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Notably, the aggregates of PABPs formed upon infection are mainly found in the nucleus, which is a different response from that found after exposure to heat shock. Pyrimethamine treatment of the infected monolayers inhibits the multiplicity of the parasite and reverses the relocalization of PABP aggregates. This active interaction between the infected mammalian host cells and T. gondii appears to be different from that caused by viral infection. <\/jats:p>","DOI":"10.1139\/cjm-2017-0755","type":"journal-article","created":{"date-parts":[[2018,4,15]],"date-time":"2018-04-15T18:49:33Z","timestamp":1523818173000},"page":"551-558","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":2,"title":["<i>Toxoplasma gondii<\/i> infection induces the formation of host\u2019s nuclear granules containing poly(A)-binding proteins"],"prefix":"10.1139","volume":"64","author":[{"given":"Karlee","family":"Fischer","sequence":"first","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."},{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikayla","family":"Roberts","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."},{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Roscoe","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."},{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yasin","family":"Avci","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."},{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sirinart","family":"Ananvoranich","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."},{"name":"Department of Chemistry and Biochemistry, University of Windsor, Windsor, ON N9B 3P4, Canada."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","reference":[{"key":"refg1\/ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2007.12.003"},{"key":"refg2\/ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s40268-017-0206-8"},{"key":"refg3\/ref3","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.64.3.607-623.2000"},{"key":"refg4\/ref4","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-micro-091014-104100"},{"key":"refg5\/ref5","doi-asserted-by":"publisher","DOI":"10.1111\/cmi.12255"},{"key":"refg6\/ref6","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20111474"},{"key":"refg7\/ref7","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.087692"},{"key":"refg8\/ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2013.04.006"},{"key":"refg9\/ref9","doi-asserted-by":"publisher","unstructured":"Dao, D., Fraser, A.N., Hung, J., Ljosa, V., Singh, S., and Carpenter, A.E. 2016. 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