{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,2]],"date-time":"2025-11-02T16:32:00Z","timestamp":1762101120820,"version":"build-2065373602"},"reference-count":13,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[1999,6,12]],"date-time":"1999-06-12T00:00:00Z","timestamp":929145600000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[1999,6]]},"abstract":"<jats:p>A masked, randomised, controlled clinical trial for the treatment of canine superficial pyoderma was undertaken. Dogs with a clinical diagnosis of superficial pyoderma, supported by bacterial culture were admitted to the trial and randomly assigned to treatment with either clindamycin hydrochloride at 5.5\u00a0mg\/kg twice daily or clavulanate\u2010amoxycillin at 12.5\u00a0mg\/kg twice daily. After 21\u00a0days the animals were re\u2010assessed, and therapy was continued for a further 21\u00a0days in the dogs with persistent lesions if bacterial culture demonstrated continued sensitivity. Twenty\u2010nine dogs were treated with clindamycin hydrochloride and 27 with clavulanate\u2010amoxycillin. Complete cure was obtained after three weeks in 17 (59 per cent) of the clindamycin\u2010treated cases, but in only eight (30 per cent) of the clavulanate\u2010amoxycillin treated group. Clindamycin was significantly more effective than clavulanate\u2010amoxycillin for the treatment of superficial pyoderma in dogs.<\/jats:p>","DOI":"10.1136\/vr.144.24.662","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T02:05:51Z","timestamp":1286244351000},"page":"662-665","source":"Crossref","is-referenced-by-count":15,"title":["Clindamycin hydrochloride and clavulanate\u2010amoxycillin in the treatment of canine superficial pyoderma"],"prefix":"10.1002","volume":"144","author":[{"given":"D.","family":"Littlewood","sequence":"first","affiliation":[{"name":"Centre for Small Animal Studies Animal Health Trust Lanwades Park, Kentford Newmarket Suffolk CB8 7UU"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. 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