{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T03:46:22Z","timestamp":1792122382193,"version":"4.4.0"},"reference-count":48,"publisher":"Canadian Science Publishing","issue":"9","license":[{"start":{"date-parts":[[2018,9,1]],"date-time":"2018-09-01T00:00:00Z","timestamp":1535760000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":["cdnsciencepub.com"],"crossmark-restriction":false},"short-container-title":["Appl. Physiol. Nutr. Metab."],"published-print":{"date-parts":[[2018,9]]},"abstract":"<jats:p> The purpose of this study was to investigate the effects of l-arginine supplementation on muscle recovery after a single session of high-intensity resistance exercise (RE). Twenty healthy young adult participants (22.8 \u00b1 3.4 years old) were assigned to 1 of 2 groups (N = 10 per group): a placebo-supplement group or an l-arginine-supplement group. The groups completed a session of high-intensity RE (0 h) and 3 subsequent fatigue test sessions (at 24, 48, and 72 h postexercise) to assess the time course of muscle recovery. During the test sessions, we assessed the following dependent variables: number of maximum repetitions, electromyographic signal (i.e., root mean square (RMS) and median frequency (MF) slope), muscle soreness, perceived exertion, blood levels of creatine kinase (CK) and lactate, and testosterone:cortisol ratio. Number of maximum repetitions increased at 48 and 72 h postexercise in both groups (time, P &lt; 0.05). CK levels and muscle soreness increased at 24 h postexercise and then progressively returned to baseline at 72 h post exercise in both groups (time, P &lt; 0.05). Lactate levels increased immediately postexercise but were reduced at 24 h postexercise in both groups (time, P &lt; 0.05). Testosterone:cortisol ratio, RMS, and MF slope remained unchanged during the recovery period in both groups (time, P &gt; 0.05). No significant (P &gt; 0.05) group \u00d7 time interaction was found for all dependent variables during the recovery period. In conclusion, our data indicate that l-arginine supplementation does not improve muscle recovery following a high-intensity RE session in young adults. <\/jats:p>","DOI":"10.1139\/apnm-2017-0594","type":"journal-article","created":{"date-parts":[[2018,3,15]],"date-time":"2018-03-15T21:34:28Z","timestamp":1521149668000},"page":"928-936","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["<scp>l<\/scp>-Arginine supplementation does not improve muscle function during recovery from resistance exercise"],"prefix":"10.1139","volume":"43","author":[{"given":"Walquiria Batista","family":"Andrade","sequence":"first","affiliation":[{"name":"Center of Research in Health Sciences, North University of Paran\u00e1 (UNOPAR), Londrina, Paran\u00e1 86041-120, Brazil."},{"name":"Center of Research in Health Sciences, North University of Paran\u00e1 (UNOPAR), Londrina, Paran\u00e1 86041-120, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeferson Lucas","family":"Jacinto","sequence":"additional","affiliation":[{"name":"Center of Research in Health Sciences, North University of Paran\u00e1 (UNOPAR), Londrina, Paran\u00e1 86041-120, Brazil."},{"name":"Center of Research in Health Sciences, North University of Paran\u00e1 (UNOPAR), Londrina, Paran\u00e1 86041-120, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas Kratki","family":"da Silva","sequence":"additional","affiliation":[{"name":"Center of Research in Health Sciences, North University of Paran\u00e1 (UNOPAR), Londrina, Paran\u00e1 86041-120, Brazil."},{"name":"Center of Research in Health Sciences, North University of Paran\u00e1 (UNOPAR), Londrina, Paran\u00e1 86041-120, Brazil."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mirela Casonato","family":"Roveratti","sequence":"additional","affiliation":[{"name":"Center of Research in Health 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