{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T18:23:36Z","timestamp":1793298216577,"version":"4.5.0"},"reference-count":30,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T00:00:00Z","timestamp":1602115200000},"content-version":"vor","delay-in-days":7,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2020,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Abnormalities of the ventral lamina of the sixth cervical vertebra (AVL\u2010C6) are thought to exert abnormal stress on the articular process joints (APJs) of the cervicothoracic junction. The aim of the study was to investigate the association between AVL\u2010C6 and radiographic findings in the caudal cervical area and between clinical signs of neck pain and ataxia and radiographic findings.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Medical records of horses subjected to cervical radiography were reviewed. Horses were classified into those with neck pain (group C), those with ataxia (group A) and healthy horses (group H). Presence of AVL\u2010C6 and increased size, dysplasia, remodelling, fragmentation and osteochondral fragment at the APJs (C5\u2013T1) were recorded. Univariable logistic regression analysis was performed to identify the associations between explanatory and dependent variables. Variables with P&lt;0.2 were included in the multivariable analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>One hundred and sixteen horses were included (44\u00a0in group C, 29\u00a0in group A, 66\u00a0in group H); 24 of 116 horses had radiographic AVL\u2010C6. Age, AVL\u2010C6 and overall\/C6\u2013C7\u00a0increase in size remained in the final models.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The presence of AVL\u2010C6 and moderate\/severe increase in size of the caudal cervical APJs increase the odds of showing neck pain and, if severe, ataxia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/vr.105756","type":"journal-article","created":{"date-parts":[[2020,10,8]],"date-time":"2020-10-08T17:21:11Z","timestamp":1602177671000},"update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":23,"title":["Radiographic findings and anatomical variations of the caudal cervical area in horses with neck pain and ataxia: case\u2013control study on 116 horses"],"prefix":"10.1002","volume":"187","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3126-2738","authenticated-orcid":false,"given":"Francesca","family":"Beccati","sequence":"first","affiliation":[{"name":"Sport Horse Research Center, Department of Veterinary Medicine University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco","family":"Pepe","sequence":"additional","affiliation":[{"name":"Sport Horse Research Center, Department of Veterinary Medicine University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Isabella","family":"Santinelli","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rodolfo","family":"Gialletti","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Di Meo","sequence":"additional","affiliation":[{"name":"Department of Veterinary Medicine University of Perugia Perugia Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose Manuel","family":"Romero","sequence":"additional","affiliation":[{"name":"Equivet Veterinarios Madrid Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2020,10,8]]},"reference":[{"key":"e_1_2_11_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118974520.ch6"},{"key":"e_1_2_11_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118974520.ch7"},{"key":"e_1_2_11_4_2","first-page":"531","volume-title":"Clinical radiology of the horse","author":"Butler JA","year":"2017"},{"key":"e_1_2_11_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-1-4160-6069-7.00053-5"},{"key":"e_1_2_11_6_2","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X391015"},{"key":"e_1_2_11_7_2","doi-asserted-by":"publisher","DOI":"10.12968\/ukve.2018.2.2.49"},{"key":"e_1_2_11_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12350"},{"key":"e_1_2_11_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2014.09.012"},{"key":"e_1_2_11_10_2","doi-asserted-by":"publisher","DOI":"10.1111\/evj.12397"},{"key":"e_1_2_11_11_2","doi-asserted-by":"publisher","DOI":"10.1111\/vru.12393"},{"key":"e_1_2_11_12_2","first-page":"1","volume-title":"The topographical anatomy of the head and neck of the horse","author":"Bradley O","year":"1947"},{"key":"e_1_2_11_13_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.75.5.433"},{"key":"e_1_2_11_14_2","first-page":"376","volume-title":"The anatomy of the domestic animals\u2010Volume I","author":"Sisson S","year":"1975"},{"key":"e_1_2_11_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2015.03.002"},{"key":"e_1_2_11_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0278-5919(03)00085-1"},{"key":"e_1_2_11_17_2","doi-asserted-by":"publisher","DOI":"10.1111\/evj.13140"},{"key":"e_1_2_11_18_2","first-page":"1","article-title":"STROBE Statement: linee guida per descrivere gli studi osservazionali [Traduzione Italiana]","volume":"1","author":"Elm E","year":"2008","journal-title":"Terapia Evidence Based"},{"key":"e_1_2_11_19_2","unstructured":"SantinelliI.Valutazione radiografica delle variazioni normali e dell'allineamento delle vertebre cervicali nel cavallo. 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PhD Thesis2015:60\u20134."},{"key":"e_1_2_11_20_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118993712.ch6"},{"key":"e_1_2_11_21_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jevs.2016.09.013"},{"key":"e_1_2_11_22_2","doi-asserted-by":"publisher","DOI":"10.2746\/042516409X434107"},{"key":"e_1_2_11_23_2","doi-asserted-by":"publisher","DOI":"10.21836\/PEM20160308"},{"key":"e_1_2_11_24_2","first-page":"7","volume-title":"Physical therapy and massage for the horse","author":"Denoix JM","year":"2011"},{"key":"e_1_2_11_25_2","first-page":"174","volume-title":"Upper thoracic fixation and hypomobility \u2013 more important than you think. in: North American veterinary conference 2007","author":"Ridgway KJ","year":"2007"},{"key":"e_1_2_11_26_2","doi-asserted-by":"publisher","DOI":"10.1111\/eve.12980"},{"key":"e_1_2_11_27_2","first-page":"199","volume-title":"Equine locomotion","author":"Wolschrijn C","year":"2013"},{"key":"e_1_2_11_28_2","doi-asserted-by":"publisher","DOI":"10.2460\/javma.233.9.1453"},{"key":"e_1_2_11_29_2","doi-asserted-by":"publisher","DOI":"10.1002\/9781118993712.ch28"},{"key":"e_1_2_11_30_2","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.1994.55.01.5"},{"key":"e_1_2_11_31_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0222989"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.105756","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/onlinelibrary.wiley.com\/doi\/full-xml\/10.1136\/vr.105756","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.105756","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.105756","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T11:40:23Z","timestamp":1761565223000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.105756"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10]]},"references-count":30,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,10]]}},"alternative-id":["10.1136\/vr.105756"],"URL":"https:\/\/doi.org\/10.1136\/vr.105756","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"value":"0042-4900","type":"print"},{"value":"2042-7670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,10]]}}}