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Normal physiologic adaptations to pregnancy, including increased cardiac output and plasma volume, may unmask cardiac conditions, exacerbate previously existing conditions, or create de novo complications. It is important for care providers to understand the normal physiologic changes of pregnancy and how they may impact the care of patients with cardiovascular disease. This review outlines the physiologic adaptions during pregnancy and their pathologic implications for some of the more common cardiovascular conditions in pregnancy. <\/jats:p>","DOI":"10.1139\/cjpp-2024-0010","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T22:38:22Z","timestamp":1717108702000},"page":"552-571","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":21,"title":["Cardiac physiology and pathophysiology in pregnancy"],"prefix":"10.1139","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0009-0004-1412-9064","authenticated-orcid":false,"given":"Shekoofeh Saboktakin","family":"Rizi","sequence":"first","affiliation":[{"name":"University of Manitoba","place":["Winnipeg, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8173-9362","authenticated-orcid":false,"given":"Evan","family":"Wiens","sequence":"additional","affiliation":[{"name":"University of Alberta","place":["Edmonton, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Hunt","sequence":"additional","affiliation":[{"name":"University of Manitoba","place":["Winnipeg, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robin","family":"Ducas","sequence":"additional","affiliation":[{"name":"University of Manitoba","place":["Winnipeg, Canada"]},{"name":"University of Manitoba","place":["Winnipeg, Canada"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"refg1\/ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2014.01.007"},{"key":"refg2\/ref2","doi-asserted-by":"publisher","DOI":"10.4137\/CMC.S40191"},{"key":"refg3\/ref3","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy080"},{"key":"refg4\/ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0735-1097(00)01198-0"},{"key":"refg5\/ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s12884-019-2619-6"},{"key":"refg6\/ref6","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003243"},{"key":"refg7\/ref7","doi-asserted-by":"publisher","DOI":"10.1038\/hr.2014.128"},{"key":"refg8\/ref8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100377"},{"key":"refg10\/ref10","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000002501"},{"key":"refg11\/ref11","doi-asserted-by":"publisher","DOI":"10.1097\/aog.0000000000002355"},{"key":"refg12\/ref12","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003891"},{"key":"refg13\/ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.hlc.2019.09.011"},{"key":"refg14\/ref14","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2014-305597"},{"issue":"3","key":"refg15\/ref15","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1002\/uog.20137","volume":"54","author":"Balen V.A.L.","year":"2019","journal-title":"Ultrasound Obstet. 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