{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T20:01:05Z","timestamp":1791921665957,"version":"4.3.4"},"reference-count":43,"publisher":"Canadian Science Publishing","issue":"5","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":["cdnsciencepub.com"],"crossmark-restriction":false},"short-container-title":["Appl. Physiol. Nutr. Metab."],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p> Combative sport is one of the most physically intense forms of exercise, yet the effect of recovery interventions has been largely unexplored. We investigated the effect of cold-water immersion on structural, inflammatory, and physiological stress biomarkers following a mixed martial arts (MMA) contest preparation training session in comparison with passive recovery. Semiprofessional MMA competitors (n = 15) were randomly assigned to a cold-water immersion (15 min at 10 \u00b0C) or passive recovery protocol (ambient air) completed immediately following a contest preparation training session. Markers of muscle damage (urinary myoglobin), inflammation\/oxidative stress (urinary neopterin + total neopterin (neopterin + 7,8-dihydroneopterin)), and hypothalamic\u2013pituitary axis (HPA) activation (saliva cortisol) were determined before, immediately after, and 1, 2, and 24 h postsession. Ratings of perceived soreness and fatigue, counter movement jump, and gastrointestinal temperature were also measured. Concentrations of all biomarkers increased significantly (p &lt; 0.05) postsession. Cold water immersion attenuated increases in urinary neopterin (p &lt; 0.05, d = 0.58), total neopterin (p &lt; 0.05, d = 0.89), and saliva cortisol after 2 h (p &lt; 0.05, d = 0.68) and urinary neopterin again at 24 h (p &lt; 0.01, d = 0.57) in comparison with passive recovery. Perceived soreness, fatigue, and gastrointestinal temperatures were also lower for the cold-water immersion group at several time points postsession whilst counter movement jump did not differ. Combative sport athletes who are subjected to impact-induced stress may benefit from immediate cold-water immersion as a simple recovery intervention that reduces delayed onset muscle soreness as well as macrophage and HPA activation whilst not impairing functional performance. <\/jats:p>","DOI":"10.1139\/apnm-2016-0582","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T22:36:56Z","timestamp":1484692616000},"page":"529-536","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":60,"title":["The physiological response to cold-water immersion following a mixed martial arts training session"],"prefix":"10.1139","volume":"42","author":[{"given":"Angus","family":"Lindsay","sequence":"first","affiliation":[{"name":"Program in Physical Therapy, Department of Rehabilitation Medicine, University of Minnesota, Minneapolis, MN, USA."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Carr","sequence":"additional","affiliation":[{"name":"Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sean","family":"Cross","sequence":"additional","affiliation":[{"name":"Free Radical Biochemistry Laboratory, School of Biological Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carl","family":"Petersen","sequence":"additional","affiliation":[{"name":"School of Health Sciences, University of Canterbury, Private Bag 4800, Christchurch, New Zealand."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John G.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Steroid and Immunobiochemistry Laboratory, Canterbury Health Laboratories, P.O. 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