight &lt;10\u00a0kg were more likely to have an adequate titre increase. Based on these findings, antibody status should be determined instead of periodic vaccinations to ensure reliable protection without unnecessary vaccinations in adult dogs.\n                  <\/jats:p>","DOI":"10.1136\/vr.103271","type":"journal-article","created":{"date-parts":[[2015,10,29]],"date-time":"2015-10-29T23:38:42Z","timestamp":1446161922000},"page":"597-597","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":31,"title":["Prevalence of antibodies to canine parvovirus and reaction to vaccination in client\u2010owned, healthy dogs"],"prefix":"10.1002","volume":"177","author":[{"given":"M.","family":"Riedl","sequence":"first","affiliation":[{"name":"Clinic of Small Animal Medicine, Ludwig\u2010Maximilians\u2010Universitaet of Munich Veterinaerstrasse 13 Munich 80539 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"U.","family":"Truyen","sequence":"additional","affiliation":[{"name":"Institute for Animal Hygiene and Veterinary Public Health, University of Leipzig An den Tierkliniken 1 Leipzig 04103 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Reese","sequence":"additional","affiliation":[{"name":"Department of Veterinary Sciences Institute for Anatomy, Histology and Embryology, Ludwig\u2010Maximilians\u2010Universitaet of Munich Veterinaerstrasse 13 Munich 80539 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Hartmann","sequence":"additional","affiliation":[{"name":"Clinic of Small Animal Medicine, Ludwig\u2010Maximilians\u2010Universitaet of Munich Veterinaerstrasse 13 Munich 80539 Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2015,12,12]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.154.15.457"},{"key":"e_1_2_6_3_1","doi-asserted-by":"crossref","first-page":"784","DOI":"10.2460\/ajvr.1980.41.05.784","article-title":"Hemagglutination by canine parvovirus: serologic studies and diagnostic applications","volume":"41","author":"CARMICHAEL L. 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