{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T22:22:21Z","timestamp":1784067741079,"version":"3.55.0"},"reference-count":32,"publisher":"Wiley","issue":"16","license":[{"start":{"date-parts":[[2016,4,16]],"date-time":"2016-04-16T00:00:00Z","timestamp":1460764800000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","award":["SFRH\/BD\/76291\/2011"],"award-info":[{"award-number":["SFRH\/BD\/76291\/2011"]}],"id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2016,4]]},"abstract":"<jats:p>The authors report a field study that investigated the canine parvovirus (CPV) strains present in dogs that developed the disease after being vaccinated. Faecal samples of 78 dogs that have been vaccinated against CPV and later presented with clinical signs suspected of parvovirus infection were used. Fifty (64.1 per cent) samples tested positive by PCR for CPV. No CPV vaccine type was detected. The disease by CPV\u20102b occurred in older and female dogs when compared with that by CPV\u20102c. The clinical signs presented by infected dogs were similar when any of both variants were involved. In most cases of disease, the resulting infection by field variants occurred shortly after CPV vaccination. Two dogs that had been subjected to a complete vaccination schedule and presented with clinical signs after 10\u00a0days of vaccination, had the CPV\u20102c variant associated. The phylogenetic studies showed a close relationship of the isolates in vaccinated dogs to European field strains. Despite the limited sample size in this study, the findings point to the significance of the continuous molecular typing of the virus as a tool to monitor the prevalent circulating CPV strains and access the efficacy of current vaccines. Adjustments on the vaccine types to be used may have to be evaluated again according to each epidemiological situation in order to achieve the dog's optimal immune protection against CPV.<\/jats:p>","DOI":"10.1136\/vr.103508","type":"journal-article","created":{"date-parts":[[2016,3,9]],"date-time":"2016-03-09T22:58:45Z","timestamp":1457564325000},"page":"397-397","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":18,"title":["Canine parvovirus in vaccinated dogs: a field study"],"prefix":"10.1002","volume":"178","author":[{"given":"C.","family":"Miranda","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinics Instituto de Ci\u00eancias Biom\u00e9dicas de Abel Salazar (ICBAS), Universidade do Porto Porto 4050\u2010313 Portugal"},{"name":"Centro de Investiga\u00e7\u00e3o em Biodiversidade e Recursos Gen\u00e9ticos (CIBIO), InBio, Laborat\u00f3rio Associado, Universidade do Porto Vair\u00e3o 4485\u2010661 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinics Instituto de Ci\u00eancias Biom\u00e9dicas de Abel Salazar (ICBAS), Universidade do Porto Porto 4050\u2010313 Portugal"},{"name":"Centro de Investiga\u00e7\u00e3o em Biodiversidade e Recursos Gen\u00e9ticos (CIBIO), InBio, Laborat\u00f3rio Associado, Universidade do Porto Vair\u00e3o 4485\u2010661 Portugal"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,4,16]]},"reference":[{"key":"e_1_2_7_2_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.06187-11"},{"key":"e_1_2_7_3_1","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-82-12-3021"},{"key":"e_1_2_7_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2010.06.005"},{"key":"e_1_2_7_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2010.00959.x"},{"key":"e_1_2_7_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2011.09.007"},{"key":"e_1_2_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2005.06.004"},{"key":"e_1_2_7_8_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.164.19.593"},{"key":"e_1_2_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.04.050"},{"key":"e_1_2_7_10_1","doi-asserted-by":"publisher","DOI":"10.3201\/eid1308.070505"},{"key":"e_1_2_7_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2006.10.020"},{"key":"e_1_2_7_12_1","first-page":"125","article-title":"Evidence for immunisation failure in vaccinated adult dogs infected with canine parvovirus type 2c","volume":"31","author":"DECARO N.","year":"2008","journal-title":"New Microbiology"},{"key":"e_1_2_7_13_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.3.1718-1726.2003"},{"key":"e_1_2_7_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/1746-6148-8-62"},{"key":"e_1_2_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rvsc.2010.02.013"},{"key":"e_1_2_7_16_1","first-page":"94","article-title":"Do two current parvovirus type 2 and 2b vaccines provide protection against the new type 2c variant?","volume":"9","author":"LARSON L. 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