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Nine compounds showed sufficient activity to merit further consideration, ie, acriflavine, proflavine, hydroxystilbamidine isethionate, paromomycin, miconazole, amphoterin, neomycin, polymyxin, and the last two combined in Neosporin.<\/jats:p>","DOI":"10.1136\/jcp.29.7.648","type":"journal-article","created":{"date-parts":[[2007,6,9]],"date-time":"2007-06-09T00:50:46Z","timestamp":1181350246000},"page":"648-651","source":"Crossref","is-referenced-by-count":44,"title":["Chemotherapeutic compounds and Acanthamoebae from eye infections."],"prefix":"10.1136","volume":"29","author":[{"given":"J","family":"Nagington","sequence":"first","affiliation":[]},{"given":"J E","family":"Richards","sequence":"additional","affiliation":[]}],"member":"239","published-online":{"date-parts":[[1976,7,1]]},"reference":[{"key":"ref_1","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1136\/bmj.1.5696.596","article-title":"Primary amoebic meningoencephalitis in Britain","volume":"1","author":"Apley, J.; Clarke, S.K.R.; Roome, A.P.C.H.; Sandry, S.A.; Saygi, G.; Silk, B.; Warhurst, D.C.","year":"1970","unstructured":"Apley, J., Clarke, S. K. R., Roome, A. P. C. H., Sandry, S. A., Saygi, G., Silk, B., and Warhurst, D. C. (1970). Primary amoebic meningoencephalitis in Britain. Brit. med. J., 1, 596-599.","journal-title":"Brit. med. J"},{"key":"ref_2","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1136\/jcp.22.4.470","article-title":"Sensitivity to amphotericin B. of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis","volume":"22","author":"Carter, R.F.","year":"1969","unstructured":"Carter, R. F. (1969). Sensitivity to amphotericin B. of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis. J. clin. Path., 22, 470-474.","journal-title":"J. clin. Path"},{"key":"ref_3","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/0035-9203(72)90147-2","article-title":"Primary amoebic meningoencephalitis","volume":"66","author":"Carter, R.F.","year":"1972","unstructured":"Carter, R. F. (1972). Primary amoebic meningoencephalitis. Trans. ro.y. Soc. trop. Med. Hyg., 66, 193-208.","journal-title":"Trans. ro.y. Soc. trop. Med. Hyg"},{"key":"ref_4","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1136\/jcp.23.8.649","article-title":"Sensitivity of Hartmannella (Acanthamoeba) to 5-fluorocytosine, hydroxystilbamidine, and other substances","volume":"23","author":"Casemore, D.P.","year":"1970","unstructured":"Casemore, D. P. (1970). Sensitivity of Hartmannella (Acanthamoeba) to 5-fluorocytosine, hydroxystilbamidine, and other substances. J. clin. Path., 23, 649-652.","journal-title":"J. clin. Path"},{"key":"ref_5","first-page":"357","article-title":"The effect of some drugs on the growth of the pathogenic strain of Hartmannella (Acanthamoeba) castellanii in vitro. Folia parasit","volume":"16","author":"Cerva, L.","year":"1969","unstructured":"Cerva, L. (1969). The effect of some drugs on the growth of the pathogenic strain of Hartmannella (Acanthamoeba) castellanii in vitro. Folia parasit. (Praha), 16, 357-360","journal-title":"(Praha)"},{"key":"ref_6","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1093\/ajcp\/43.4.361","article-title":"Hartmannella castellanii (Acanthamoeba sp.): preliminary report on experimental chemotherapy","volume":"43","author":"Culbertson, C.G.; Holmes, D.H.; Overton, W.M.","year":"1965","unstructured":"Culbertson, C. G., Holmes, D. H., and Overton, W. M. (1965). Hartmannella castellanii (Acanthamoeba sp.): preliminary report on experimental chemotherapy. Amer. J. clin. Path., 43, 361-364.","journal-title":"Amer. J. clin. Path"},{"key":"ref_7","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1136\/jcp.28.6.446","article-title":"Effect of clotrimazole on Naegleria Jowleri","volume":"28","author":"Jamieson, A.","year":"1975","unstructured":"Jamieson, A. (1975). Effect of clotrimazole on Naegleria Jowleri. J. clin. Path., 28, 446-449.","journal-title":"J. clin. Path"},{"key":"ref_8","article-title":"Unpublished communication read at Ocular Microbiology and Immunology Group","author":"Jones, D.B.","year":"1973","unstructured":"Jones, D. B. (1973). Unpublished communication read at Ocular Microbiology and Immunology Group in Dallas, Texas, U.S.A. October 1973."},{"key":"ref_9","first-page":"1537","article-title":"Amoebic infection of the eye","volume":"2","author":"Nagington, J.; Watson, P.G.; Playfair, T.J.; McGill, J.; Jones, B.R.; Steele, A.D.Mc G.","year":"1974","unstructured":"Nagington, J., Watson, P. G., Playfair, T. J., McGill, J., Jones, B. R., and Steele, A. D. Mc.G. (1974). Amoebic infection of the eye. Lancet, 2, 1537-1540.","journal-title":"Lancet"},{"key":"ref_10","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1136\/bmj.1.5480.130","article-title":"Ryan virus: a possible new human pathogen","volume":"1","author":"Pereira, M.S.; Marsden, H.B.; Corbitt, G.; Tobin, J.O.'H.","year":"1966","unstructured":"Pereira, M. S., Marsden, H. B., Corbitt, G., and Tobin, J. O'H. (1966). Ryan virus: a possible new human pathogen. Brit. med. J., 1, 130-132.","journal-title":"Brit. med. J"},{"key":"ref_11","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1099\/00221287-50-2-207","article-title":"Study of a small amoeba from mammalian cell cultures infected with 'Ryan virus'","volume":"50","author":"Warhurst, D.C.; Armstrong, J.A.","year":"1968","unstructured":"Warhurst, D. C., and Armstrong, J. A. (1968). Study of a small amoeba from mammalian cell cultures infected with 'Ryan virus'. 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