{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,28]],"date-time":"2026-02-28T00:50:42Z","timestamp":1772239842192,"version":"3.50.1"},"reference-count":42,"publisher":"Canadian Science Publishing","issue":"10","license":[{"start":{"date-parts":[[2017,10,1]],"date-time":"2017-10-01T00:00:00Z","timestamp":1506816000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":["cdnsciencepub.com"],"crossmark-restriction":false},"short-container-title":["Appl. Physiol. Nutr. Metab."],"published-print":{"date-parts":[[2017,10]]},"abstract":"<jats:p> Both the repeated-bout effect and increased flexibility have been linked to reduced muscle damage, fatigue, and strength loss after intense eccentric exercise. Our purpose was to compare the eccentric-training (ECC) response after first priming the muscles with either static flexibility training or a single intense bout of eccentric exercise. Twenty-five participants were randomly assigned to flexibility training (n = 8; 3\u00d7\/week; 30 min\/day), a single bout of intense eccentric exercise (n = 9), or no intervention (control; n = 8) during a 4-week priming phase, prior to completing a subsequent 4-week period of eccentric training of the knee flexors. Testing was completed prior to the priming phase, before ECC, during acute ECC (0 h, 24 h, and 48 h after bouts 1 and 4), and after ECC. Measures included muscle thickness (MT; via ultrasound); isometric, concentric, and eccentric strength; muscle power (dynamometer); electromyography; range of motion; optimal angle of peak torque; and soreness (visual analog scale). Flexibility training and single-bout groups had 47% less soreness at 48 h after the first bout of ECC compared with control (p &lt; 0.05). The flexibility training group had 10% less soreness at 48 h after the fourth ECC bout compared with both the single-bout and control groups (p &lt; 0.05). Isometric strength loss was attenuated for the flexibility training group (\u22129%) after the fourth ECC bout compared with control (\u221219%; p &lt; 0.05). All groups had similar increases in strength, MT, and power after ECC (p &lt; 0.05). Prior flexibility training may be more effective than a single session of eccentric exercise in reducing adverse symptoms during the acute stages of eccentric training; however, these benefits did not translate into greater performance after training. <\/jats:p>","DOI":"10.1139\/apnm-2017-0093","type":"journal-article","created":{"date-parts":[[2017,6,13]],"date-time":"2017-06-13T21:33:18Z","timestamp":1497389598000},"page":"1044-1053","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":7,"title":["Flexibility training and the repeated-bout effect: priming interventions prior to eccentric training of the knee flexors"],"prefix":"10.1139","volume":"42","author":[{"given":"Andrew W.","family":"Leslie","sequence":"first","affiliation":[{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."},{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joel L.","family":"Lanovaz","sequence":"additional","affiliation":[{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."},{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Justin W.","family":"Andrushko","sequence":"additional","affiliation":[{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."},{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jonathan P.","family":"Farthing","sequence":"additional","affiliation":[{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."},{"name":"College of Kinesiology, 87 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5B2, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","reference":[{"issue":"6","key":"refg1\/ref1","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1152\/jappl.2000.89.6.2249","volume":"89","author":"Aagaard P.","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"refg2\/ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ptsp.2011.02.005"},{"issue":"5","key":"refg3\/ref3","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1097\/00005768-200105000-00017","volume":"33","author":"Brockett C.L.","year":"2001","journal-title":"Med. Sci. Sports Exerc."},{"key":"refg4\/ref4","doi-asserted-by":"publisher","DOI":"10.2478\/hukin-2014-0027"},{"key":"refg5\/ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-865920"},{"key":"refg6\/ref6","doi-asserted-by":"publisher","DOI":"10.1249\/MSS.0b013e3181f315ad"},{"key":"refg7\/ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-9406(05)60630-X"},{"key":"refg8\/ref8","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1989.11.2.70"},{"key":"refg9\/ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinph.2009.10.040"},{"key":"refg10\/ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-003-0841-3"},{"key":"refg11\/ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-003-0842-2"},{"key":"refg12\/ref12","doi-asserted-by":"publisher","DOI":"10.1097\/JSM.0b013e3180f60b26"},{"issue":"3","key":"refg13\/ref13","doi-asserted-by":"crossref","first-page":"1179","DOI":"10.1152\/jappl.2000.89.3.1179","volume":"89","author":"Fowles J.R.","year":"2000","journal-title":"J. Appl. Physiol."