{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:51:58Z","timestamp":1762005118134,"version":"3.44.0"},"reference-count":10,"publisher":"BMJ","issue":"8","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,8,13]]},"published-print":{"date-parts":[[2019,8]]},"abstract":"<jats:p>A 62-year-old man was admitted to the emergency department due to fever and acute heart failure. A transthoracic echocardiogram revealed severe aortic valve obstruction. He was an hepatic transplant recipient and was medicated with everolimus. He underwent mitral and aortic valve replacement with prosthetic valves 4\u2009years ago. Due to his medical background, therapy and clinical presentation, empirical therapy for infective endocarditis was started. Transoesophageal echocardiogram showed severe aortic valve regurgitation but no other findings suggestive of endocarditis. Computed tomography (CT) revealed pulmonary infiltrates compatible with infection and no evidence of septic embolisation. Multiple sets of blood cultures were negative. <jats:italic>Proteus mirabilis<\/jats:italic> was isolated in bronchial lavage and antibiotic therapy was adjusted. The patient underwent aortic valve replacement, with no macroscopic findings suggestive of endocarditis. <jats:italic>P. mirabilis<\/jats:italic> was isolated in the surgically removed valve. Dual antibiotic therapy was successfully administered for 6\u2009weeks.<\/jats:p>","DOI":"10.1136\/bcr-2019-230575","type":"journal-article","created":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T07:35:35Z","timestamp":1567064135000},"page":"e230575","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":7,"title":["<i>Proteus mirabilis<\/i> endocarditis"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9401-526X","authenticated-orcid":false,"given":"In\u00eas","family":"Albuquerque","sequence":"first","affiliation":[{"name":"Internal Medicine, Centro Hospitalar de Sao Joao EPE, Porto, Portugal"}]},{"given":"Ana Rita","family":"Silva","sequence":"additional","affiliation":[{"name":"Internal Medicine, Unidade Hospitalar de Bragan\u00e7a, Braganca, Portugal"}]},{"given":"Marta Soares","family":"Carreira","sequence":"additional","affiliation":[{"name":"Internal Medicine, Centro Hospitalar de Sao Joao EPE, Porto, Portugal"}]},{"given":"Fernando","family":"Fri\u00f5es","sequence":"additional","affiliation":[{"name":"Internal Medicine, Centro Hospitalar S\u00e3o Jo\u00e3o, Oporto, Portugal"}]}],"member":"239","published-online":{"date-parts":[[2019,8,28]]},"reference":[{"key":"2025082711062523000_12.8.e230575.1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-2048"},{"key":"2025082711062523000_12.8.e230575.2","doi-asserted-by":"crossref","unstructured":"Ambrosioni J , Hernandez-Meneses M , T\u00e9llez A , et al . 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Native valve Proteus mirabilis endocarditis: successful treatment of a rare entity formulated by in vitro synergy antibiotic testing. BMJ Case Rep 2016:bcr2016215956.doi:10.1136\/bcr-2016-215956","DOI":"10.1136\/bcr-2016-215956"},{"key":"2025082711062523000_12.8.e230575.7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2010.12.002"},{"key":"2025082711062523000_12.8.e230575.8","doi-asserted-by":"publisher","DOI":"10.1093\/ejcts\/ezw126"},{"key":"2025082711062523000_12.8.e230575.9","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1016\/j.ijge.2014.09.003","article-title":"An unusual cause of infective endocarditis: Proteus mirabilis\u00a0bacteremia from an infected pressure ulcer","volume":"9","author":"Liu","year":"2015","journal-title":"International Journal of Gerontology"},{"key":"2025082711062523000_12.8.e230575.10","doi-asserted-by":"crossref","unstructured":"Habib G . ESC Guidelines for the management of infective endocarditis. European Heart Journal 2015.","DOI":"10.1007\/978-3-319-32432-6_22"}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-230575","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T18:06:34Z","timestamp":1756317994000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-230575"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,8]]},"references-count":10,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2019,8,28]]},"published-print":{"date-parts":[[2019,8]]}},"alternative-id":["10.1136\/bcr-2019-230575"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-230575","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,8]]}}}