{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T09:34:11Z","timestamp":1761471251858,"version":"build-2065373602"},"reference-count":27,"publisher":"Wiley","issue":"12","license":[{"start":{"date-parts":[[2000,9,16]],"date-time":"2000-09-16T00:00:00Z","timestamp":969062400000},"content-version":"vor","delay-in-days":15,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"MURST"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2000,9]]},"abstract":"<jats:p>An 11\u2010year\u2010old female crossbred dog showed signs of polyuria, polydipsia, vomiting, posterior weakness and ataxia. Clinical and laboratory findings suggested the diagnosis of polycythaemia vera. The haematological values shown over a six\u2010month period are presented. In four samples some aspects of erythrocyte function (glucose\u20106\u2010phosphate dehydrogenase [G6PD] and pyruvate kinase [PK] activities, 2,3 diphosphoglycerate [2,3 DPG] concentration, osomotic fragility and intracellular sodium and potassium concentrations) were studied. Variable activities of G6PD and PK, probably related to different reticulocyte number, were detected together with normal osmotic fragility and intracellular sodium and potassium concentrations. 2,3 DPG concentration was higher than normal in all four samples. This could be interpreted as a response to a low tissue perfusion rather than a higher content of 2,3 DPG in red blood cells from the polycythaemic dog.<\/jats:p>","DOI":"10.1136\/vr.147.12.331","type":"journal-article","created":{"date-parts":[[2010,10,8]],"date-time":"2010-10-08T14:05:40Z","timestamp":1286546740000},"page":"331-334","source":"Crossref","is-referenced-by-count":8,"title":["Some aspects of erythrocyte metabolism in a dog with polycthaemia vera"],"prefix":"10.1002","volume":"147","author":[{"given":"S.","family":"Comazzi","sequence":"first","affiliation":[{"name":"Istituto di Patologia Generale Veterinaria Universita degli Studi di Milano Via Celoria 10 Milan 20133 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Paltrinieri","sequence":"additional","affiliation":[{"name":"Istituto di Patologia Generale Veterinaria Universita degli Studi di Milano Via Celoria 10 Milan 20133 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Agnes","sequence":"additional","affiliation":[{"name":"Istituto di Patologia Generale Veterinaria Universita degli Studi di Milano Via Celoria 10 Milan 20133 Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sacchet","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Elianto Cusano Milanino (MI) Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Milani","sequence":"additional","affiliation":[{"name":"Veterinary Clinic Elianto Cusano Milanino (MI) Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2000,9,16]]},"reference":[{"key":"e_1_2_7_2_1","first-page":"740","article-title":"Adenosine triphosphatase in dog red cells","volume":"12","author":"AGNES F.","year":"1980","journal-title":"La Clinica Veterinaria"},{"key":"e_1_2_7_3_1","first-page":"2709","article-title":"Polycythemia vera and 2,3\u2010diphosphoglycerate deficiency. 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