{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T16:40:08Z","timestamp":1756312808057,"version":"3.44.0"},"reference-count":26,"publisher":"BMJ","issue":"9","funder":[{"DOI":"10.13039\/501100001871","name":"Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001871","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2019,8,19]]},"published-print":{"date-parts":[[2019,9]]},"abstract":"<jats:p>Primary retroperitoneal mucinous cystic neoplasms (PRMCN) with borderline malignancy are exceptionally rare tumours with lack of pathognomonic clinical and imaging-specific features. Here, we report a case of PRMCN with borderline malignancy in a 62-year-old woman who presented with abdominal pain. Imaging studies revealed a well-defined cystic mass on the right flank in close relation with the cecum and caecal appendix, without other findings suggestive of malignancy. A possible diagnosis of an ovarian epithelial tumour was ruled out intraoperatively. After surgical excision, microscopic examination allowed the final diagnosis. As there is no evidence of disease during follow-up, complete tumour resection without cystic rupture appears to be the best therapeutic option. Thus, although rare, this tumour should be considered when imaging findings suggest an ovarian mucinous neoplasm in women with normal ovaries. An international registry for rare tumours and longer follow-ups may contribute for more consistent approach for managing these patients.<\/jats:p>","DOI":"10.1136\/bcr-2019-230708","type":"journal-article","created":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T08:07:00Z","timestamp":1567670820000},"page":"e230708","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":3,"title":["A rare case of a primary retroperitoneal mucinous cystic tumour with borderline malignancy and literature review"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4842-1299","authenticated-orcid":false,"given":"Mariana M","family":"Chaves","sequence":"first","affiliation":[{"name":"Radiology, Hospital do Divino Espirito Santo de Ponta Delgada EPE, Ponta Delgada, Azores, Portugal"}]},{"given":"Rita","family":"Castro","sequence":"additional","affiliation":[{"name":"General Surgery, Hospital do Divino Espirito Santo de Ponta Delgada EPE, Ponta Delgada, Azores, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1451-6705","authenticated-orcid":false,"given":"Luisa","family":"Mota-Vieira","sequence":"additional","affiliation":[{"name":"Molecular Genetics and Pathology, Hospital do Divino Espirito Santo de Ponta Delgada EPE, Ponta Delgada, Azores, Portugal"},{"name":"BioISI \u2013 Biosystems & Integrative Sciences Institute, Universidade de Lisboa Faculdade de Ciencias, Lisboa, Lisboa, Portugal"}]},{"given":"V\u00edtor","family":"Carneiro","sequence":"additional","affiliation":[{"name":"Pathology, Hospital do Divino Espirito Santo de Ponta Delgada EPE, Ponta Delgada, Azores, Portugal"}]}],"member":"239","published-online":{"date-parts":[[2019,9,4]]},"reference":[{"key":"2025082708585483000_12.9.e230708.1","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1186\/1477-7819-9-98","article-title":"Primary retroperitoneal mucinous cystadenoma of borderline malignancy in a male patient. Case report and review of the literature","volume":"9","author":"Falidas","year":"2011","journal-title":"World J Surg Oncol"},{"key":"2025082708585483000_12.9.e230708.2","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001013"},{"key":"2025082708585483000_12.9.e230708.3","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1097\/COC.0000000000000298","article-title":"Primary Retroperitoneal Mucinous Cystic Neoplasm: Authors' Experience and Review of the Literature","volume":"39","author":"Dayan","year":"2016","journal-title":"Am J Clin Oncol"},{"key":"2025082708585483000_12.9.e230708.4","doi-asserted-by":"crossref","first-page":"722","DOI":"10.4081\/cp.2015.722","article-title":"Primary retroperitoneal mucinous cystic tumors with borderline malignancy: a case report and literature review","volume":"5","author":"Manrai","year":"2015","journal-title":"Clin Pract"},{"key":"2025082708585483000_12.9.e230708.5","doi-asserted-by":"crossref","unstructured":"Lee SE , Hc O , Park YG , et al . Laparoscopic excision of primary retroperitoneal mucinous cystadenoma and malignant predicting factors derived from literature review. Int J Surg Case Rep 2015:9:130\u20133.","DOI":"10.1016\/j.ijscr.2015.02.050"},{"key":"2025082708585483000_12.9.e230708.6","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.2217\/fon-2017-0649","article-title":"A case report and a literature review of primary retroperitoneal mucinous cystadenoma: the importance of imaging in diagnosis and management","volume":"14","author":"Pesapane","year":"2018","journal-title":"Future Oncol"},{"issue":"suppl_1","key":"2025082708585483000_12.9.e230708.7","doi-asserted-by":"crossref","first-page":"S85","DOI":"10.1148\/radiographics.19.suppl_1.g99oc10s85","article-title":"CT of epithelial ovarian tumors","volume":"19","author":"Kawamoto","year":"1999","journal-title":"Radiographics"},{"key":"2025082708585483000_12.9.e230708.8","first-page":"489","article-title":"[A case of retroperitoneal mucinous cystadenoma of borderline malignancy]","volume":"88","author":"Nagata","year":"1987","journal-title":"Nihon Geka Gakkai Zasshi"},{"key":"2025082708585483000_12.9.e230708.9","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1111\/j.1365-2559.1988.tb01972.x","article-title":"Cystic mucinous tumours of the mesentery and retroperitoneum: report of three