{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T12:08:18Z","timestamp":1791374898919,"version":"4.3.1"},"reference-count":48,"publisher":"Wiley","issue":"18","license":[{"start":{"date-parts":[[2009,5,2]],"date-time":"2009-05-02T00:00:00Z","timestamp":1241222400000},"content-version":"vor","delay-in-days":1,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"funder":[{"DOI":"10.13039\/501100004379","name":"Swedish Farmers\u2019 Foundation for Agricultural Research","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100004379","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Veterinary Record"],"published-print":{"date-parts":[[2009,5]]},"abstract":"<jats:p>\n                    Four groups of six specific pathogen\u2010free (SPF) pigs were inoculated intranasally with\n                    <jats:italic>Actinobacillus pleuropneumoniae<\/jats:italic>\n                    serotype 2 and treated with either enrofloxacin, tetracycline or penicillin at the onset of clinical disease, or left untreated. A fifth group was left uninoculated. The inoculated control and the penicillin\u2010treated groups developed severe disease, but the groups treated with enrofloxacin and tetracycline recovered rapidly. All the inoculated pigs, except those treated with enrofloxacin developed serum antibodies to\n                    <jats:italic>A pleuropneumoniae<\/jats:italic>\n                    . On day 28, all five groups were challenged with\n                    <jats:italic>A pleuropneumoniae<\/jats:italic>\n                    without any subsequent treatment. The previously uninoculated control group and the enrofloxacin\u2010treated group developed severe disease, but the three seropositive groups remained unaffected.\n                  <\/jats:p>","DOI":"10.1136\/vr.164.18.550","type":"journal-article","created":{"date-parts":[[2010,10,5]],"date-time":"2010-10-05T17:44:04Z","timestamp":1286300644000},"page":"550-555","source":"Crossref","is-referenced-by-count":17,"title":["Responses of pigs to a re\u2010challenge with\n                    <i>Actinobacillus pleuropneumoniae<\/i>\n                    after being treated with different antimicrobials following their initial exposure"],"prefix":"10.1002","volume":"164","author":[{"given":"M.","family":"Sj\u00f6lund","sequence":"first","affiliation":[{"name":"National Veterinary Institute Department of Animal Health and Antimicrobial Strategies SE\u2010751 89 Uppsala Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. 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