{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T07:21:20Z","timestamp":1765610480155,"version":"3.48.0"},"reference-count":22,"publisher":"BMJ","issue":"5","license":[{"start":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T00:00:00Z","timestamp":1651622400000},"content-version":"unspecified","delay-in-days":3,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"FCT\u2014Funda\u00e7\u00e3o para a Ci\u00eancia e a Tecnologia","award":["UIDB\/4255\/2020"],"award-info":[{"award-number":["UIDB\/4255\/2020"]}]}],"content-domain":{"domain":["bmj.com"],"crossmark-restriction":true},"short-container-title":["BMJ Open"],"accepted":{"date-parts":[[2022,3,17]]},"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>In the last decades, the number of older people living with chronic diseases has rapidly increased. The prevalence of palliative care needs in this population can reach 17%, making the general practitioner a cornerstone in the identification and first medical intervention delivery. Therefore, knowing the primary care interventions that effectively improve the quality of life of these patients can play an important role in the delivery of healthcare.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods and analysis<\/jats:title>\n                    <jats:p>We will systematically review randomised controlled trials evaluating the effect of non-pharmacologic primary care interventions on the quality of life of older patients (\u226565 years) with palliative care needs. PsycINFO, EMBASE, MEDLINE, Cochrane and CINAHL will be searched until December 2021. Screening, data extraction and quality evaluation (using the Cochrane RoB 2.0 tool) will be done by independently by two reviewers, with disagreements solved by a third reviewer. We will conduct meta-analysis if appropriate. In case of high heterogeneity, findings will be analysed by subgroup according to intervention type, main disease\/symptoms and care context. Evidence will be graded using the Grading of Recommendations Assessment, Development and Evaluation approach. We will perform a sensitivity analysis based on study quality. Publication bias will be assessed using funnel plots.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Ethics and dissemination<\/jats:title>\n                    <jats:p>Formal ethical approval is not required as primary data will not be collected. The results will be disseminated through a peer-reviewed publication, conference presentation and the press.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>PROSPERO registration number<\/jats:title>\n                    <jats:p>CRD42020154216.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1136\/bmjopen-2021-060517","type":"journal-article","created":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T12:31:51Z","timestamp":1651667511000},"page":"e060517","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":4,"title":["Non-pharmacological interventions in primary care to improve the quality of life of older patients with palliative care needs: a systematic review protocol"],"prefix":"10.1136","volume":"12","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9214-6995","authenticated-orcid":false,"given":"Carlos","family":"Sei\u00e7a Cardoso","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Coimbra, Portugal"},{"name":"CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4586-2910","authenticated-orcid":false,"given":"Matilde","family":"Monteiro-Soares","sequence":"additional","affiliation":[{"name":"CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal"},{"name":"MEDCIDS - Departamento de Ci\u00eancias da Informa\u00e7\u00e3o e da Decis\u00e3o em Sa\u00fade, Universidade do Porto, Porto, Portugal"},{"name":"Escola Superior de Sa\u00fade da Cruz Vermelha Portuguesa, Cruz Vermelha Portuguesa, Lisbon, Portugal"}]},{"given":"Joana","family":"Rita Matos","sequence":"additional","affiliation":[{"name":"Family Health Unit Fernando Namora, Centre Regional Health Administration, Coimbra, Portugal"}]},{"given":"Filipe","family":"Prazeres","sequence":"additional","affiliation":[{"name":"CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal"},{"name":"Faculty of Health Sciences, Universidade of Beira Interior, Covilh\u00e3, Portugal"},{"name":"Family Health Unit Beira Ria, Centre Regional Health Administration, Aveiro, Portugal"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8561-5167","authenticated-orcid":false,"given":"Carlos","family":"Martins","sequence":"additional","affiliation":[{"name":"CINTESIS - Center for Health Technology and Services Research, Faculty of Medicine, University of Porto, Porto, Portugal"},{"name":"MEDCIDS - Departamento de Ci\u00eancias da Informa\u00e7\u00e3o e da Decis\u00e3o em Sa\u00fade, Universidade do Porto, Porto, Portugal"}]},{"given":"Barbara","family":"Gomes","sequence":"additional","affiliation":[{"name":"Faculty of Medicine, University of Coimbra, Coimbra, Coimbra, Portugal"},{"name":"Cicely Saunders Institute of Palliative Care, Policy and Rehabilitation, King's College London, London, London, UK"}]}],"member":"239","published-online":{"date-parts":[[2022,5,4]]},"reference":[{"key":"2025121223155614000_12.5.e060517.1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61347-7"},{"key":"2025121223155614000_12.5.e060517.2","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1089\/jpm.2017.0491","article-title":"Identified palliative care approach needs with SPICT in family practice: a preliminary observational study","volume":"21","author":"Hamano","year":"2018","journal-title":"J Palliat Med"},{"key":"2025121223155614000_12.5.e060517.3","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1016\/j.jpainsymman.2018.11.006","article-title":"Prevalence and characteristics of patients being at risk of deteriorating and dying in primary care","volume":"57","author":"Hamano","year":"2019","journal-title":"J Pain Symptom Manage"},{"key":"2025121223155614000_12.5.e060517.4","unstructured":"World Health Organization Geneva . 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