{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T13:34:17Z","timestamp":1786541657121,"version":"build-2736575974"},"reference-count":23,"publisher":"BMJ","issue":"4","license":[{"start":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T00:00:00Z","timestamp":1786492800000},"content-version":"unspecified","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100000272","name":"National Institute for Health and Care Research","doi-asserted-by":"publisher","award":["nihr24005"],"award-info":[{"award-number":["nihr24005"]}],"id":[{"id":"10.13039\/501100000272","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["World Jnl Ped Surgery"],"accepted":{"date-parts":[[2026,7,20]]},"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Congenital birth defects contribute substantially to child mortality in the Global South. From the caregiver perspective, we aim to describe the timing of diagnosis of children with structural birth defects, where diagnosis is delayed, and the underlying reasons.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A cross-sectional study of children with structural birth defects at three public hospitals in Addis Ababa was conducted using caregiver interviews and clinical chart review. Data were analyzed using SPSS V.26. Binary and multivariable logistic regression was used to identify factors related to the delayed diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Totally, 423 children with structural birth defects were enrolled; 358 (84.6%) were male. Median age at the time of data collection was 2.12 years (interquartile range (IQR), 0.8\u20135.0 years). Among 441 diagosed defects, the three most frequent structural birth defects were hypospadias (133, 30.2%), undescended testes (95, 21.5%), and anorectal malformation (38, 8.6%). Among 77 children with prenatally detectable defects, 32 were diagnosed antenatally. A total of 411 (97.2%) of the mothers had antenatal follow-up. Among 362 facility-born children with externally visible or clinically detectable defects, 104 (28.7%) were diagnosed before discharge. Overall, the diagnosis of a structural birth defect was delayed in 274 (64.8%) children. The main reasons for this delay were lack of awareness, delayed referral, and false reassurance by a health professional. Being delivered at a health center (\n                      <jats:italic>p<\/jats:italic>\n                      &lt;0.001, adjusted odds ratio (\n                      <jats:italic>aOR<\/jats:italic>\n                      )=2.17) was associated with a delayed diagnosis.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>There is a significant delay in diagnosing structural birth defects during both the antenatal and postnatal periods. These missed opportunities can be addressed through comprehensive screening programs, capacity-building sessions for healthcare workers, and raising public awareness.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/wjps-2026-001186","type":"journal-article","created":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T12:52:02Z","timestamp":1786539122000},"page":"e001186","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Timing of diagnosis and factors associated with delayed detection of structural birth defects in children: a multicenter cross-sectional study from Addis Ababa, Ethiopia"],"prefix":"10.1136","volume":"9","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8309-772X","authenticated-orcid":false,"given":"Hana Abebe","family":"Gebreselassie","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"239","published-online":{"date-parts":[[2026,8,12]]},"reference":[{"key":"2026081205500921000_9.4.e001186.1","unstructured":"World Health Organization . Birth defects surveillance: a manual for programme managers. 2014. Available: https:\/\/iris.who.int\/handle\/10665\/110223 [Accessed 16 Jan 2026]."},{"key":"2026081205500921000_9.4.e001186.2","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3109\/14767058.2012.664943","article-title":"Congenital malformations","volume":"25 Suppl 1","author":"Corsello","year":"2012","journal-title":"J Matern Fetal Neonatal Med"},{"key":"2026081205500921000_9.4.e001186.3","doi-asserted-by":"crossref","unstructured":"Dayyabu Aliyu L . Fetal congenital anomalies in africa: diagnostic and management challenges. In: Congenital anomalies in newborn infants - Clinical and etiopathological perspectives. IntechOpen, 2021. Available: https:\/\/doi.org\/10.5772\/intechopen.91994 [accessed 15 Jan 2026].","DOI":"10.5772\/intechopen.91994"},{"key":"2026081205500921000_9.4.e001186.4","unstructured":"World Health Organization . Congenital anomalies. 2023. Available: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/congenital-disorders"},{"key":"2026081205500921000_9.4.e001186.5","doi-asserted-by":"crossref","DOI":"10.1155\/2021\/2426891","article-title":"Congenital Anomalies and Associated Factors among Newborns in Bishoftu General Hospital, Oromia, Ethiopia: A Retrospective Study","volume":"2021","author":"Gedamu","year":"2021","journal-title":"J Environ Public Health"},{"key":"2026081205500921000_9.4.e001186.6","doi-asserted-by":"crossref","first-page":"29","DOI":"10.2147\/PHMT.S235591","article-title":"Prevalence and Factors Associated with Neonatal Mortality at Ayder Comprehensive Specialized Hospital, Northern Ethiopia. A Cross-Sectional Study","volume":"11","author":"Hadgu","year":"2020","journal-title":"Pediatric Health Med Ther"},{"key":"2026081205500921000_9.4.e001186.7","doi-asserted-by":"crossref","DOI":"10.1186\/s12884-017-1420-7","article-title":"Factors associated with perinatal mortality among public health deliveries in Addis Ababa, Ethiopia, an unmatched case control study","volume":"17","author":"Getiye","year":"2017","journal-title":"BMC Pregnancy Childbirth"},{"key":"2026081205500921000_9.4.e001186.8","unstructured":"Sub-saharan african network for congenital anomalies: surveillance, prevention and care. UK Research and Innovation; 2022. Available: https:\/\/gtr.ukri.org\/projects?ref=MR%2FT039132%2F1 [Accessed 14 Jan 2026]."},{"key":"2026081205500921000_9.4.e001186.9","doi-asserted-by":"crossref","first-page":"745","DOI":"10.5336\/medsci.2011-26349","article-title":"Delayed Referral of Congenital Anomalies","volume":"32","author":"\u00c7avu\u015fo\u011flu","year":"2012","journal-title":"Turkiye Klinikleri J Med Sci"},{"key":"2026081205500921000_9.4.e001186.10","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1007\/s10995-023-03591-x","article-title":"Prevalence, Pattern, and Outcome of Congenital Anomalies Admitted to a Neonatal Unit in a Low-Income Country-a Ten-Year Retrospective Study","volume":"27","author":"Anane-Fenin","year":"2023","journal-title":"Matern Child Health 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