{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T12:53:07Z","timestamp":1787662387573,"version":"build-2736575974"},"reference-count":36,"publisher":"Canadian Science Publishing","issue":"6","license":[{"start":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T00:00:00Z","timestamp":1180656000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genome"],"published-print":{"date-parts":[[2007,6]]},"abstract":"<jats:p> Cadmium (Cd) is a nonessential heavy metal that is highly toxic to living cells at very low concentrations. Most of the Cd in plants derives from soils. Owing to the large amounts consumed, cereals are the major source of dietary Cd, and Cd content in oat can exceed accepted limits. Plants have a set of mechanisms that control the uptake, accumulation, trafficking, and detoxification of Cd and other metals. Genetic factors affect the variation in Cd level between plant species and cultivars, and the development of cultivars that poorly accumulate Cd is a worthwhile goal. Because of the expense of Cd screening, the use of molecular markers linked to low Cd accumulation could be an alternative to phenotyping for selection. In this study, such markers were sought using bulked-segregant analysis in an F<jats:sub>2<\/jats:sub> population from the cross between oat cultivars \u2018Aslak\u2019 and \u2018Salo\u2019, the second of which is known to be a high Cd accumulator. Four markers associated with grain Cd concentration were found: 2 RAPDs (random amplified polymorphic DNAs), 1 REMAP (retrotransposon-microsatellite amplified polymorphism), and 1 SRAP (sequence-related amplified polymorphism). The first 3 were converted into more reproducible SCAR (sequence-characterized amplified region) markers. The 4 markers were assigned to 1 linkage group that exhibited a QTL (quantitative trait locus) representing a major gene for grain Cd concentration. <\/jats:p>","DOI":"10.1139\/g07-036","type":"journal-article","created":{"date-parts":[[2007,7,13]],"date-time":"2007-07-13T14:48:08Z","timestamp":1184338088000},"page":"588-594","source":"Crossref","is-referenced-by-count":52,"title":["A major gene for grain cadmium accumulation in oat (<i>Avena sativa<\/i> L.)"],"prefix":"10.1139","volume":"50","author":[{"given":"Pirjo","family":"Tanhuanp\u00e4\u00e4","sequence":"first","affiliation":[{"name":"Plant Genomics, Biotechnology and Food Research, MTT Agrifood Research Finland, FI-31600 Jokioinen, Finland."},{"name":"MTT\/BI Plant Genomics Laboratory, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, P.O. Box 56, Viikinkaari 4, FI-00014 Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruslan","family":"Kalendar","sequence":"additional","affiliation":[{"name":"Plant Genomics, Biotechnology and Food Research, MTT Agrifood Research Finland, FI-31600 Jokioinen, Finland."},{"name":"MTT\/BI Plant Genomics Laboratory, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, P.O. Box 56, Viikinkaari 4, FI-00014 Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan H.","family":"Schulman","sequence":"additional","affiliation":[{"name":"Plant Genomics, Biotechnology and Food Research, MTT Agrifood Research Finland, FI-31600 Jokioinen, Finland."},{"name":"MTT\/BI Plant Genomics Laboratory, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, P.O. Box 56, Viikinkaari 4, FI-00014 Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elina","family":"Kiviharju","sequence":"additional","affiliation":[{"name":"Plant Genomics, Biotechnology and Food Research, MTT Agrifood Research Finland, FI-31600 Jokioinen, Finland."},{"name":"MTT\/BI Plant Genomics Laboratory, Institute of Biotechnology, Viikki Biocenter, University of Helsinki, P.O. Box 56, Viikinkaari 4, FI-00014 Helsinki, Finland."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"atypb1\/ref1","doi-asserted-by":"crossref","unstructured":"Adriano, D.C. 2001. Trace elements in terrestrial environments. Springer, New York.","DOI":"10.1007\/978-0-387-21510-5"},{"key":"atypb2\/ref2","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/25.17.3389"},{"key":"atypb3\/ref3","doi-asserted-by":"crossref","first-page":"1722","DOI":"10.2135\/cropsci1997.0011183X003700060008x","volume":"37","author":"Clarke J.M.","year":"1997","journal-title":"Crop Sci."},{"key":"atypb4\/ref4","doi-asserted-by":"crossref","first-page":"27","DOI":"10.4141\/P01-083","volume":"82","author":"Clarke J.M.","year":"2002","journal-title":"Can. J. Plant Sci."},{"key":"atypb5\/ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s004250000458"},{"key":"atypb6\/ref6","doi-asserted-by":"publisher","DOI":"10.1104\/pp.123.3.825"},{"key":"atypb7\/ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0048-9697(01)01099-3"},{"key":"atypb8\/ref8","doi-asserted-by":"publisher","DOI":"10.1021\/jf020893+"},{"key":"atypb9\/ref999","first-page":"1","volume":"77","author":"European Commission","year":"2001","journal-title":"Off. J. Eur. Communities Legis."