{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,15]],"date-time":"2026-04-15T02:31:32Z","timestamp":1776220292593,"version":"3.50.1"},"reference-count":68,"publisher":"BMJ","issue":"1","license":[{"start":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T00:00:00Z","timestamp":1767744000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["World Jnl Ped Surgery"],"accepted":{"date-parts":[[2025,10,19]]},"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>\n                    Biliary atresia (BA) is a progressive cholangiopathy of infancy and the leading cause of pediatric liver transplantation. Despite surgical intervention with the Kasai portoenterostomy, long-term outcomes remain poor, with many patients progressing to cirrhosis. Emerging evidence implicates the gut microbiota\u2014a dynamic ecosystem crucial to immune development and liver homeostasis\u2014in BA pathogenesis and clinical progression. This review synthesizes current literature on gut microbiota composition in BA before and after the Kasai procedure, highlighting consistent patterns of dysbiosis, including pathobiont expansion and depletion of beneficial microbes such as\n                    <jats:italic>Bifidobacterium<\/jats:italic>\n                    . The review explores associations between microbial profiles and clinical outcomes\u2014highlighting potential mechanisms involving bile acid metabolism, microbial translocation, and immune modulation. Further understanding of gut\u2013liver\u2013microbiota interactions in BA may inform microbiome-targeted therapies to improve native liver survival.\n                  <\/jats:p>","DOI":"10.1136\/wjps-2025-001068","type":"journal-article","created":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T12:50:36Z","timestamp":1767790236000},"page":"e001068","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":2,"title":["Gut microbiome in biliary atresia"],"prefix":"10.1136","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-0907-4718","authenticated-orcid":false,"given":"Vandana","family":"Jain","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"239","published-online":{"date-parts":[[2026,1,7]]},"reference":[{"key":"2026010704503145000_9.1.e001068.1","doi-asserted-by":"crossref","first-page":"1704","DOI":"10.1016\/S0140-6736(09)60946-6","article-title":"Biliary 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