{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T14:08:11Z","timestamp":1777039691161,"version":"3.51.4"},"reference-count":24,"publisher":"BMJ","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Clin Pathol"],"published-print":{"date-parts":[[1972,9]]},"abstract":"<jats:p>\n                    Serum levels of albumin, transferrin, \u03b1\n                    <jats:sub>2<\/jats:sub>\n                    -macroglobulin, \u03b2\n                    <jats:sub>1<\/jats:sub>\n                    C\/\u03b2\n                    <jats:sub>1<\/jats:sub>\n                    A, IgA, IgG, and IgM have been determined in 73 patients with primary biliary cirrhosis and in age- and sex-matched controls. A highly significant fall in albumin was demonstrated, and there were highly significant increases in \u03b1\n                    <jats:sub>2<\/jats:sub>\n                    -macroglobulin and all three immunoglobulin levels. Transferrin and \u03b2\n                    <jats:sub>1<\/jats:sub>\n                    \/C\u03b2\n                    <jats:sub>1<\/jats:sub>\n                    A levels were unchanged. No significant correlations were found between the titre of antimitochondrial antibody, the duration of symptoms, and any of the serum proteins estimated. A highly significant positive correlation was present between serum albumin and transferrin levels in both patient and control groups.\n                  <\/jats:p>","DOI":"10.1136\/jcp.25.9.789","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"789-792","source":"Crossref","is-referenced-by-count":20,"title":["Serum protein levels in primary biliary cirrhosis"],"prefix":"10.1136","volume":"25","author":[{"given":"R. N. M.","family":"MacSween","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. H. 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