{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:40:10Z","timestamp":1761864010119,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"23","license":[{"start":{"date-parts":[[2019,12,14]],"date-time":"2019-12-14T00:00:00Z","timestamp":1576281600000},"content-version":"vor","delay-in-days":13,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2019,12]]},"abstract":"<jats:p>Demodicosis is frequently seen in small animal practice. In older dogs, it is often associated with immunosuppression and immunosuppressive diseases. The aim of this study was to evaluate a larger number of dogs with adult\u2010onset demodicosis (AOD) at the veterinary teaching hospitals of the University of Sydney\/Australia and the University of Munich\/Germany. Breed predispositions were compared with the two control populations. Of more than 20\u2009000 dogs and 15\u2009000 in each respective hospital population, 54 dogs in Munich and 68 dogs in Sydney were diagnosed with AOD at a mean age of 8 years. Breed predispositions were seen for West Highland White Terriers in Munich (p&lt;0.0001) and Maltese Terriers and Shih Tzus in Sydney (p&lt;0.01). Concurrent diseases were confirmed in approximately 40% of the dogs both in Munich and Sydney. A significant association was only found between AOD and hyperglucocorticoidism, hypothyroidism and (in Munich) leishmaniosis. Neoplastic diseases were not significantly more common in dogs with demodicosis than in the total population at both locations (p&gt;0.05). Consequently, dogs with AOD should be evaluated for concurrent hyperglucocorticoidism and hypothyroidism, and, in areas of the world where this is prevalent, also for leishmaniosis.<\/jats:p>","DOI":"10.1136\/vr.105388","type":"journal-article","created":{"date-parts":[[2019,8,13]],"date-time":"2019-08-13T17:25:23Z","timestamp":1565717123000},"page":"729-729","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":6,"title":["Is there a correlation between canine adult\u2010onset demodicosis and other diseases?"],"prefix":"10.1002","volume":"185","author":[{"given":"Lisa","family":"Pinsenschaum","sequence":"first","affiliation":[{"name":"Centre for Clinical Veterinary Medicine, University of Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Don Heung Lam","family":"Chan","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine University of Sydney Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linda","family":"Vogelnest","sequence":"additional","affiliation":[{"name":"Faculty of Veterinary Medicine University of Sydney Sydney New South Wales Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karin","family":"Weber","sequence":"additional","affiliation":[{"name":"Centre for Clinical Veterinary Medicine, University of Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5835-5910","authenticated-orcid":false,"given":"Ralf S","family":"Mueller","sequence":"additional","affiliation":[{"name":"Centre for Clinical Veterinary Medicine, University of Munich Munich Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2019,12,14]]},"reference":[{"key":"e_1_2_9_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2002.220.623"},{"key":"e_1_2_9_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-013-3531-z"},{"key":"e_1_2_9_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12001"},{"key":"e_1_2_9_5_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2012.01099.x"},{"key":"e_1_2_9_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2011.01026.x"},{"key":"e_1_2_9_7_1","first-page":"214","article-title":"Hair follicle mites (Demodex spp.) of medical and veterinary concern","volume":"66","author":"Nutting WB","year":"1976","journal-title":"Cornell Vet"},{"key":"e_1_2_9_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/vde.12136"},{"key":"e_1_2_9_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2010.00922.x"},{"key":"e_1_2_9_10_1","doi-asserted-by":"crossref","first-page":"616","DOI":"10.2460\/javma.1994.204.04.616","article-title":"Prognosis for treatment of adult\u2010onset demodicosis in dogs: 34 cases (1979\u20131990)","volume":"204","author":"Duclos DD","year":"1994","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_9_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.1992.tb00178.x"},{"key":"e_1_2_9_12_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2004.00344.x"},{"key":"e_1_2_9_13_1","doi-asserted-by":"crossref","first-page":"1426","DOI":"10.2460\/javma.1993.203.10.1426","article-title":"Clinical efficacy of milbemycin oxime in the treatment of generalized demodicosis in adult dogs","volume":"203","author":"Miller WH","year":"1993","journal-title":"J Am Vet Med Assoc"},{"key":"e_1_2_9_14_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2009.00803.x"},{"key":"e_1_2_9_15_1","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/2016014"},{"key":"e_1_2_9_16_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-015-0775-8"},{"key":"e_1_2_9_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2016.02.027"},{"key":"e_1_2_9_18_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13071-017-2472-2"},{"key":"e_1_2_9_19_1","doi-asserted-by":"publisher","DOI":"10.1053\/jcpa.1998.0273"},{"key":"e_1_2_9_20_1","first-page":"132","article-title":"Daily oral ivermectin for the treatment of generalised demodicosis in 23 dogs","volume":"29","author":"Mueller RS","year":"1999","journal-title":"Aust Vet Pract"},{"key":"e_1_2_9_21_1","first-page":"411","article-title":"La demodecie Du Chien adulte a propos de 22 Cas","volume":"26","author":"Guaguere E","year":"1991","journal-title":"Pratique Medicale and Chirurgicale de l'Animal de Compagnie"},{"key":"e_1_2_9_22_1","first-page":"116","article-title":"Demodicosis (Demodex canis)","volume":"5","author":"Folz SD","year":"1983","journal-title":"Compendium of Continuing Education"},{"key":"e_1_2_9_23_1","first-page":"45","article-title":"Prevalence and pathology of mange\u2010mite infestations","volume":"14","author":"Aujila RS","year":"2000","journal-title":"J Vet Parasitol"},{"key":"e_1_2_9_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetpar.2014.08.021"},{"key":"e_1_2_9_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.2008.00669.x"},{"key":"e_1_2_9_26_1","first-page":"457","volume-title":"Muller & Kirk's small animal dermatology","author":"Scott DW","year":"2001"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.105388","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.105388","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T07:07:52Z","timestamp":1761635272000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.105388"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,12]]},"references-count":25,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2019,12]]}},"alternative-id":["10.1136\/vr.105388"],"URL":"https:\/\/doi.org\/10.1136\/vr.105388","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"type":"print","value":"0042-4900"},{"type":"electronic","value":"2042-7670"}],"subject":[],"published":{"date-parts":[[2019,12]]}}}