{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,7]],"date-time":"2026-02-07T03:41:27Z","timestamp":1770435687822,"version":"3.49.0"},"reference-count":0,"publisher":"Wiley","issue":"20","license":[{"start":{"date-parts":[[2007,5,19]],"date-time":"2007-05-19T00:00:00Z","timestamp":1179532800000},"content-version":"vor","delay-in-days":18,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2007,5]]},"abstract":"<jats:p>\n                    Sixty\u2010four dogs were randomly assigned to receive either thiopentone or propofol and their electrocardiograms were recorded immediately before and shortly after they were anaesthetised. Thiopentone caused a marked increase in\n                    <jats:sc>qt<\/jats:sc>\n                    and\n                    <jats:sc>jt<\/jats:sc>\n                    intervals, a flattening of the T\u2010wave and an increase in precordial\n                    <jats:sc>qt<\/jats:sc>\n                    dispersion. Propofol induced a less marked increase in\n                    <jats:sc>qt<\/jats:sc>\n                    and\n                    <jats:sc>jt<\/jats:sc>\n                    intervals, corrected for heart rate. Both agents induced an increase in heart rate and a decrease in heart rate variability, consistent with reduced vagal tone. Shortly after anaesthesia was induced, thiopentone affected ventricular repolarisation to a far greater extent than propofol, changes which suggest that it may be more likely to induce re\u2010entrant ventricular arrhythmogenesis and could be associated with an increase in sympathetic tone. Propofol may therefore be more suitable than thiopentone for dogs with a susceptibility to ventricular arrhythmias or a long\n                    <jats:sc>qt<\/jats:sc>\n                    interval.\n                  <\/jats:p>","DOI":"10.1136\/vr.160.20.681","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T05:01:32Z","timestamp":1286254892000},"page":"681-686","source":"Crossref","is-referenced-by-count":9,"title":["Comparison of the effects of thiopentone and propofol on the electrocardiogram of dogs"],"prefix":"10.1002","volume":"160","author":[{"given":"S. G.","family":"Dennis","sequence":"first","affiliation":[{"name":"Division of Small Animal Clinical Studies Faculty of Veterinary Medicine University of Glasgow Veterinary School Bearsden Road Bearsden Glasgow G61 1QH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. R.","family":"Wotton","sequence":"additional","affiliation":[{"name":"Division of Small Animal Clinical Studies Faculty of Veterinary Medicine University of Glasgow Veterinary School Bearsden Road Bearsden Glasgow G61 1QH"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Boswood","sequence":"additional","affiliation":[{"name":"Department of Veterinary Clinical Sciences Royal Veterinary College Hawkshead Lane, North Mymms Hatfield Hertfordshire AL9 7TA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Flaherty","sequence":"additional","affiliation":[{"name":"Division of Small Animal Clinical Studies Faculty of Veterinary Medicine University of Glasgow Veterinary School Bearsden Road Bearsden Glasgow G61 1QH"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2007,5,19]]},"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.160.20.681","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.160.20.681","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T11:43:44Z","timestamp":1761651824000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.160.20.681"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":0,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["10.1136\/vr.160.20.681"],"URL":"https:\/\/doi.org\/10.1136\/vr.160.20.681","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"value":"0042-4900","type":"print"},{"value":"2042-7670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}