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The study was performed in three farms with endemic infections with both PRRS virus (PRRSV)\u20101 and PRRSV\u20102, a situation representative of most Korean farms. Pregnant sows were immunised intramuscularly with 2.0\u2009ml of the PRRS subunit vaccine at 58 and 79\u00a0days of gestation (eight and five weeks antepartum) according to the manufacturer's recommendation. Vaccination did not result in any observed adverse reaction. Vaccinated sows exhibited a significant improvement in reproductive performance (reduction of abortions) and litter characteristics (increase of weaned pigs) compared with unvaccinated sows. Vaccinated sows had significantly (P&lt;0.05) higher PRRSV ELISA sample\/positive ratio and number of PRRSV\u2010specific interferon\u2010\u03b3\u2010secreting cells compared with the unvaccinated control group. 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