{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T09:31:46Z","timestamp":1789205506911,"version":"build-2803163510"},"reference-count":21,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[1998,5,2]],"date-time":"1998-05-02T00:00:00Z","timestamp":894067200000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[1998,5]]},"abstract":"<jats:p>In August 1995, the first case of porcine dermatitis and nephropathy syndrome was diagnosed in the north\u2010eastern part of Spain; the pig showed characteristic dermal and renal lesions. Between then and January 1996, nine further animals from five different herds were diagnosed; they showed signs of anorexia, depression and, sometimes, pyrexia. Diarrhoea, Gl\u00e4sser's disease, conjunctivitis and gastric ulcers also occurred on the farms where the diagnoses were made. The affected pigs died of renal failure with diffuse fibrinous glomerulonephritis and a systemic necrotising vasculitis. Chronic interstitial nephritis, glomerulosclerosis and scar\u2010like marks on the skin were observed in chronic cases. Other common findings in both acute and chronic cases were a diffuse depletion of lymph node lymphocytes with infiltration by syncytial cells (50 per cent of cases) and interstitial pneumonia. All the animals tested positive for porcine reproductive and respiratory syndrome virus (PRRSV) by serological tests and virus isolation. Serum urea and creatinine concentrations were above normal in the acutely affected animals. The pathogenesis of the condition is unknown but the lesions and immunopathological observations by other authors suggest that a type III hypersensitivity is a possible aetiology. The occurrence of PRRSV in these pigs suggests that the virus might be implicated in the pathogenesis of porcine dermatitis and nephropathy syndrome.<\/jats:p>","DOI":"10.1136\/vr.142.18.483","type":"journal-article","created":{"date-parts":[[2010,10,4]],"date-time":"2010-10-04T23:03:59Z","timestamp":1286233439000},"page":"483-486","source":"Crossref","is-referenced-by-count":43,"title":["Porcine dermatitis and nephropathy syndrome in Spain"],"prefix":"10.1002","volume":"142","author":[{"given":"J.","family":"Segal\u00e9s","sequence":"first","affiliation":[{"name":"Department de Patologia i Producci\u00f3 Animals Facultat de Veterin\u00e1ria Bellattera Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Piella","sequence":"additional","affiliation":[{"name":"Pinsos Baucells SA Tona Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Marco","sequence":"additional","affiliation":[{"name":"Consulting Veterinario Porcino Valldoreix Barcelona Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. 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