cases","volume":"12","author":"Banerjee","year":"1988","journal-title":"Histopathology"},{"key":"2025082708585483000_12.9.e230708.10","first-page":"261","article-title":"Mucinous cystic tumor of the retroperitoneum. A report of two cases","volume":"38","author":"Motoyama","year":"1994","journal-title":"Acta Cytol"},{"key":"2025082708585483000_12.9.e230708.11","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1006\/gyno.1996.0115","article-title":"Primary retroperitoneal mucinous cystadenocarcinoma of low malignant potential: a case report and literature review","volume":"61","author":"Pearl","year":"1996","journal-title":"Gynecol Oncol"},{"key":"2025082708585483000_12.9.e230708.12","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1699-0463.1997.tb00597.x","article-title":"Primary retroperitoneal mucinous tumor of low malignant potential: histogenetic aspects and review of the literature","volume":"105","author":"Papadogiannakis","year":"1997","journal-title":"APMIS"},{"key":"2025082708585483000_12.9.e230708.13","doi-asserted-by":"publisher","DOI":"10.1007\/s005950050137"},{"key":"2025082708585483000_12.9.e230708.14","doi-asserted-by":"crossref","first-page":"691","DOI":"10.1055\/s-2003-41380","article-title":"Primary retroperitoneal mucinous cystadenoma. A case report and brief review of the literature","volume":"128","author":"Gutsu","year":"2003","journal-title":"Zentralbl Chir"},{"key":"2025082708585483000_12.9.e230708.15","first-page":"204","article-title":"Primary mucinous cystic neoplasm of the retroperitoneum: a report of three cases","volume":"37","author":"Song","year":"2003","journal-title":"Korean J Pathol"},{"key":"2025082708585483000_12.9.e230708.16","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1097\/01.pgp.0000161313.30054.1d","article-title":"Primary retroperitoneal mucinous cystadenoma of borderline malignancy: a case report and review of the literature","volume":"24","author":"Matsubara","year":"2005","journal-title":"Int J Gynecol Pathol"},{"key":"2025082708585483000_12.9.e230708.17","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s00428-007-0479-3","article-title":"Primary retroperitoneal mucinous cystadenoma with sarcoma like mural nodule. A case report and review of the literature","volume":"451","author":"Bakker","year":"2007","journal-title":"Virchows Arch"},{"key":"2025082708585483000_12.9.e230708.18","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1016\/j.ygyno.2007.04.023","article-title":"Primary retroperitoneal mucinous borderline tumor: a case report","volume":"106","author":"Cottrill","year":"2007","journal-title":"Gynecol Oncol"},{"key":"2025082708585483000_12.9.e230708.19","first-page":"2309","article-title":"Huge primary retroperitoneal mucinous cystadenoma of borderline malignancy mimicking an ovarian mass: case report and review","volume":"28","author":"Bifulco","year":"2008","journal-title":"Anticancer Res"},{"key":"2025082708585483000_12.9.e230708.20","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181909018"},{"key":"2025082708585483000_12.9.e230708.21","doi-asserted-by":"crossref","first-page":"9098","DOI":"10.1186\/1757-1626-2-9098","article-title":"Primary retroperitoneal mucinous cystadenoma with borderline malignancy in a male patient: a case report","volume":"2","author":"Benkirane","year":"2009","journal-title":"Cases J"},{"key":"2025082708585483000_12.9.e230708.22","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.urology.2013.03.031","article-title":"Male primary retroperitoneal mucinous cystadenoma","volume":"82","author":"Mattei","year":"2013","journal-title":"Urology"},{"key":"2025082708585483000_12.9.e230708.23","first-page":"717","article-title":"Primary retroperitoneal mucinous tumor of low malignant potential in a Persian woman","volume":"52","author":"Haeri","year":"2014","journal-title":"Acta Med Iran"},{"key":"2025082708585483000_12.9.e230708.24","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1097\/PAT.0000000000000261","article-title":"A rare case of primary retroperitoneal mucinous neoplasm in a male patient","volume":"47","author":"Vargas","year":"2015","journal-title":"Pathology"},{"key":"2025082708585483000_12.9.e230708.25","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1007\/s00404-015-3975-8","article-title":"Primary retroperitoneal mucinous cystadenocarcinoma (PRMCa): a systematic review of the literature and meta-analysis","volume":"293","author":"Myriokefalitaki","year":"2016","journal-title":"Arch Gynecol Obstet"},{"key":"2025082708585483000_12.9.e230708.26","unstructured":"Tavassoli FA , Devillee P . Chapiter 2. Tumours of the ovary and peritoneum. World Health Organization Classification of Tumours: Pathology and Genetics Tumours of the Breast and Female Genital Organs: World Health Organization, 2003."}],"container-title":["BMJ Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/syndication.highwire.org\/content\/doi\/10.1136\/bcr-2019-230708","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,27]],"date-time":"2025-08-27T15:59:06Z","timestamp":1756310346000},"score":1,"resource":{"primary":{"URL":"https:\/\/casereports.bmj.com\/lookup\/doi\/10.1136\/bcr-2019-230708"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":26,"journal-issue":{"issue":"9","published-online":{"date-parts":[[2019,9,4]]},"published-print":{"date-parts":[[2019,9]]}},"alternative-id":["10.1136\/bcr-2019-230708"],"URL":"https:\/\/doi.org\/10.1136\/bcr-2019-230708","relation":{},"ISSN":["1757-790X"],"issn-type":[{"type":"electronic","value":"1757-790X"}],"subject":[],"published":{"date-parts":[[2019,9]]}}}