{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,28]],"date-time":"2025-08-28T00:06:19Z","timestamp":1756339579096,"version":"3.44.0"},"reference-count":11,"publisher":"BMJ","issue":"7","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Case Rep"],"accepted":{"date-parts":[[2021,6,20]]},"published-print":{"date-parts":[[2021,7]]},"abstract":"<jats:p>The most frequent type of thyroid malignancy in children is papillary thyroid carcinoma (PTC), which usually presents as a thyroid nodule, but may also present as a diffuse infiltration with microcalcifications. Herein, we report the case of an uncommon presentation of a PTC in a 7-year-old boy. The child was referred for a goiter with cervical lymphadenopathies. Ultrasonography showed a hypervascularised goiter without microcalcifications but with numerous bilateral cervical nodular formations. A lymph node biopsy revealed metastatic thyroid cancer, hence a total thyroidectomy and complete neck dissection were performed. Histopathology confirmed a PTC. Ablative <jats:sup>131<\/jats:sup>I, 30 mCi was performed 4 months postsurgery. At the end of this treatment, a metastatic lung nodule was identified. Since then, another three ablative <jats:sup>131<\/jats:sup>I treatments have been administered. Thyroid cancers presenting as a diffuse infiltration without microcalcifications are rare. In the presence of lymphadenopathies, thyroid cancer needs to be suspected, even without microcalcifications.<\/jats:p>","DOI":"10.1136\/bcr-2021-242278","type":"journal-article","created":{"date-parts":[[2021,7,15]],"date-time":"2021-07-15T12:35:44Z","timestamp":1626352544000},"page":"e242278","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":0,"title":["Papillary thyroid carcinoma in a 7-year-old boy presenting with a goitre without microcalcifications and enlarged cervical lymph nodes"],"prefix":"10.1136","volume":"14","author":[{"given":"Maria Cecilia","family":"Schultze","sequence":"first","affiliation":[{"name":"Pediatrics, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg"}]},{"given":"Cintia","family":"Castro-Correia","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology and Diabetology Unit, Centro Hospitalar Universitario de Sao Joao, Porto, Portugal"}]},{"given":"Maria","family":"Bom-Sucesso","sequence":"additional","affiliation":[{"name":"Pediatric Hematology-Oncology Unit, Hospital de Sao Joao, Porto, Portugal"}]},{"given":"Marianne","family":"Becker","sequence":"additional","affiliation":[{"name":"Pediatric Endocrinology and Diabetology, Centre Hospitalier de Luxembourg, Luxembourg, Luxembourg"}]}],"member":"239","published-online":{"date-parts":[[2021,7,15]]},"reference":[{"key":"2025082711274048000_14.7.e242278.1","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2014.0460"},{"key":"2025082711274048000_14.7.e242278.2","unstructured":"Howlader N , Noone AM , Krapcho M . 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