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They cause infections in vertebrates and invertebrates and are considered to be an emerging pathogen in humans, producing intestinal and extra-intestinal diseases. Most of the clinical isolates correspond to A. hydrophila, A. caviae, and A. veronii bv. Sobria, which are described as the causative agents of wound infections, septicaemia, and meningitis in immunocompromised people, and diarrhoea and dysenteric infections in the elderly and children. The pathogenic factors associated with Aeromonas are multifactorial and involve structural components, siderophores, quorum-sensing mechanisms, secretion systems, extracellular enzymes, and exotoxins. In this study, we analysed a representative number of clinical and environmental strains belonging to the A. hydrophila species complex to evaluate their potential pathogenicity. We thereby detected their enzymatic activities and antibiotic susceptibility pattern and the presence of virulence genes (aer, alt, ast, and ascV). The notably high prevalence of these virulence factors, even in environmental strains, indicated a potential pathogenic capacity. Additionally, we determined the adhesion capacity and cytopathic effects of this group of strains in Caco-2 cells. Most of the strains exhibited adherence and caused complete lysis. <\/jats:p>","DOI":"10.1139\/cjm-2015-0466","type":"journal-article","created":{"date-parts":[[2015,12,17]],"date-time":"2015-12-17T22:40:17Z","timestamp":1450392017000},"page":"296-306","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":22,"title":["Potential pathogenicity of <i>Aeromonas hydrophila<\/i> complex strains isolated from clinical, food, and environmental sources"],"prefix":"10.1139","volume":"62","author":[{"given":"Vicenta","family":"Albarral","sequence":"first","affiliation":[{"name":"Departament de Microbiologia i Parasitologia Sanit\u00e0ries, Facultat de Farm\u00e0cia, Universitat de Barcelona, Avinguda Joan XXIII s\/n, Barcelona 08028, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadna","family":"Sanglas","sequence":"additional","affiliation":[{"name":"Departament de Microbiologia i Parasitologia Sanit\u00e0ries, Facultat de Farm\u00e0cia, Universitat de Barcelona, Avinguda Joan XXIII s\/n, Barcelona 08028, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Montserrat","family":"Palau","sequence":"additional","affiliation":[{"name":"Departament de Microbiologia i Parasitologia Sanit\u00e0ries, Facultat de Farm\u00e0cia, Universitat de Barcelona, Avinguda Joan XXIII s\/n, Barcelona 08028, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mi\u00f1ana-Galbis","sequence":"additional","affiliation":[{"name":"Departament de Microbiologia i Parasitologia Sanit\u00e0ries, Facultat de Farm\u00e0cia, Universitat de Barcelona, Avinguda Joan XXIII s\/n, Barcelona 08028, Spain."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. 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