},{"key":"refg14\/ref14","doi-asserted-by":"publisher","DOI":"10.2165\/00007256-200636020-00004"},{"key":"refg15\/ref15","doi-asserted-by":"publisher","DOI":"10.1002\/mus.880170604"},{"key":"refg17\/ref17","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-199701000-00015"},{"key":"refg18\/ref18","unstructured":"Inman, V.T., Ralston, H.J., and Todd, F. 1981. Human walking. William and Wilkins, Baltimore, Md., USA. pp. 89\u2013100."},{"key":"refg19\/ref19","doi-asserted-by":"publisher","DOI":"10.1249\/mss.0b013e3181238a2b"},{"key":"refg20\/ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-010-1513-8"},{"issue":"6","key":"refg21\/ref21","first-page":"397","volume":"23","author":"Kujala U.M.","year":"1997","journal-title":"Current trends in treatment and prevention. Sports Med."},{"key":"refg22\/ref22","doi-asserted-by":"publisher","DOI":"10.1123\/jsr.6.1.38"},{"key":"refg23\/ref23","doi-asserted-by":"publisher","DOI":"10.1177\/03635465990270050801"},{"key":"refg24\/ref24","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2017.00120"},{"key":"refg25\/ref25","doi-asserted-by":"publisher","DOI":"10.1142\/S0219519402000423"},{"issue":"3","key":"refg26\/ref26","first-page":"254","volume":"39","author":"Nelson R.T.","year":"2004","journal-title":"J. Athl. Train."},{"key":"refg27\/ref27","doi-asserted-by":"publisher","DOI":"10.1097\/00005768-200109000-00011"},{"key":"refg28\/ref28","doi-asserted-by":"publisher","DOI":"10.1002\/1097-4598(200011)23:11<1727::AID-MUS9>3.3.CO;2-P"},{"key":"refg29\/ref29","first-page":"64","volume":"11","author":"Peake J.","year":"2005","journal-title":"Exerc. Immunol. Rev."},{"issue":"3","key":"refg30\/ref30","first-page":"439","volume":"12","author":"Perchthaler D.","year":"2013","journal-title":"J. Sports Sci. Med."},{"key":"refg31\/ref31","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511419277"},{"key":"refg32\/ref32","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000089246.90005.47"},{"key":"refg33\/ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-008-0980-7"},{"key":"refg34\/ref34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1681.2004.04028.x"},{"key":"refg43\/ref43","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.2008.051417"},{"issue":"3","key":"refg35\/ref35","doi-asserted-by":"crossref","first-page":"867","DOI":"10.1152\/jappl.1997.83.3.867","volume":"83","author":"Ryschon T.W.","year":"1997","journal-title":"J. Appl. Physiol."},{"key":"refg36\/ref36","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-817892"},{"issue":"5","key":"refg37\/ref37","doi-asserted-by":"crossref","first-page":"298","DOI":"10.5694\/j.1326-5377.1993.tb137863.x","volume":"159","author":"Seward H.","year":"1993","journal-title":"Med. J. Aust."},{"key":"refg38\/ref38","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1994.19.1.12"},{"key":"refg39\/ref39","doi-asserted-by":"publisher","DOI":"10.1080\/02701367.1993.10608784"},{"key":"refg40\/ref40","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1989.10.9.343"},{"key":"refg41\/ref41","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.1991.14.1.31"},{"key":"refg42\/ref42","doi-asserted-by":"publisher","DOI":"10.2519\/jospt.2001.31.12.730"}],"container-title":["Applied Physiology, Nutrition, and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/cdnsciencepub.com\/doi\/full-xml\/10.1139\/apnm-2017-0093","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/cdnsciencepub.com\/doi\/pdf\/10.1139\/apnm-2017-0093","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T15:32:08Z","timestamp":1751470328000},"score":1,"resource":{"primary":{"URL":"https:\/\/cdnsciencepub.com\/doi\/10.1139\/apnm-2017-0093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,10]]},"references-count":42,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2017,10]]}},"alternative-id":["10.1139\/apnm-2017-0093"],"URL":"https:\/\/doi.org\/10.1139\/apnm-2017-0093","relation":{},"ISSN":["1715-5312","1715-5320"],"issn-type":[{"value":"1715-5312","type":"print"},{"value":"1715-5320","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,10]]},"assertion":[{"value":"2017-02-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-06","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}