},{"key":"atypb10\/ref9","first-page":"44207","volume":"68","author":"Food and Drug Administration","year":"2003","journal-title":"Fed. Regist."},{"key":"atypb11\/ref10","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1469-1809.1947.tb02374.x","volume":"14","author":"Haldane J.B.S.","year":"1947","journal-title":"Ann. Eugen."},{"key":"atypb12\/ref11","doi-asserted-by":"crossref","first-page":"19789","DOI":"10.1074\/jbc.271.33.19789","volume":"271","author":"He Z.H.","year":"1996","journal-title":"J. Biol. Chem."},{"key":"atypb13\/ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtemb.2005.02.010"},{"key":"atypb14\/ref13","doi-asserted-by":"publisher","DOI":"10.1104\/pp.105.066910"},{"key":"atypb15\/ref14","doi-asserted-by":"publisher","DOI":"10.1007\/BF00016965"},{"key":"atypb16\/ref15","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2006.377"},{"key":"atypb17\/ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s001220051124"},{"key":"atypb18\/ref17","first-page":"18","volume":"115","author":"Karlsson T.","year":"1994","journal-title":"Lantmannen"},{"key":"atypb19\/ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0749-3797(00)00287-7"},{"key":"atypb20\/ref19","doi-asserted-by":"publisher","DOI":"10.1023\/B:BIOM.0000045727.76054.f3"},{"key":"atypb21\/ref20","doi-asserted-by":"crossref","first-page":"684","DOI":"10.1007\/BF00473530","volume":"326","author":"Kumpulainen J.","year":"1987","journal-title":"Fresenius J. Anal. Chem."},{"key":"atypb22\/ref21","doi-asserted-by":"publisher","DOI":"10.1016\/0888-7543(87)90010-3"},{"key":"atypb23\/ref22","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0065-2113(08)60542-8","volume":"55","author":"Lee M.","year":"1995","journal-title":"Adv. Agron."},{"key":"atypb24\/ref23","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.1976.tb23122.x"},{"key":"atypb25\/ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s001220100570"},{"key":"atypb26\/ref25","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1111\/j.1469-1809.1936.tb02144.x","volume":"7","author":"Mather K.","year":"1936","journal-title":"Ann. Eugen."},{"key":"atypb27\/ref26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.88.21.9828"},{"key":"atypb28\/ref27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8137.2006.01756.x"},{"key":"atypb29\/ref28","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1139\/g95-070","volume":"38","author":"Penner G.A.","year":"1995","journal-title":"Genome"},{"key":"atypb30\/ref29","unstructured":"Rozen, S., and Skaletsky, H.J. 2000. Primer3 on the WWW for general users and for biologist programmers. In Bioinformatics methods and protocols: Methods in molecular biology. Edited by S. Krawetz and S. Misener. Humana Press, Totowa, N.J. pp.\u00a0365\u2013386."},{"key":"atypb31\/ref30","first-page":"255","volume":"25","author":"Sippola J.","year":"1986","journal-title":"Ann. Agric. Fenn."},{"key":"atypb32\/ref31","doi-asserted-by":"publisher","DOI":"10.1104\/pp.103.022129"},{"key":"atypb33\/ref32","doi-asserted-by":"publisher","DOI":"10.1139\/G05-100"},{"key":"atypb34\/ref33","unstructured":"Tiessen, H. 1995. Introduction and synthesis. In Phosphorus in the global environment. Edited by H. Tiessen. Scientific Committee on Problems of the Environment (SCOPE). John Wiley & Sons, Ltd. pp.\u00a01\u20136."},{"key":"atypb35\/ref34","unstructured":"Van Ooijen, J.W., and Voorrips, R.E. 2001. JoinMap\u00ae 3.0. Software for the calculation of genetic linkage maps. Plant Research International, Wageningen, the Netherlands."},{"key":"atypb36\/ref35","doi-asserted-by":"publisher","DOI":"10.1104\/pp.105.069005"}],"container-title":["Genome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/full-xml\/10.1139\/G07-036","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/G07-036","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,6]],"date-time":"2020-01-06T03:18:31Z","timestamp":1578280711000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/G07-036"}},"subtitle":[],"editor":[{"given":"J.","family":"Bell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"editor"}]}],"short-title":[],"issued":{"date-parts":[[2007,6]]},"references-count":36,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2007,6]]}},"alternative-id":["10.1139\/G07-036"],"URL":"https:\/\/doi.org\/10.1139\/g07-036","relation":{},"ISSN":["0831-2796","1480-3321"],"issn-type":[{"value":"0831-2796","type":"print"},{"value":"1480-3321","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,6]]}}}