{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,16]],"date-time":"2026-07-16T04:11:09Z","timestamp":1784175069150,"version":"3.55.0"},"reference-count":45,"publisher":"Canadian Science Publishing","issue":"11","license":[{"start":{"date-parts":[[2013,11,1]],"date-time":"2013-11-01T00:00:00Z","timestamp":1383264000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Can. J. Microbiol."],"published-print":{"date-parts":[[2013,11]]},"abstract":"<jats:p> We investigated the prevalence of extended-spectrum \u03b2-lactamase (ESBL)-producing Escherichia coli in untreated hospital wastewaters and 2 sewage treatment plants (STPs). A collection of 252 ESBL-producing E. coli isolates from hospital wastewater and STPs were typed and tested for resistance to 17 antimicrobial agents and for the presence of integron-associated integrases (intI gene) and ESBL genes. Eighty-nine percent (n = 176) of the ESBL-producing E. coli strains from hospital wastewater were found in more than 1 sample (common types), with 1 common type accounting for 35% of isolates, found in all samples. These strains were also resistant to up to 9 non-\u03b2-lactam antibiotics and showed the same pattern of resistance in all samples. More than 73% of the hospital wastewater isolates possessed SHV-type ESBL as opposed to isolates from STPs that carried only CTX-M-type ESBL genes. The prevalence of the intI gene did not differ between the sources of the isolates. Certain ESBL-producing E. coli were dominant in hospital wastewaters. These strains possessed \u03b2-lactamase genes that were different from isolates found in STPs. From a public health point of view, the presence of such a high level of ESBL-producing E. coli strains in hospital wastewaters is of great importance. <\/jats:p>","DOI":"10.1139\/cjm-2013-0515","type":"journal-article","created":{"date-parts":[[2013,10,1]],"date-time":"2013-10-01T17:40:37Z","timestamp":1380649237000},"page":"737-745","source":"Crossref","is-referenced-by-count":31,"title":["Extended-spectrum \u03b2-lactamase producing <i>Escherichia coli<\/i> in hospital wastewaters and sewage treatment plants in Queensland, Australia"],"prefix":"10.1139","volume":"59","author":[{"given":"Aycan","family":"G\u00fcndo\u011fdu","sequence":"first","affiliation":[{"name":"GeneCology Research Centre, School of Health and Sport Sciences, Faculty of Science, Health and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy V.","family":"Jennison","sequence":"additional","affiliation":[{"name":"Public Health Microbiology, Communicable Disease, Queensland Health Forensic and Scientific Services, Coopers Plains, Queensland, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen V.","family":"Smith","sequence":"additional","affiliation":[{"name":"Public Health Microbiology, Communicable Disease, Queensland Health Forensic and Scientific Services, Coopers Plains, Queensland, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helen","family":"Stratton","sequence":"additional","affiliation":[{"name":"School of Biomolecular and Physical Sciences, Griffith University, Nathan Campus, Southport, Queensland, Australia."},{"name":"Smart Water Research Centre, Southport, Queensland, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Katouli","sequence":"additional","affiliation":[{"name":"GeneCology Research Centre, School of Health and Sport Sciences, Faculty of Science, Health and Education, University of the Sunshine Coast, Maroochydore DC 4558, Queensland, Australia."},{"name":"Smart Water Research Centre, Southport, Queensland, Australia."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"refg4\/ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2008.05.006"},{"key":"refg5\/ref5","unstructured":"Bell, S.M., Gatus, B.J., Pham, J.N., and Rafferty, D.L. 2006. 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