{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T15:02:30Z","timestamp":1791644550372,"version":"4.3.4"},"reference-count":33,"publisher":"Wiley","issue":"14","license":[{"start":{"date-parts":[[2008,10,4]],"date-time":"2008-10-04T00:00:00Z","timestamp":1223078400000},"content-version":"vor","delay-in-days":3,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2008,10]]},"abstract":"<jats:p>\n                    Leptospirosis is a bacterial disease affecting several mammalian species, including human beings. In dogs, it is spread mainly by rodents that act as a maintenance host for several\n                    <jats:italic>Leptospira<\/jats:italic>\n                    serovars. Until recently, the most common signs observed in affected dogs consisted of icterus and haemorrhagic diathesis, but today the most prevalent clinical signs are attributed to acute renal failure. The current literature gives a good review of leptospirosis in dogs in the\n                    <jats:sc>usa<\/jats:sc>\n                    and Canada, but less information is available about its occurrence in Europe. This review considers the clinical signs, diagnosis, treatment and prevention of this emerging zoonotic disease.\n                  <\/jats:p>","DOI":"10.1136\/vr.163.14.409","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T17:36:25Z","timestamp":1286300185000},"page":"409-413","source":"Crossref","is-referenced-by-count":46,"title":["Leptospirosis in dogs: a review with emphasis on clinical aspects"],"prefix":"10.1002","volume":"163","author":[{"given":"I.","family":"van de Maele","sequence":"first","affiliation":[{"name":"Department of Medicine and Clinical Biology of Small Animals Ghent University Salisburylaan 133 9820 Merelbeke Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Claus","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Biology of Small Animals Ghent University Salisburylaan 133 9820 Merelbeke Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Haesebrouck","sequence":"additional","affiliation":[{"name":"Department of Pathology, Bacteriology and Poultry Diseases Faculty of Veterinary Medicine Ghent University Salisburylaan 133 9820 Merelbeke Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Daminet","sequence":"additional","affiliation":[{"name":"Department of Medicine and Clinical Biology of Small Animals Ghent University Salisburylaan 133 9820 Merelbeke Belgium"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,10,4]]},"reference":[{"key":"e_1_2_8_2_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2000.216.371"},{"key":"e_1_2_8_3_1","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/9780470344903.ch28","volume-title":"Pathogenesis of Bacterial Infections in Animals","author":"Adler B.","year":"2004"},{"key":"e_1_2_8_4_1","doi-asserted-by":"publisher","DOI":"10.2460\/javma.2001.219.636"},{"key":"e_1_2_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2006.04.005"},{"key":"e_1_2_8_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1740-8261.2001.tb00944.x"},{"key":"e_1_2_8_7_1","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1016\/j.femsle.2005.01.007","article-title":"Polymerase chain reaction assay specific for pathogenic Leptospira based on the gene hap 1 encoding the hemolysis\u2010associated protein\u20101","volume":"15","author":"Branger C.","year":"2005","journal-title":"FEMS Microbiology Letters"},{"key":"e_1_2_8_8_1","doi-asserted-by":"crossref","first-page":"259","DOI":"10.21825\/vdt.87217","article-title":"Leptospirosis in dogs: a retrospective study of seven clinical cases in Belgium","volume":"77","author":"Claus A.","year":"2008","journal-title":"Vlaams Diergeneeskundig Tijdschrift"},{"key":"e_1_2_8_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0195-5616(00)05009-9"},{"key":"e_1_2_8_10_1","first-page":"691","volume-title":"Diseases of Swine","author":"Ellis W. 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