{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T00:42:26Z","timestamp":1784853746425,"version":"3.55.0"},"reference-count":49,"publisher":"Canadian Science Publishing","issue":"11","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":["cdnsciencepub.com"],"crossmark-restriction":false},"short-container-title":["Appl. Physiol. Nutr. Metab."],"published-print":{"date-parts":[[2015,11]]},"abstract":"<jats:p> In a randomized cross-over study of 15 healthy men aged 20\u201330 years, we compared physiological and perceptual responses during treadmill and cycle exercise test protocols matched for increments in work rate \u2014 the source of increased locomotor muscle metabolic and contractile demands. The rates of O<jats:sub>2<\/jats:sub> consumption and CO<jats:sub>2<\/jats:sub> production were higher at the peak of treadmill versus cycle testing (p \u2264 0.05). Nevertheless, work rate, minute ventilation, tidal volume (V<jats:sub>T<\/jats:sub>), breathing frequency (f<jats:sub>R<\/jats:sub>), inspiratory capacity (IC), inspiratory reserve volume (IRV), tidal esophageal (Pes,tidal) and transdiaphragmatic pressure swings (Pdi,tidal), peak expiratory gastric pressures (Pga,peak), the root mean square of the diaphragm electromyogram (EMGdi,rms) expressed as a percentage of maximum EMGdi,rms (EMGdi,rms%max), and dyspnea ratings were similar at the peak of treadmill versus cycle testing (p &gt; 0.05). Ratings of leg discomfort were higher at the peak of cycle versus treadmill exercise (p \u2264 0.05), even though peak O<jats:sub>2<\/jats:sub> consumption was lower during cycling. Oxygen consumption, CO<jats:sub>2<\/jats:sub> production, minute ventilation, f<jats:sub>R<\/jats:sub>, Pes,tidal, Pdi,tidal and Pga,peak were higher (p \u2264 0.05), while V<jats:sub>T<\/jats:sub>, IC, IRV, EMGdi,rms%max, and ratings of dyspnea and leg discomfort were similar (p &gt; 0.05) at all or most submaximal work rates during treadmill versus cycle exercise. Our findings highlight important differences (and similarities) in physiological and perceptual responses at maximal and submaximal work rates during incremental treadmill and cycle exercise testing protocols. The lack of effect of exercise test modality on peak work rate advocates for the use of this readily available parameter to optimize training intensity determination, regardless of exercise training mode. <\/jats:p>","DOI":"10.1139\/apnm-2015-0179","type":"journal-article","created":{"date-parts":[[2015,8,4]],"date-time":"2015-08-04T21:37:38Z","timestamp":1438724258000},"page":"1199-1209","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":36,"title":["Physiological and perceptual responses to incremental exercise testing in healthy men: effect of exercise test modality"],"prefix":"10.1139","volume":"40","author":[{"given":"Kristina M.","family":"Muscat","sequence":"first","affiliation":[{"name":"Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Houssam G.","family":"Kotrach","sequence":"additional","affiliation":[{"name":"Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Courtney A.","family":"Wilkinson-Maitland","sequence":"additional","affiliation":[{"name":"Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele R.","family":"Schaeffer","sequence":"additional","affiliation":[{"name":"Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cassandra T.","family":"Mendonca","sequence":"additional","affiliation":[{"name":"Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis","family":"Jensen","sequence":"additional","affiliation":[{"name":"Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."},{"name":"Respiratory Epidemiology and Clinical Research Unit, Montr\u00e9al Chest Institute, McGill University Health Centre, Montr\u00e9al, QC H4A 3J1, Canada."},{"name":"Research Centre for Physical Activity and Health, McGill University, Montr\u00e9al, QC H2W 1S4, Canada."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"refg1\/ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0026-0495(03)00068-4"},{"key":"refg2\/ref2","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.167.2.211"},{"issue":"6","key":"refg3\/ref3","doi-asserted-by":"crossref","first-page":"2020","DOI":"10.1152\/jappl.1986.60.6.2020","volume":"60","author":"Beaver W.L.","year":"1986","journal-title":"J. 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