{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T07:11:55Z","timestamp":1776755515561,"version":"3.51.2"},"reference-count":0,"publisher":"Wiley","issue":"17","license":[{"start":{"date-parts":[[2007,4,28]],"date-time":"2007-04-28T00:00:00Z","timestamp":1177718400000},"content-version":"vor","delay-in-days":27,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2007,4]]},"abstract":"<jats:p>Six domestic shorthair cats, aged three to four years and weighing 5\u00b71 to 7\u00b74\u00a0kg, were used to assess the thermal antinociceptive effect of a transdermal buprenorphine patch, designed to supply 35 \u03bcg buprenorphine\/hour, which was applied to the shaved thorax. The cats' thermal thresholds were tested before the patch was applied and two, four, six, eight, 10, 12, 14 and 16 hours after it had been applied, and then every six hours until it was removed after 72 hours, and for a further 24 hours afterwards. Blood was collected at each time to measure the plasma concentration of buprenorphine. The patches did not produce a significant change in the thermal thresholds of the cats throughout the testing period. The mean (sd) peak plasma buprenorphine concentration was 10 (0\u00b781) ng\/ml.<\/jats:p>","DOI":"10.1136\/vr.160.17.578","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T05:01:32Z","timestamp":1286254892000},"page":"578-583","source":"Crossref","is-referenced-by-count":50,"title":["Use of a transdermal matrix patch of buprenorphine in cats: preliminary pharmacokinetic and pharmacodynamic data"],"prefix":"10.1002","volume":"160","author":[{"given":"J. C.","family":"Murrell","sequence":"first","affiliation":[{"name":"Faculty of Veterinary Medicine University of Utrecht Utrecht The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. A.","family":"Robertson","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine University of Florida PO Box 100136 Gainesville FL 32610 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. M.","family":"Taylor","sequence":"additional","affiliation":[{"name":"Taylor Monroe, Downham Common, Little Downham Ely Cambridgeshire CB6 2TY"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. L.","family":"McCown","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine University of Florida PO Box 100136 Gainesville FL 32610 USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Bloomfield","sequence":"additional","affiliation":[{"name":"Department of Clinical Veterinary Medicine University of Cambridge Madingley Road Cambridge CB3 0ES"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. W.","family":"Sear","sequence":"additional","affiliation":[{"name":"Nuffield Department of Anaesthetics University of Oxford Radcliffe Infirmary Woodstock Road Oxford OX2 6HE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,4,28]]},"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.160.17.578","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.160.17.578","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:20:25Z","timestamp":1761560425000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.160.17.578"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,4]]},"references-count":0,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2007,4]]}},"alternative-id":["10.1136\/vr.160.17.578"],"URL":"https:\/\/doi.org\/10.1136\/vr.160.17.578","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"value":"0042-4900","type":"print"},{"value":"2042-7670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,4]]}}}