{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,29]],"date-time":"2025-10-29T06:09:13Z","timestamp":1761718153473,"version":"build-2065373602"},"reference-count":4,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[1998,3,28]],"date-time":"1998-03-28T00:00:00Z","timestamp":891043200000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[1998,3]]},"abstract":"\n Five controlled trials were conducted in Germany or in the United Kingdom, using 74 female sheep of merino or Dorset horn breeds, to evaluate the efficacy of an ivermectin controlled\u2010release capsule against naturally acquired or induced infections of gastrointestinal nematodes, lungworms and nasal bot larvae and against incoming infections with gastrointestinal and pulmonary nematodes. Half of the animals were treated with one ivermectin controlled\u2010release capsule that delivered ivermectin at the rate of 1.6\u00a0mg per day for 100\u00a0days while the other half remained untreated. Parasites were counted 21, 28, 35 or 56\u00a0days after administration of the capsule. The treatment was highly effective (\u226599 per cent) against established parasites of the following species:\n Haemonchus contortus<\/jats:italic>\n (adults and fourth\u2010stage larvae),\n Ostertagia circumcincta, O pinnata, O trifurcata, Ostertagia<\/jats:italic>\n species fourth\u2010stage larvae,\n Trichostrongylus axei, T colubriformis, T vitrinus, Cooperia curticei, Nematodirus battus, N filicollis, Strongyloides papillosus, Chabertia ovina, Oesophagostomum venulosum, Trichuris ovis, Tr skrjabini, Dictyocaulus filaria, Protostrongylus rufescens<\/jats:italic>\n and\n Oestrus ovis<\/jats:italic>\n (larvae). The treatment prevented the establishment of the gastrointestinal nematodes\n H contortus, O circumcincta, T axei, T colubriformnis, C curticei, N battus, N filicoliis, Ch ovina, Oe venulosum<\/jats:italic>\n and the establishment of the lungworm\n D filaria<\/jats:italic>\n by >99 per cent compared with untreated controls (P<0.01).\n <\/jats:p>","DOI":"10.1136\/vr.142.13.331","type":"journal-article","created":{"date-parts":[[2010,10,4]],"date-time":"2010-10-04T23:03:59Z","timestamp":1286233439000},"page":"331-334","source":"Crossref","is-referenced-by-count":17,"title":["Efficacy of an ivermectin controlled\u2010release capsule against nematode and arthropod endoparasites in sheep"],"prefix":"10.1002","volume":"142","author":[{"given":"St.","family":"Rehbein","sequence":"first","affiliation":[{"name":"Biol Merck Research Laboratories Kathrinenhof, Walchenseestrasse 8\u201012 D\u201083101 Rohrdorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. F.","family":"Batty","sequence":"additional","affiliation":[{"name":"Merck Research Laboratories Highfield Farm, Mangrove Lane Hertford SG13 8QJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Barth","sequence":"additional","affiliation":[{"name":"Biol Merck Research Laboratories Kathrinenhof, Walchenseestrasse 8\u201012 D\u201083101 Rohrdorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Visser","sequence":"additional","affiliation":[{"name":"Biol Merck Research Laboratories Kathrinenhof, Walchenseestrasse 8\u201012 D\u201083101 Rohrdorf Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. J.","family":"Timms","sequence":"additional","affiliation":[{"name":"Merck Research Laboratories Highfield Farm, Mangrove Lane Hertford SG13 8QJ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A.","family":"Barrick","sequence":"additional","affiliation":[{"name":"Merck & Company PO Box 2000 Rahway NJ 07065 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. S.","family":"Eagleson","sequence":"additional","affiliation":[{"name":"Merck & Company PO Box 2000 Rahway NJ 07065 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1998,3,28]]},"reference":[{"key":"e_1_2_5_2_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4612-3626-9_15"},{"key":"e_1_2_5_3_1","first-page":"174","volume-title":"Veterin\u00e4rmedizinische Parasitologie","author":"B\u00dcRGER H.\u2010J.","year":"1992"},{"key":"e_1_2_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/0304-4017(95)00862-4"},{"key":"e_1_2_5_5_1","unstructured":"REHBEIN S.(1993) Thesis University of Leipzig"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.142.13.331","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.142.13.331","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T11:01:13Z","timestamp":1761476473000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.142.13.331"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1998,3]]},"references-count":4,"journal-issue":{"issue":"13","published-print":{"date-parts":[[1998,3]]}},"alternative-id":["10.1136\/vr.142.13.331"],"URL":"https:\/\/doi.org\/10.1136\/vr.142.13.331","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"type":"print","value":"0042-4900"},{"type":"electronic","value":"2042-7670"}],"subject":[],"published":{"date-parts":[[1998,3]]}}}