{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T06:02:45Z","timestamp":1761631365187,"version":"build-2065373602"},"reference-count":13,"publisher":"Wiley","issue":"24","license":[{"start":{"date-parts":[[2004,6,12]],"date-time":"2004-06-12T00:00:00Z","timestamp":1086998400000},"content-version":"vor","delay-in-days":11,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2004,6]]},"abstract":"<jats:p>Eight dogs suffered chronic defecation problems characterised by severe dyschezia, manifested by signs of fear and vocalisation on defecation. One or more depigmented, discrete erosions, easily bleeding on palpation, were found in the perineal region. Histopathological changes included interface dermatitis, apoptotic keratinocytes, focal hydropic degeneration of basal epidermal cells, focal thickening of the basement membrane zone and dermal lichenoid infiltrations with mononuclear and plasma cells. A diagnosis of cutaneous or discoid lupus erythematosus was made on the basis of these clinical, physical and specific histopathological changes. The dogs were treated systemically with immunomodulating drugs and good results were obtained.<\/jats:p>","DOI":"10.1136\/vr.154.24.752","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T03:52:48Z","timestamp":1286250768000},"page":"752-754","source":"Crossref","is-referenced-by-count":6,"title":["Dyschezia in dogs with discrete erosive anal disease and histological lesions suggestive of mucocutaneous lupus erythematosus"],"prefix":"10.1002","volume":"154","author":[{"given":"E.","family":"Schrauwen","sequence":"first","affiliation":[{"name":"Dierenartsenpraktijk Plantijn Bosduifstraat 18\/20 B\u20102018 Antwerp Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Junius","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Biology of Small Animals Faculty of Veterinary Medicine, Ghent University Salisburylaan 133 B\u20109820 Merelbeke Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Swinnen","sequence":"additional","affiliation":[{"name":"Dierenartsenpraktijk Venhei Geelsebaan 95\u201097 B\u20102460 Kasterlee Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Maenhout","sequence":"additional","affiliation":[{"name":"Hogeweg 203 B\u20109040 St Amandsberg Belgium"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2004,6,12]]},"reference":[{"key":"e_1_2_5_2_1","first-page":"88","volume-title":"Clinical Immunology of the Dog and Cat","author":"DAY M. J.","year":"1999"},{"key":"e_1_2_5_3_1","first-page":"302","volume-title":"Lupus Erythematosus","author":"DUBOIS E. L.","year":"1987"},{"key":"e_1_2_5_4_1","first-page":"101","article-title":"Lupus eryth\u00e9mateux disco\u00efde \u00e0 localisation auriculaire chez le chien","volume":"24","author":"GUAGU\u00c8RE E.","year":"1989","journal-title":"Pratique M\u00e9dicale et Chirurgicale de l'Animal de Compagnie"},{"key":"e_1_2_5_5_1","first-page":"129","volume-title":"Textbook of Veterinary Internal Medicine","author":"JONES B.","year":"2000"},{"key":"e_1_2_5_6_1","first-page":"7","article-title":"Discoid lupus erythematosus in a cat","volume":"19","author":"KALAHER K. M.","year":"1991","journal-title":"Feline Practice"},{"key":"e_1_2_5_7_1","unstructured":"OLIVRY T.(2000)Cutaneous manifestations of lupus in humans and dogs. Proceedings of theesvdWorkshop on Immunodermatology. Saint\u2010Paul de Vence France March 23 to 26 2000. pp1\u20134"},{"key":"e_1_2_5_8_1","first-page":"205","article-title":"Le lupus eryth\u00e9mateux disco\u00efde du chien a propos de 22 observations","volume":"22","author":"OLIVRY T.","year":"1987","journal-title":"Pratique M\u00e9dicale et Chirurgicale de l'Animal de Compagnie"},{"key":"e_1_2_5_9_1","unstructured":"ROSENBAUM M.(1999)Cyclosporine application in small animal dermatology.Newsletter of the American Academy of Veterinary Dermatology and American College of Veterinary DermatologySummer 5\u20137"},{"key":"e_1_2_5_10_1","first-page":"377","article-title":"Clinical evaluation of cyclosporine in animal models with cutaneous immune\u2010mediated disease and epitheliotrophic lymphoma","volume":"25","author":"ROSENKRANTZ W. S.","year":"1989","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_5_11_1","first-page":"481","article-title":"Canine lupus erythematosus. II: Discoid lupus erythematosus","volume":"19","author":"SCOTT D. W.","year":"1983","journal-title":"Journal of the American Animal Hospital Association"},{"key":"e_1_2_5_12_1","first-page":"704","volume-title":"Muller & Kirk's Small Animal Dermatology","author":"SCOTT D. W.","year":"2000"},{"key":"e_1_2_5_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-3164.1990.tb00071.x"},{"key":"e_1_2_5_14_1","first-page":"31","volume-title":"European Society of Veterinary Dermatology","author":"YAGER J. A.","year":"2001"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.154.24.752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.154.24.752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:58:38Z","timestamp":1761631118000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.154.24.752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,6]]},"references-count":13,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2004,6]]}},"alternative-id":["10.1136\/vr.154.24.752"],"URL":"https:\/\/doi.org\/10.1136\/vr.154.24.752","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"type":"print","value":"0042-4900"},{"type":"electronic","value":"2042-7670"}],"subject":[],"published":{"date-parts":[[2004,6]]}}}