{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T14:56:44Z","timestamp":1720537004238},"reference-count":0,"publisher":"Canadian Science Publishing","issue":"5","license":[{"start":{"date-parts":[[1990,10,1]],"date-time":"1990-10-01T00:00:00Z","timestamp":654739200000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Genome"],"published-print":{"date-parts":[[1990,10,1]]},"abstract":"<jats:p> The chromosome makeup of a 3-year-old crossbred heifer was examined in an attempt to explore the cytogenetic causes of her infertility. The heifer proved to be a mosaic carrying predominantly XY cells and with approximately 30% of cells lacking a normal Y. The minor population included cells carrying a dicentric isochromosome Y and a small proportion of XO cells. Histological features of the gonads and reproductive system suggest that the presence of cells resulting from isochromosome formation and the consequent loss of the Y chromosome segment required for testicular induction may have been causally related to the embryonic state of the gonads and malformation of the duct system noted in this heifer.Key words: isochromosome, infertility, isodicentric Y, gonadal dysgenesis, chromosome mosaicism. <\/jats:p>","DOI":"10.1139\/g90-104","type":"journal-article","created":{"date-parts":[[2011,4,24]],"date-time":"2011-04-24T12:26:14Z","timestamp":1303647974000},"page":"690-695","source":"Crossref","is-referenced-by-count":2,"title":["Isochromosome Y in an infertile heifer"],"prefix":"10.1139","volume":"33","author":[{"given":"L. E. L.","family":"Pinheiro","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. B.","family":"Mikich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. H.","family":"Bechara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I. L.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. K.","family":"Basrur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"155","container-title":["Genome"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/pdf\/10.1139\/g90-104","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,1,5]],"date-time":"2020-01-05T19:38:57Z","timestamp":1578253137000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.nrcresearchpress.com\/doi\/10.1139\/g90-104"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1990,10,1]]},"references-count":0,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1990,10,1]]}},"alternative-id":["10.1139\/g90-104"],"URL":"https:\/\/doi.org\/10.1139\/g90-104","relation":{},"ISSN":["0831-2796","1480-3321"],"issn-type":[{"value":"0831-2796","type":"print"},{"value":"1480-3321","type":"electronic"}],"subject":[],"published":{"date-parts":[[1990,10,1]]}}}