{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,15]],"date-time":"2025-12-15T20:03:35Z","timestamp":1765829015716,"version":"3.48.0"},"reference-count":36,"publisher":"BMJ","issue":"2","content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2014,1,24]]},"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Multimorbidity is defined as the co-occurrence of more than one chronic disease in one person without assigning an index disease. This rapidly increasing phenomenon markedly influences patients\u2019 overall health, has major implications for effective provision of healthcare services and has a significant economic toll on individuals and society. Since Portugal is a country with a growing ageing population, a better understanding of the role of multimorbidity should be assessed. The aim of this study is to further the knowledge of the epidemiological factors associated with multimorbidity in Portugal, chiefly its prevalence and the health and social implications.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>This study protocol describes a primary care nationwide three-phase study. The first phase is drawn to access the prevalence and patterns of multimorbidity. In the second phase, individual parameters are assessed, such as patients\u2019 health-related quality of life, perceived family support and unmet health needs of patients with multimorbidity. The third and last phase of this study aims to characterise general practitioners\u2019 knowledge, awareness and practices related to multimorbidity management.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>The study will be conducted in accordance with the principles expressed in the Declaration of Helsinki. It has full approval from the Ethics Committee of the Faculty of Health Sciences, University of Beira Interior, and the Ethics Committee of the Central Health Region of Portugal. Study results will be published in peer-reviewed journals and presented at national and international conferences.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2013-004113","type":"journal-article","created":{"date-parts":[[2014,2,15]],"date-time":"2014-02-15T00:20:11Z","timestamp":1392423611000},"page":"e004113","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":5,"title":["Multimorbidity in primary care in Portugal (MM-PT): a cross-sectional three-phase observational study protocol"],"prefix":"10.1136","volume":"4","author":[{"given":"Filipe","family":"Prazeres","sequence":"first","affiliation":[{"name":"Faculdade de Ci\u00eancias da Sa\u00fade, Universidade da Beira Interior, Covilh\u00e3, Portugal"},{"name":"Centro de Sa\u00fade de Aveiro, Aveiro, Portugal"}]},{"given":"Luiz","family":"Santiago","sequence":"additional","affiliation":[{"name":"Faculdade de Ci\u00eancias da Sa\u00fade, Universidade da Beira Interior, Covilh\u00e3, Portugal"},{"name":"USF Top\u00e1zio, Coimbra, Portugal"}]}],"member":"239","published-online":{"date-parts":[[2014,2,14]]},"reference":[{"key":"2025121511572632000_4.2.e004113.1","doi-asserted-by":"publisher","DOI":"10.3109\/13814789609162146"},{"key":"2025121511572632000_4.2.e004113.2","doi-asserted-by":"publisher","DOI":"10.1016\/S0895-4356(00)00358-9"},{"key":"2025121511572632000_4.2.e004113.3","doi-asserted-by":"publisher","DOI":"10.1370\/afm.272"},{"key":"2025121511572632000_4.2.e004113.4","doi-asserted-by":"publisher","DOI":"10.1370\/afm.1337"},{"key":"2025121511572632000_4.2.e004113.5","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmt012"},{"key":"2025121511572632000_4.2.e004113.6","unstructured":"Europe W . 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