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A population attributable fraction (PAF) approach was used for most risk factors.<\/jats:p><\/jats:sec><jats:sec><jats:title>Results<\/jats:title><jats:p>In 2016, globally, an estimated 1.53 (95% uncertainty interval 1.39\u20131.68)\u2009million deaths and 76.1 (66.3\u201386.3)\u2009million DALYs were attributable to the included occupational risk factors, accounting for 2.8% of deaths and 3.2% of DALYs from all causes. Most deaths were attributable to PMGF, carcinogens (particularly asbestos), injury risk factors and SHS. Most DALYs were attributable to injury risk factors and ergonomic exposures. Men and persons 55 years or older were most affected. PAFs ranged from 26.8% for low back pain from ergonomic risk factors and 19.6% for hearing loss from noise to 3.4% for carcinogens. DALYs per capita were highest in Oceania, Southeast Asia and Central sub-Saharan Africa. On a per capita basis, between 1990 and 2016 there was an overall decrease of about 31% in deaths and 25% in DALYs.<\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusions<\/jats:title><jats:p>Occupational exposures continue to cause an important health burden worldwide, justifying the need for ongoing prevention and control initiatives.<\/jats:p><\/jats:sec>","DOI":"10.1136\/oemed-2019-106008","type":"journal-article","created":{"date-parts":[[2020,2,13]],"date-time":"2020-02-13T14:25:16Z","timestamp":1581603916000},"page":"133-141","update-policy":"https:\/\/doi.org\/10.1136\/crossmarkpolicy","source":"Crossref","is-referenced-by-count":89,"title":["Global and regional burden of disease and injury in 2016 arising from occupational exposures: a systematic analysis for the Global Burden of Disease Study 2016"],"prefix":"10.1136","volume":"77","author":[{"name":"GBD 2016 Occupational Risk Factors Collaborators","sequence":"first","affiliation":[]}],"member":"239","published-online":{"date-parts":[[2020,2,13]]},"reference":[{"key":"2020050723155229000_77.3.133.1","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1007\/s40572-017-0151-2","article-title":"The global burden of occupational disease","volume":"4","author":"Rushton","year":"2017","journal-title":"Curr Envir Health Rpt"},{"key":"2020050723155229000_77.3.133.2","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199909000-00032"},{"key":"2020050723155229000_77.3.133.3","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20211"},{"key":"2020050723155229000_77.3.133.4","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2014-102534"},{"key":"2020050723155229000_77.3.133.5","doi-asserted-by":"publisher","DOI":"10.1080\/15459624.2013.863131"},{"key":"2020050723155229000_77.3.133.6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(96)07495-8"},{"key":"2020050723155229000_77.3.133.7","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)61766-8"},{"key":"2020050723155229000_77.3.133.8","first-page":"1659","article-title":"Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks, 1990-2015: a systematic analysis for the global burden of disease study 2015","volume":"388","year":"2015","journal-title":"Lancet"},{"key":"2020050723155229000_77.3.133.9","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31679-8"},{"key":"2020050723155229000_77.3.133.10"},{"key":"2020050723155229000_77.3.133.11","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32225-6"},{"key":"2020050723155229000_77.3.133.12","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2019-106013"},{"key":"2020050723155229000_77.3.133.13","doi-asserted-by":"publisher","DOI":"10.1136\/oemed-2019-106012"},{"key":"2020050723155229000_77.3.133.14","first-page":"531","article-title":"The occurrence of lung cancer in man","volume":"9","author":"Levin","year":"1959","journal-title":"Acta Unio Internationalis Contra Cancrum"},{"key":"2020050723155229000_77.3.133.15","doi-asserted-by":"publisher","DOI":"10.1097\/01.ede.0000229155.05644.43"},{"key":"2020050723155229000_77.3.133.16","unstructured":"International Labour Office . 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