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J. Physiol. Pharmacol."],"published-print":{"date-parts":[[2026,1,1]]},"abstract":"<jats:p>\n                    Maintaining temporal coordination of physiological function is essential for good health. To determine how the endothelin axis regulates the timing of blood pressure (BP) and key physiological rhythms, we monitored circadian rhythmicity of BP and other variables by telemetry in male and female Sprague Dawley rats with or without chronic ET\n                    <jats:sub>B<\/jats:sub>\n                    receptor blockade (A-192621). Rats were maintained under constant dark conditions to ensure a free-running status of the circadian clock. Rats were divided into groups being fed either normal salt (NS) or high salt (HS) diets starting the day of release into constant darkness. After 1 week, a subset of rats was given A-192621 in the food for 2 weeks. HS diet exacerbated amplitude of mean arterial pressure (MAP) in ET\n                    <jats:sub>B<\/jats:sub>\n                    antagonist-treated rats. ET\n                    <jats:sub>B<\/jats:sub>\n                    antagonism was sufficient to delay MAP rhythms in either diet. There were no changes in amplitude of heart rate (HR) or body temperature resulting in desynchrony between the phases with MAP. Rats fed an HS diet without an antagonist also displayed desynchrony among all peripheral rhythms. Together, these data support the notion of the endothelial system regulating BP rhythms and maintaining synchrony with peripheral physiological rhythms.\n                  <\/jats:p>","DOI":"10.1139\/cjpp-2026-0189","type":"journal-article","created":{"date-parts":[[2026,9,26]],"date-time":"2026-09-26T21:33:51Z","timestamp":1790458431000},"page":"1-13","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":0,"title":["ET\n                    <sub>B<\/sub>\n                    receptors contribute to synchrony between blood pressure and other peripheral circadian rhythms in the Sprague Dawley rat"],"prefix":"10.1139","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1762-1554","authenticated-orcid":false,"given":"Maria","family":"Venegas","sequence":"first","affiliation":[{"name":"University of Alabama at Birmingham","place":["Birmingham, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hiruni 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