{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T14:29:12Z","timestamp":1787668152400,"version":"build-2736575974"},"reference-count":24,"publisher":"Wiley","issue":"13","license":[{"start":{"date-parts":[[2004,9,25]],"date-time":"2004-09-25T00:00:00Z","timestamp":1096070400000},"content-version":"vor","delay-in-days":24,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"name":"Wellcome Trust, the Royal College of Veterinary Surgeons (Wilson) Scholarship in Production Animal Medicine"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2004,9]]},"abstract":"<jats:p>\n                    The minimum inhibitory concentrations (MICs) of oxytetracycline, cephapirin, cephapirin\/mecillinam, cefquinome, ceftiofur and enrofloxacin, candidate antibiotics for the principal bacteria associated with uterine infections:\n                    <jats:italic>Escherichia coli<\/jats:italic>\n                    ,\n                    <jats:italic>Arcanobacterium pyogenes<\/jats:italic>\n                    and the anaerobic bacteria\n                    <jats:italic>Fusobacterium necrophorum<\/jats:italic>\n                    and\n                    <jats:italic>Prevotella melaninogenicus<\/jats:italic>\n                    , were determined by the agar dilution method. The bacteria were isolated from animals with clinical metritis and\/or endometritis. For\n                    <jats:italic>E coli<\/jats:italic>\n                    , cefquinome and enrofloxacin had the lowest MIC90 and MIC50 values (&lt;0.06 \u03bcg\/ml), and oxytetracycline and cephapirin had the highest values. For\n                    <jats:italic>A pyogenes<\/jats:italic>\n                    , oxytetracycline had the highest MIC50 value (16 \u03bcg\/ml), but all the cephalosporins had values below 0.06 \u03bcg\/ml. For the anaerobic bacteria, enrofloxacin and oxytetracycline had the highest MIC50 values but all the cephalosporins had values of 0.06 \u03bcg\/ml or below.\n                  <\/jats:p>","DOI":"10.1136\/vr.155.13.383","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T03:52:48Z","timestamp":1286250768000},"page":"383-387","source":"Crossref","is-referenced-by-count":75,"title":["Minimum inhibitory concentrations of some antimicrobial drugs against bacteria causing uterine infections in cattle"],"prefix":"10.1002","volume":"155","author":[{"given":"I. M.","family":"Sheldon","sequence":"first","affiliation":[{"name":"Department of Veterinary Clinical Sciences Hawkshead Lane Hatfield AL9 7TA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Bushnell","sequence":"additional","affiliation":[{"name":"Department of Pathology and Infectious Diseases, Royal Veterinary College Hawkshead Lane Hatfield AL9 7TA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Montgomery","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences Hawkshead Lane Hatfield AL9 7TA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. N.","family":"Rycroft","sequence":"additional","affiliation":[{"name":"Department of Pathology and Infectious Diseases, Royal Veterinary College Hawkshead Lane Hatfield AL9 7TA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2004,9,25]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1017\/CBO9780511527104.007"},{"key":"e_1_2_6_3_1","first-page":"168","article-title":"Endometrial biopsy in Holstein\u2010Friesian dairy cows. III. Bacteriological analysis and correlations with histological findings","volume":"55","author":"BONNETT B. M.","year":"1991","journal-title":"Canadian Journal of Veterinary Research"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.124.9.217"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-0720(15)31132-4"},{"key":"e_1_2_6_6_1","doi-asserted-by":"crossref","first-page":"764","DOI":"10.2460\/ajvr.1983.44.05.764","article-title":"Distribution of oxytetracycline in genital tract tissues of postpartum cows given the drug by intravenous and intrauterine routes","volume":"44","author":"BRETZLAFF K. N.","year":"1983","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(82)90178-9"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(95)00124-Q"},{"key":"e_1_2_6_9_1","first-page":"77","article-title":"Uterus of the cow after parturition: bacterial content","volume":"29","author":"ELLIOT L.","year":"1968","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.47.3.361-409.1983"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(74)90052-1"},{"key":"e_1_2_6_12_1","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.2460\/javma.1984.185.10.1194","article-title":"Therapeutic strategies involving antimicrobial treatment of the uterus in large animals","volume":"185","author":"GUSTAFSSON B. K.","year":"1984","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.144.16.437"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1090-0233(05)80007-3"},{"key":"e_1_2_6_15_1","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/jac\/23.3.353","article-title":"In\u2010vitro susceptibility of nosocomial Gram\u2010negative bloodstream pathogens to quinolones and other antibiotics \u2013 a statistical approach","volume":"23","author":"MARTIN M. A.","year":"1989","journal-title":"Journal of Antimicrobial Chemotherapy"},{"key":"e_1_2_6_16_1","volume-title":"Dairy Facts and Figures","author":"NATIONAL DAIRY COUNCIL","year":"2000"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.124.21.563"},{"key":"e_1_2_6_18_1","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.2460\/ajvr.1984.45.11.2251","article-title":"Aspects of bacteriology and endocrinology of cows with pyometra and retained foetal membranes","volume":"45","author":"OLSON J. D.","year":"1984","journal-title":"American Journal of Veterinary Research"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0093-691X(81)90060-1"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/0007-1935(92)90087-H"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.142.21.575"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.1530\/rep.0.1230837"},{"key":"e_1_2_6_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.154.10.289"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/vr.128.7.147"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0950268800050925"}],"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.155.13.383","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.155.13.383","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T11:44:42Z","timestamp":1761565482000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.155.13.383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,9]]},"references-count":24,"journal-issue":{"issue":"13","published-print":{"date-parts":[[2004,9]]}},"alternative-id":["10.1136\/vr.155.13.383"],"URL":"https:\/\/doi.org\/10.1136\/vr.155.13.383","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"value":"0042-4900","type":"print"},{"value":"2042-7670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004,9]]}}}