{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:46:27Z","timestamp":1780465587851,"version":"3.54.1"},"reference-count":35,"publisher":"Canadian Science Publishing","issue":"8","license":[{"start":{"date-parts":[[2020,8,1]],"date-time":"2020-08-01T00:00:00Z","timestamp":1596240000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/www.nrcresearchpress.com\/page\/about\/CorporateTextAndDataMining"}],"content-domain":{"domain":["cdnsciencepub.com"],"crossmark-restriction":false},"short-container-title":["Genome"],"published-print":{"date-parts":[[2020,8]]},"abstract":"<jats:p> Brucella spp., facultative intracellular pathogens that can persistently colonize animal host cells and cause zoonosis, affect public health and safety. A Brucella strain was isolated from yak in Qinghai Province. To detect whether this isolate could cause an outbreak of brucellosis and to reveal its genetic characteristics, several typing and whole-genome sequencing methods were applied to identify its species and genetic characteristics. Phylogenetic analysis based on MLVA and whole-genome sequencing revealed the genetic characteristics of the isolated strain. The results showed that the isolated strain is a B. suis biovar 1 smooth strain, and this isolate was named B. suis QH05. The results of comparative genomics and MLVA showed that B. suis QH05 is not a vaccine strain. Comparison with other B. suis strains isolated from humans and animals indicated that B. suis QH05 may be linked to specific animal and human sources. In conclusion, B. suis QH05 does not belong to the Brucella epidemic species in China, and as the first isolation of B. suis from yak, this strain expands the host range of B. suis. <\/jats:p>","DOI":"10.1139\/gen-2019-0101","type":"journal-article","created":{"date-parts":[[2020,5,8]],"date-time":"2020-05-08T21:35:32Z","timestamp":1588973732000},"page":"397-405","update-policy":"https:\/\/doi.org\/10.1139\/csp-crossmark-policy","source":"Crossref","is-referenced-by-count":6,"title":["First isolation and characterization of <i>Brucella suis<\/i> from yak"],"prefix":"10.1139","volume":"63","author":[{"given":"Xiaowen","family":"Yang","sequence":"first","affiliation":[{"name":"State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China."},{"name":"Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ning","family":"Wang","sequence":"additional","affiliation":[{"name":"Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofang","family":"Cao","sequence":"additional","affiliation":[{"name":"Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Bie","sequence":"additional","affiliation":[{"name":"Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhifeng","family":"Xing","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Center for Disease Control and Prevention, Haerbin 150030, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shihui","family":"Yin","sequence":"additional","affiliation":[{"name":"Heilongjiang Provincial Center for Disease Control and Prevention, Haerbin 150030, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hai","family":"Jiang","sequence":"additional","affiliation":[{"name":"State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingmin","family":"Wu","sequence":"additional","affiliation":[{"name":"Key Laboratory of Animal Epidemiology and Zoonosis of the Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"155","reference":[{"key":"refg1\/ref1","first-page":"1","volume":"55","author":"Alton G.G.","year":"1975","journal-title":"Monogr. 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