{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,3]],"date-time":"2026-08-03T12:52:20Z","timestamp":1785761540349,"version":"3.56.0"},"reference-count":0,"publisher":"Wiley","issue":"25","license":[{"start":{"date-parts":[[2007,6,23]],"date-time":"2007-06-23T00:00:00Z","timestamp":1182556800000},"content-version":"vor","delay-in-days":22,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p>\n                    Allergen\u2010specific immunotherapy (\n                    <jats:sc>asit<\/jats:sc>\n                    ) is one of the main treatments for atopic dermatitis in dogs, but it often requires additional treatments such as antibacterial and antifungal therapy for secondary bacterial and yeast infections, or antipruritic drugs to control the clinical signs or treat the adverse effects of the immunotherapy. Twenty\u2010seven dogs enrolled in a study of\n                    <jats:sc>asit<\/jats:sc>\n                    were clinically assessed four times over a period of nine months; their requirement for treatment for secondary bacterial and yeast infections, for the administration of glucocorticoids as additional antipruritic therapy, and for the treatment of any adverse effects of the\n                    <jats:sc>asit<\/jats:sc>\n                    were evaluated. Twenty (74 per cent) of the dogs were treated for superficial bacterial pyoderma, 18 (66\u00b76 per cent) required treatment for\n                    <jats:italic>Malassezia<\/jats:italic>\n                    species dermatitis on one or more occasions, eight (29\u00b76 per cent) required treatment for otitis externa due to\n                    <jats:italic>Malassezia<\/jats:italic>\n                    species or bacteria, and eight required glucocorticoids to control their clinical signs. Five (18\u00b75 per cent) of the dogs experienced adverse effects due to the\n                    <jats:sc>asit<\/jats:sc>\n                    and two required treatment with antihistamines (H1 receptor antagonists) in order to continue with the\n                    <jats:sc>asit<\/jats:sc>\n                    .\n                  <\/jats:p>","DOI":"10.1136\/vr.160.25.861","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T05:01:32Z","timestamp":1286254892000},"page":"861-864","source":"Crossref","is-referenced-by-count":13,"title":["Requirement for additional treatment for dogs with atopic dermatitis undergoing allergen\u2010specific immunotherapy"],"prefix":"10.1002","volume":"160","author":[{"given":"S.","family":"Colombo","sequence":"first","affiliation":[{"name":"Dermatology Unit Division of Veterinary Clinical Sciences Royal (Dick) School of Veterinary Studies University of Edinburgh Easter Bush Veterinary Centre Roslin Midlothian EH25 9RG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"P. B.","family":"Hill","sequence":"additional","affiliation":[{"name":"Dermatology Unit Division of Veterinary Clinical Sciences Royal (Dick) School of Veterinary Studies University of Edinburgh Easter Bush Veterinary Centre Roslin Midlothian EH25 9RG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. J.","family":"Shaw","sequence":"additional","affiliation":[{"name":"Hospital for Small Animals Division of Veterinary Clinical Sciences Royal (Dick) School of Veterinary Studies University of Edinburgh Easter Bush Veterinary Centre Roslin Midlothian EH25 9RG"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K. L.","family":"Thoday","sequence":"additional","affiliation":[{"name":"Dermatology Unit Division of Veterinary Clinical Sciences Royal (Dick) School of Veterinary Studies University of Edinburgh Easter Bush Veterinary Centre Roslin Midlothian EH25 9RG"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2007,6,23]]},"container-title":["Veterinary Record"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1136%2Fvr.160.25.861","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1136\/vr.160.25.861","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T10:34:46Z","timestamp":1761561286000},"score":1,"resource":{"primary":{"URL":"https:\/\/bvajournals.onlinelibrary.wiley.com\/doi\/10.1136\/vr.160.25.861"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":0,"journal-issue":{"issue":"25","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1136\/vr.160.25.861"],"URL":"https:\/\/doi.org\/10.1136\/vr.160.25.861","archive":["Portico"],"relation":{},"ISSN":["0042-4900","2042-7670"],"issn-type":[{"value":"0042-4900","type":"print"},{"value":"2042-7670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}