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Comput."],"published-print":{"date-parts":[[2025,2,28]]},"abstract":"<jats:p>Abstract.<\/jats:p>\n                  <jats:p>We introduce a data-driven and physics-informed framework for propagating uncertainty in stiff, multiscale random ordinary differential equations (RODEs) driven by correlated (colored) noise. Unlike systems subjected to Gaussian white noise, a deterministic equation for the joint probability density function (PDF) of RODE state variables does not exist in closed form. Moreover, such an equation would require as many phase-space variables as there are states in the RODE system. To alleviate this curse of dimensionality, we instead derive exact, albeit unclosed, reduced-order PDF (RoPDF) equations for low-dimensional observables\/quantities of interest. The unclosed terms take the form of state-dependent conditional expectations, which are directly estimated from data at sparse observation times. However, for systems exhibiting stiff, multiscale dynamics, data sparsity introduces regression discrepancies that compound during RoPDF evolution. This is overcome by introducing a kinetic-like defect term to the RoPDF equation, which is learned by assimilating in sparse, low-fidelity RoPDF estimates. Two assimilation methods are considered, namely nudging and deep neural networks, which are successfully tested against Monte Carlo simulations.<\/jats:p>","DOI":"10.1137\/23m1625366","type":"journal-article","created":{"date-parts":[[2025,1,15]],"date-time":"2025-01-15T04:01:08Z","timestamp":1736913668000},"page":"C52-C76","source":"Crossref","is-referenced-by-count":0,"title":["Data-Driven Closures and Assimilation for Stiff Multiscale Random Dynamics"],"prefix":"10.1137","volume":"47","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-4385-1912","authenticated-orcid":true,"given":"Tyler E.","family":"Maltba","sequence":"first","affiliation":[{"name":"Theoretical Division, Los Alamos National Laboratory, Los Alamos, NM 87545 USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6729-534X","authenticated-orcid":true,"given":"Hongli","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Statistics, University of Chicago, Chicago, IL 60637 USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D. Adrian","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Mathematics and Computer Science Division, Argonne National Laboratory, Lemont, IL 60439 USA."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"351","published-online":{"date-parts":[[2025,1,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1145\/360767.360779"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1029\/2018WR023383"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1080\/03610918.2014.957839"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/2016WR018745"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1137\/19M1260773"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1214\/10-AOS799"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4310\/CMS.2015.v13.n3.a1"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/0022-247X(78)90182-8"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/oso\/9780198523963.001.0001"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcp.2018.06.038"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-2789(02)00446-3"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1109\/TCS.1987.1086092"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1090\/gsm\/019"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1615\/.2020034232"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1287\/opre.1070.0496"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-6265-0_2"},{"key":"ref17","unstructured":"M. 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