{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T17:42:19Z","timestamp":1763746939245,"version":"build-2065373602"},"reference-count":33,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2002,9,28]],"date-time":"2002-09-28T00:00:00Z","timestamp":1033171200000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2002,9]]},"abstract":"<jats:p>Between 1995 and 1999, urethral sphincter mechanism incompetence was diagnosed in 11 bitches. They had been treated with phenylpropanolamine hydrochloride at the recommended dose rate, but had shown no response or had become refractory to treatment. They were treated with phenylpropanolamine hydrochloride in a sustained\u2010release formulation combined with diphenylpyraline hydrochloride. The urinary incontinence resolved fully in six of the bitches, two of which remained continent after the treatment was withdrawn; two showed a marked improvement on daily treatment, but the other three bitches failed to respond and underwent colposuspension.<\/jats:p>","DOI":"10.1136\/vr.151.13.373","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T02:27:44Z","timestamp":1286245664000},"page":"373-376","source":"Crossref","is-referenced-by-count":17,"title":["Treatment of urethral sphincter mechanism incompetence in 11 bitches with a sustainedrelease formulation of phenylpropanolamine hydrochloride"],"prefix":"10.1002","volume":"151","author":[{"given":"N. J.","family":"Bacon","sequence":"first","affiliation":[{"name":"Queen's Veterinary School Hospital Department of Clinical Veterinary Medicine University of Cambridge Madingley Road Cambridge CB3 OES"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Oni","sequence":"additional","affiliation":[{"name":"The Veterinary Surgery 20A Kennington Road, Willesborough, Ashford Kent TN24 ONR"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. A. S.","family":"White","sequence":"additional","affiliation":[{"name":"Queen's Veterinary School Hospital Department of Clinical Veterinary Medicine University of Cambridge Madingley Road Cambridge CB3 OES"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2002,9,28]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.2460\/javma.1983.182.11.1212","article-title":"Radiographic and clinical features of pelvic bladder in the dog","volume":"182","author":"ADAMS W. M.","year":"1983","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_8_3_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016487409124646"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.1002\/jps.2600710129"},{"key":"e_1_2_8_5_1","first-page":"332","article-title":"Pelvic floor muscle exercise: 5 years later","volume":"38","author":"CAMMU H.","year":"1995","journal-title":"Urology"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/0378-5173(87)90209-2"},{"key":"e_1_2_8_7_1","doi-asserted-by":"publisher","DOI":"10.3109\/00365597709179701"},{"key":"e_1_2_8_8_1","first-page":"520","volume-title":"Disease Mechanisms in Small Animal Surgery","author":"FENNER W. R.","year":"1993"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0007-1935(05)80222-2"},{"key":"e_1_2_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.130.14.288"},{"key":"e_1_2_8_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.1985.tb02099.x"},{"key":"e_1_2_8_12_1","first-page":"537","article-title":"Longterm evaluation of colposuspension in the treatment of urinary incontinence due to incompetence of the urethral sphincter mechanism in the bitch","volume":"127","author":"HOLT P. E.","year":"1990","journal-title":"Veterinary Record"},{"key":"e_1_2_8_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.133.8.177"},{"key":"e_1_2_8_14_1","first-page":"19","article-title":"Diagnosis and management of canine urethral sphincter mechanism incompetence","volume":"9","author":"HOLT P. E.","year":"1999","journal-title":"Waltham Focus"},{"key":"e_1_2_8_15_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.146.15.437"},{"key":"e_1_2_8_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2510080509"},{"key":"e_1_2_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0090-4295(81)90445-3"},{"key":"e_1_2_8_18_1","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/S0021-5198(19)43508-7","article-title":"Antimuscarinic effects of antihistamines: quantitative evaluation by receptor\u2010binding assay","volume":"42","author":"KUBO N.","year":"1987","journal-title":"Japanese Journal of Pharmacology"},{"key":"e_1_2_8_19_1","first-page":"84","volume-title":"Basic Pharmacology","author":"LASAGNA L.","year":"1988"},{"key":"e_1_2_8_20_1","first-page":"39","article-title":"Steady\u2010state kinetics of sustained\u2010release phenylpropanolamine","volume":"22","author":"L\u00d6NNERHOLM G.","year":"1984","journal-title":"Internal Journal of Clinical Pharmacology, Therapy and Toxicology"},{"key":"e_1_2_8_21_1","first-page":"303","article-title":"Experimental observations on the integration of bladder and urethral function","volume":"15","author":"MCGUIRE E. J.","year":"1978","journal-title":"Investigative Urology"},{"key":"e_1_2_8_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0773.1973.tb01493.x"},{"key":"e_1_2_8_23_1","doi-asserted-by":"crossref","first-page":"691","DOI":"10.2460\/ajvr.1997.58.07.691","article-title":"Simultaneous diuresis cystourethrometry and multi\u2010channel urethral pressure profilometry in female dogs with refractory urinary incontinence","volume":"58","author":"NICKEL R. F.","year":"1997","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_8_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.145.1.11"},{"key":"e_1_2_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(88)50053-0"},{"key":"e_1_2_8_26_1","doi-asserted-by":"publisher","DOI":"10.3109\/02652048909098023"},{"key":"e_1_2_8_27_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1980.tb03094.x"},{"key":"e_1_2_8_28_1","doi-asserted-by":"crossref","first-page":"605","DOI":"10.2460\/javma.1985.187.06.605","article-title":"Clinical response to urethral pressure profile changes after phenylpropanolamine in dogs with primary sphincter incompetence","volume":"187","author":"RICHTER K. P.","year":"1985","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_8_29_1","first-page":"601","article-title":"Diagnosis and pharmacological management of disorders or urinary continence in the dog","volume":"3","author":"ROSIN A. H.","year":"1981","journal-title":"Compendium on Continuing Education for the Practicing Veterinarian"},{"key":"e_1_2_8_30_1","doi-asserted-by":"publisher","DOI":"10.3109\/02652049409040463"},{"key":"e_1_2_8_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2510110703"},{"key":"e_1_2_8_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.321.7272.1326"},{"key":"e_1_2_8_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.1969.tb09946.x"},{"key":"e_1_2_8_34_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.125.19.478"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.151.13.373","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.151.13.373","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T09:09:16Z","timestamp":1761642556000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.151.13.373"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2002,9]]},"references-count":33,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2002,9]]}},"alternative-id":["10.1136\/vr.151.13.373"],"URL":"https:\/\/doi.org\/10.1136\/vr.151.13.373","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"type":"print","value":"0042-4900"},{"type":"electronic","value":"2042-7670"}],"subject":[],"published":{"date-parts":[[2002,9]]}}}