{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T03:40:44Z","timestamp":1790221244940,"version":"4.1.0"},"reference-count":37,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2003,10,4]],"date-time":"2003-10-04T00:00:00Z","timestamp":1065225600000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Racing Victoria and by a Special Virology Fund"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2003,10]]},"abstract":"<jats:p>Five of 10 pregnant, lactating mares, each with a foal at foot, developed neurological disease. Three of them became recumbent, developed complications and were euthanased; of the two that survived, one aborted an equine herpesvirus type 1 (EHV\u20101)\u2010positive fetus 68\u00a0days after the first signs were observed in the index case and the other gave birth to a healthy foal on day 283 but remained ataxic and incontinent. The diagnosis of EHV\u20101\u00a0myeloencephalitis was supported by postmortem findings, PCR identification of the virus and by serological tests with an EHV\u20101 \u2010specific ELISA. At the time of the index case, the 10 foals all had a heavy mucopurulent nasal discharge, and PCR and the ELISA were used to detect and monitor EHV\u20101\u00a0infection in them. The status of EHV\u20101\u00a0infection in the five in\u2010contact mares was similarly monitored. Sera from three of the affected mares, taken seven days after the index case were negative or had borderline EHv\u20101 \u2010specific antibody titres. In later serum samples there was an increase in the titres of EHv\u20101 \u2010specific antibody in two of the affected mares. In contrast, sera from the five unaffected in\u2010contact mares were all EHv\u20101 \u2010antibody positive when they were first tested seven or 13\u00a0days after the index case.<\/jats:p>","DOI":"10.1136\/vr.153.14.417","type":"journal-article","created":{"date-parts":[[2010,10,8]],"date-time":"2010-10-08T13:44:05Z","timestamp":1286545445000},"page":"417-423","source":"Crossref","is-referenced-by-count":43,"title":["Outbreak of equine herpesvirus type 1\u00a0myeloencephalitis: new insights from virus identification by PCR and the application of an EHV\u20101 \u2010specific antibody detection ELISA"],"prefix":"10.1002","volume":"153","author":[{"given":"M. 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