{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T04:03:46Z","timestamp":1789704226010,"version":"4.0.1"},"reference-count":33,"publisher":"BMJ","issue":"4","license":[{"start":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T00:00:00Z","timestamp":1700524800000},"content-version":"unspecified","delay-in-days":20,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["World Jnl Ped Surgery"],"published-print":{"date-parts":[[2023,11]]},"abstract":"<jats:sec><jats:title>Objective<\/jats:title><jats:p>Postoperative pulmonary complications (PPCs) are an important quality indicator and are associated with significantly increased mortality in infants. The objective of this study was to identify risk factors for PPCs in neonates undergoing non-cardiothoracic surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Methods<\/jats:title><jats:p>In this retrospective study, all neonates who underwent non-cardiothoracic surgery in a children\u2019s hospital from October 2020 to September 2022 were included for analysis. Demographic data and perioperative variables were obtained. The primary outcome was the occurrence of PPCs. Univariate analysis and multivariable logistic regression analysis were used to investigate the effect of patient-related factors on the occurrence of PPCs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>Totally, 867 neonatal surgery patients met the inclusion criteria in this study, among which 35.3% (306\/867) patients experienced pulmonary complications within 1\u2009week postoperatively. The PPCs observed in this study were 51 exacerbations of pre-existing pneumonia, 198 new patchy shadows, 123 new pulmonary atelectasis, 10 new pneumothorax, and 6 new pleural effusion. Patients were divided into two groups: PPCs (n=306) and non-PPCs (n=561). The multivariate stepwise logistic regression analysis revealed five independent risk factors for PPCs: corrected gestational age (OR=0.938; 95% CI 0.890 to 0.988), preoperative pneumonia (OR=2.139; 95% CI 1.033 to 4.426), length of surgery (&gt; 60\u2009min) (OR=1.699; 95% CI 1.134 to 2.548), preoperative mechanical ventilation (OR=1.857; 95% CI 1.169 to 2.951), and intraoperative albumin infusion (OR=1.456; 95% CI 1.041 to 2.036) in neonates undergoing non-cardiothoracic surgery.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion<\/jats:title><jats:p>Identifying risk factors for neonatal PPCs will allow for the identification of patients who are at higher risk and intervention for any modifiable risk factors identified.<\/jats:p><\/jats:sec>","DOI":"10.1136\/wjps-2023-000657","type":"journal-article","created":{"date-parts":[[2023,11,21]],"date-time":"2023-11-21T17:35:30Z","timestamp":1700588130000},"page":"e000657","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":8,"title":["Risk factors for postoperative pulmonary complications in neonates: a retrospective cohort study"],"prefix":"10.1136","volume":"6","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-5943-5957","authenticated-orcid":false,"given":"Bin Bin","family":"Cai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Pi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2023,11,21]]},"reference":[{"key":"2023112109350499000_6.4.e000657.1"},{"key":"2023112109350499000_6.4.e000657.2","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/anae.13311","article-title":"Peri-operative pulmonary dysfunction and protection","volume":"71 Suppl 1","author":"Marseu","year":"2016","journal-title":"Anaesthesia"},{"key":"2023112109350499000_6.4.e000657.3","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.bpa.2020.04.011","article-title":"Perioperative strategies for the reduction of postoperative pulmonary complications","volume":"34","author":"Chandler","year":"2020","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"2023112109350499000_6.4.e000657.4","first-page":"333","article-title":"Risk factors for postoperative pulmonary complications and prolonged hospital stay in pulmonary resection patients: a retrospective study","volume":"71","author":"Bevilacqua Filho","year":"2021","journal-title":"Braz J Anesthesiol"},{"key":"2023112109350499000_6.4.e000657.5","doi-asserted-by":"crossref","first-page":"371","DOI":"10.23736\/S0375-9393.20.14411-0","article-title":"Simple is better: looking for a clinical prognostic tool for risk assessment of postoperative pulmonary complications after abdominal surgery","volume":"86","author":"Piccioni","year":"2020","journal-title":"Minerva Anestesiol"},{"key":"2023112109350499000_6.4.e000657.6","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1213\/ANE.0000000000005246","article-title":"Perioperative lung protection: general mechanisms and protective approaches","volume":"131","author":"Ball","year":"2020","journal-title":"Anesth Analg"},{"key":"2023112109350499000_6.4.e000657.7"},{"key":"2023112109350499000_6.4.e000657.8","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.123083"},{"key":"2023112109350499000_6.4.e000657.9","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.09154"},{"key":"2023112109350499000_6.4.e000657.10","doi-asserted-by":"publisher","DOI":"10.1016\/j.bja.2018.02.007"},{"key":"2023112109350499000_6.4.e000657.11","doi-asserted-by":"crossref","unstructured":"Egbuta C , Mason KP . 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