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Metab."],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:p>The aim of this study was to investigate age-related differences in motor unit (MU) recruitment patterns and firing rates (MUFRs) during maximal volitional isometric contractions (MVC) of the knee extensors and during a fatiguing maximal contraction. Twenty men (22\u00a0\u00b1\u00a03\u00a0years) and 20 boys (10\u00a0\u00b1\u00a01\u00a0years) completed a ramped MVC and a 50\u2009s maximal contraction. Surface electromyography (sEMG) was recorded from the vastus lateralis and decomposed into individual MU action potential trains. MVC relative to lean body mass was greater ( p\u00a0&lt;\u00a00.001) in men (4.3\u00a0\u00b1\u00a00.9\u2009Nm\/kg) than in boys (2.6\u00a0\u00b1\u00a00.7\u2009Nm\/kg). During the ramped MVC, MUFR was higher ( p\u00a0&lt;\u00a00.001), and the MUFR\u2013recruitment threshold (RT) slope was steeper in men than in boys ( p\u00a0=\u00a00.005). During the fatiguing contraction, torque decreased more in men (52\u00a0\u00b1\u00a024%) than in boys (40\u00a0\u00b1\u00a022%), but the difference was not significant ( p\u00a0=\u00a00.13). Both groups experienced a significant decline in MUFRs over the course of the fatiguing contraction ( p\u00a0&lt;\u00a00.001). Furthermore, there was a significant age \u00d7 time interaction ( p\u00a0&lt;\u00a00.001), wherein MUFRs decreased linearly in boys but remained initially stable with a steep decrease in the last 20\u2009s in men. Our findings suggest that children have different neuromotor strategies to complete maximal and fatiguing tasks compared with adults, possibly related to children\u2019s lower maximal strength and greater fatigue resistance.<\/jats:p>","DOI":"10.1139\/apnm-2026-0010","type":"journal-article","created":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T21:33:51Z","timestamp":1787780031000},"page":"1-12","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["Age-related differences in maximal strength and muscle fatigue: association with motor unit activation patterns"],"prefix":"10.1139","volume":"51","author":[{"given":"McKenna","family":"Faragher","sequence":"first","affiliation":[{"name":"Brock University","place":["St. Catharines, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"McKiel","sequence":"additional","affiliation":[{"name":"Brock University","place":["St. Catharines, Canada"]},{"name":"Brock University","place":["St. Catharines, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Jevtic","sequence":"additional","affiliation":[{"name":"Brock University","place":["St. Catharines, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1918-1695","authenticated-orcid":false,"given":"Michael W.R.","family":"Holmes","sequence":"additional","affiliation":[{"name":"Brock University","place":["St. Catharines, Canada"]},{"name":"Brock University","place":["St. Catharines, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shawn M.","family":"Beaudette","sequence":"additional","affiliation":[{"name":"Brock University","place":["St. Catharines, Canada"]},{"name":"Brock University","place":["St. Catharines, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7105-0185","authenticated-orcid":false,"given":"Bareket","family":"Falk","sequence":"additional","affiliation":[{"name":"Brock University","place":["St. Catharines, Canada"]},{"name":"Brock University","place":["St. Catharines, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"refg1\/ref1","doi-asserted-by":"publisher","DOI":"10.1123\/pes.22.2.205"},{"key":"refg2\/ref2","doi-asserted-by":"publisher","DOI":"10.1152\/jappl.1955.7.6.593"},{"key":"refg3\/ref3","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1983.sp014765"},{"key":"refg4\/ref4","doi-asserted-by":"crossref","DOI":"10.3389\/fphys.2018.00387","volume":"9","author":"Birat A.","year":"2018","journal-title":"Front. 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